Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q2RAS0 (ACA5_ORYSJ)

Last modified February 9, 2010. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Probable calcium-transporting ATPase 5, plasma membrane-type
    EC=3.6.3.8
Alternative name(s):
    Ca(2+)-ATPase isoform 5
Gene names
Ordered Locus Names: Os11g0140400, LOC_Os11g04460
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Hide | Top

Protein attributes

Sequence length1017 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles By similarity.

Catalytic activity

ATP + H2O + Ca2+(Cis) = ADP + phosphate + Ca2+(Trans).

Enzyme regulation

Activated by calmodulin By similarity.

Subcellular location

Membrane; Multi-pass membrane protein By similarity.

Domain

The N-terminus contains an autoinhibitory calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion By similarity.

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. Type IIB subfamily.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10171017Probable calcium-transporting ATPase 5, plasma membrane-type
PRO_0000247304

Regions

Topological domain1 – 153153Cytoplasmic Potential
Transmembrane154 – 17421 Potential
Transmembrane177 – 19721 Potential
Topological domain198 – 22831Cytoplasmic Potential
Transmembrane229 – 24921 Potential
Transmembrane331 – 35121 Potential
Topological domain352 – 38433Cytoplasmic Potential
Transmembrane385 – 40521 Potential
Transmembrane803 – 82321 Potential
Topological domain824 – 8252Cytoplasmic Potential
Transmembrane826 – 84621 Potential
Transmembrane875 – 89521 Potential
Topological domain896 – 93843Cytoplasmic Potential
Transmembrane939 – 95921 Potential
Transmembrane973 – 99321 Potential
Topological domain994 – 101724Cytoplasmic Potential

Sites

Active site43414-aspartylphosphate intermediate By similarity
Metal binding7361Magnesium By similarity
Metal binding7401Magnesium By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q2RAS0-1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 65910150C99609D8

FASTA1,017111,286
        10         20         30         40         50         60 
MEKLDRYLQE HFDVPAKNPS EEAQRRWRQA VGTIVKNRRR RFRWVPDLDR RSLDKAKVRS 

        70         80         90        100        110        120 
TQEKIRVALY VQQAALIFSD DELALITSKH DSKALKMHGG VDGISKKVRS SFDHGICASD 

       130        140        150        160        170        180 
LDTRQNIYGV NRYAEKPSRS FWMFVWDAFQ DMTLIILMVC ALLSVAVGLA TEGWPKGMYD 

       190        200        210        220        230        240 
GLGIILSIFL VVMVTAVSDY KQSLQFKELD NEKKKIFIHV TRDGRRQKIS IYDLVVGDIV 

       250        260        270        280        290        300 
HLSIGDQVPA DGLYIHGYSL LIDESSLSGE SDPVYVSQDK PFILAGTKVQ DGSAKMIVTA 

       310        320        330        340        350        360 
VGMRTEWGKL MSTLSEGGED ETPLQVKLNG VATVIGKIGL VFAILTFLVL LVRFLIDKGM 

       370        380        390        400        410        420 
TVGLLKWYST DALTIVNYFA TAVTIIVVAV PEGLPLAVTL SLAFAMKKLM NDKALVRHLS 

       430        440        450        460        470        480 
ACETMGSAGT ICTDKTGTLT TNYMVVDKIW ISEVSKSVTS NTISGELNSV VSSRTLSLLL 

       490        500        510        520        530        540 
QGIFENTSAE VVKEKDGKQT VLGTPTERAI LEFGLGLEGV HDAEYSACTK VKVEPFNSVK 

       550        560        570        580        590        600 
KKMAVLISLP SGTSRWFCKG ASEIILQMCD MMVDGDGNAI PLSEAQRKNI LDTINSFASD 

       610        620        630        640        650        660 
ALRTLCLAYK EVDDDIDDNA DSPTSGFTLI AIFGIKDPVR PGVKDAVKTC MSAGITVRMV 

       670        680        690        700        710        720 
TGDNINTAKA IAKECGILTE DGVAIEGPEF HSKSPEEMRD LIPNIQVMAR SLPLDKHTLV 

       730        740        750        760        770        780 
TNLRGMFDEV VSVTGDGTND APALHEADIG LAMGIAGTEV AKESADVIVL DDNFTTIINV 

       790        800        810        820        830        840 
ARWGRAVYIN IQKFVQFQLT VNIVALVINF VSACITGSAP LTAVQLLWVN MIMDTLGALA 

       850        860        870        880        890        900 
LATEPPNDEM MKRPPVRKGE SFITKVMWRN IMGQSLYQLF VLGALMFGGE SLLNIKGADS 

       910        920        930        940        950        960 
KSIINTLIFN SFVFCQVFNE INSREMQKIN VFRGIISNWI FIAVIAATVA FQVVIIEFLG 

       970        980        990       1000       1010 
TFASTVPLNW QHWLLSVGLG SISLIVGVIL KCIPVGSGET SATPNGYRPL ANGPDDI

« Hide

Hide | Top

References

[1]"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
The rice chromosomes 11 and 12 sequencing consortia
BMC Biol. 3:20-20(2005) [PubMed: 16188032] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.

Hide | Top

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DP000010 Genomic DNA. Translation: ABA91401.1.
RefSeqNP_001065710.1.
UniGeneOs.51580

3D structure databases

SMRQ2RAS0. Positions 100-994.
ModBaseSearch...

Genome annotation databases

GeneID4349735.
KEGGosa:4349735.

Organism-specific databases

GrameneQ2RAS0.

Phylogenomic databases

PhylomeDBQ2RAS0.

Family and domain databases

InterProIPR008250. ATPase_P-typ_ATPase-assoc-dom.
IPR006408. ATPase_P-typ_Ca-transp_PMCA.
IPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR000695. ATPase_P-typ_H-transp.
IPR001757. ATPase_P-typ_ion-transptr.
IPR018303. ATPase_P-typ_P_site.
IPR005834. Dehalogen-like_hydro.
[Graphical view]
PANTHERPTHR11939. ATPase_P. 1 hit.
PfamPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
PR00120. HATPASE.
SMARTSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01517. ATPase-IIB_Ca. 1 hit.
TIGR01494. ATPase_P-type. 4 hits.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameACA5_ORYSJ
AccessionPrimary (citable) accession number: Q2RAS0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: January 24, 2006
Last modified: February 9, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Hide | Top

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents