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Protein

Laccase-21

Gene

LAC21

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi89Copper 1By similarity1
Metal bindingi91Copper 2By similarity1
Metal bindingi134Copper 2By similarity1
Metal bindingi136Copper 3By similarity1
Metal bindingi484Copper 4By similarity1
Metal bindingi487Copper 1By similarity1
Metal bindingi489Copper 3By similarity1
Metal bindingi546Copper 3By similarity1
Metal bindingi547Copper 4By similarity1
Metal bindingi548Copper 2By similarity1
Metal bindingi552Copper 4By similarity1
Metal bindingi557Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLignin degradation
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-21 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 21
Diphenol oxidase 21
Urishiol oxidase 21
Gene namesi
Name:LAC21
Ordered Locus Names:Os11g0696900, LOC_Os11g47390
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000029190830 – 583Laccase-21Add BLAST554

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi85N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi282N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi311N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi384N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi387N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi399N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi409N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi446N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ2QZ80

Expressioni

Gene expression databases

ExpressionAtlasiQ2QZ80 differential
GenevisibleiQ2QZ80 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os11g47390.1

Structurei

3D structure databases

SMRiQ2QZ80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 155Plastocyanin-like 1Add BLAST117
Domaini165 – 323Plastocyanin-like 2Add BLAST159
Domaini436 – 567Plastocyanin-like 3Add BLAST132

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
HOGENOMiHOG000241916
InParanoidiQ2QZ80
KOiK05909
OMAiFLSCDRP
OrthoDBiEOG093606A1

Family and domain databases

CDDicd13849 CuRO_1_LCC_plant, 1 hit
cd13875 CuRO_2_LCC_plant, 1 hit
cd13897 CuRO_3_LCC_plant, 1 hit
Gene3Di2.60.40.4203 hits
InterProiView protein in InterPro
IPR001117 Cu-oxidase
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
IPR034288 CuRO_1_LCC
IPR034285 CuRO_2_LCC
IPR034289 CuRO_3_LCC
IPR017761 Laccase
PfamiView protein in Pfam
PF00394 Cu-oxidase, 1 hit
PF07731 Cu-oxidase_2, 1 hit
PF07732 Cu-oxidase_3, 1 hit
SUPFAMiSSF49503 SSF49503, 3 hits
TIGRFAMsiTIGR03389 laccase, 1 hit
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 1 hit
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QZ80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIAKIPAVL WLLACAVLTF AVAISPAHGG RTRRHYDFFI TETNYRRLCH
60 70 80 90 100
EKSVLTVNGQ FPGPTIYARK GDLVIVNVYN HGNKNITIHW HGVDQPRNPW
110 120 130 140 150
SDGPEFITQC PIRPDGKFTY QVIMSEEEGT LWWHAHSDFD RATVLGAIVV
160 170 180 190 200
HPKHGDTFPF KRPDKEIPII LGEWWKNDVN HLLEEMKRIG EDVKPSDANT
210 220 230 240 250
INGQPGDMFP CSRDDTFKVA VEHGNTYLLQ VINAGLTNDM FFAVSGHRLT
260 270 280 290 300
VVGIDARYTK PLTVEYIMIA PGQTMDLLLE ANRSLGSKSN SRYYMAARTF
310 320 330 340 350
ITLPVPIPFN NSTATAVVEY YTGDSGAGPP DFPAVLPSLD DVDAAMAFLR
360 370 380 390 400
QLRSLGSKDH PVHVPTHVDE HMLIDLAINF LPCNATNATD TACKGPKGNT
410 420 430 440 450
TRFAASLNNV SFVSPAIDVL HAYYYGSGRG VYEDDFPNNP APVFVNLTGD
460 470 480 490 500
NDRPGVTKHG AKVKVLEYGT VVEVVFQDTS FESHPMHLHG FAFYVVGLGS
510 520 530 540 550
GKFDDRRDPA TYNLLDPPYQ STVSVPKAGW AAIRFRADNP GVWFMHCHFD
560 570 580
RHMVWGMNTV FIVKDGKTPQ AQMLPRPPNM PKC
Length:583
Mass (Da):64,864
Last modified:January 24, 2006 - v1
Checksum:i14383B2F326D0A63
GO

Sequence cautioni

The sequence BAF28876 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000010 Genomic DNA Translation: ABA95555.1
AP008217 Genomic DNA Translation: BAF28876.2 Sequence problems.
AP014967 Genomic DNA Translation: BAT15353.1
AK241130 mRNA Translation: BAH00960.1
RefSeqiXP_015615527.1, XM_015760041.1
UniGeneiOs.72229

Genome annotation databases

EnsemblPlantsiOs11t0696900-01; Os11t0696900-01; Os11g0696900
GeneIDi4351179
GrameneiOs11t0696900-01; Os11t0696900-01; Os11g0696900
KEGGiosa:4351179

Similar proteinsi

Entry informationi

Entry nameiLAC21_ORYSJ
AccessioniPrimary (citable) accession number: Q2QZ80
Secondary accession number(s): A0A0P0Y5P2, B7F8L2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome