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Q2QZ80

- LAC21_ORYSJ

UniProt

Q2QZ80 - LAC21_ORYSJ

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Protein
Laccase-21
Gene
LAC21, Os11g0696900, LOC_Os11g47390
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi89 – 891Copper 1 By similarity
Metal bindingi91 – 911Copper 2 By similarity
Metal bindingi134 – 1341Copper 2 By similarity
Metal bindingi136 – 1361Copper 3 By similarity
Metal bindingi484 – 4841Copper 4 By similarity
Metal bindingi487 – 4871Copper 1 By similarity
Metal bindingi489 – 4891Copper 3 By similarity
Metal bindingi546 – 5461Copper 3 By similarity
Metal bindingi547 – 5471Copper 4 By similarity
Metal bindingi548 – 5481Copper 2 By similarity
Metal bindingi552 – 5521Copper 4 By similarity
Metal bindingi557 – 5571Copper 4 By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin biosynthetic process Source: EnsemblPlants/Gramene
  2. lignin catabolic process Source: UniProtKB-KW
  3. proanthocyanidin biosynthetic process Source: EnsemblPlants/Gramene
  4. response to copper ion Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-21 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 21
Diphenol oxidase 21
Urishiol oxidase 21
Gene namesi
Name:LAC21
Ordered Locus Names:Os11g0696900, LOC_Os11g47390
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 11

Organism-specific databases

GrameneiQ2QZ80.

Subcellular locationi

Secretedextracellular spaceapoplast Reviewed prediction

GO - Cellular componenti

  1. apoplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 Reviewed prediction
Add
BLAST
Chaini30 – 583554Laccase-21
PRO_0000291908Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi85 – 851N-linked (GlcNAc...) Reviewed prediction
Glycosylationi282 – 2821N-linked (GlcNAc...) Reviewed prediction
Glycosylationi311 – 3111N-linked (GlcNAc...) Reviewed prediction
Glycosylationi384 – 3841N-linked (GlcNAc...) Reviewed prediction
Glycosylationi387 – 3871N-linked (GlcNAc...) Reviewed prediction
Glycosylationi399 – 3991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi409 – 4091N-linked (GlcNAc...) Reviewed prediction
Glycosylationi446 – 4461N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os11g47390.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini39 – 155117Plastocyanin-like 1
Add
BLAST
Domaini165 – 323159Plastocyanin-like 2
Add
BLAST
Domaini436 – 567132Plastocyanin-like 3
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
OMAiVEYIMIA.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QZ80-1 [UniParc]FASTAAdd to Basket

« Hide

MGIAKIPAVL WLLACAVLTF AVAISPAHGG RTRRHYDFFI TETNYRRLCH    50
EKSVLTVNGQ FPGPTIYARK GDLVIVNVYN HGNKNITIHW HGVDQPRNPW 100
SDGPEFITQC PIRPDGKFTY QVIMSEEEGT LWWHAHSDFD RATVLGAIVV 150
HPKHGDTFPF KRPDKEIPII LGEWWKNDVN HLLEEMKRIG EDVKPSDANT 200
INGQPGDMFP CSRDDTFKVA VEHGNTYLLQ VINAGLTNDM FFAVSGHRLT 250
VVGIDARYTK PLTVEYIMIA PGQTMDLLLE ANRSLGSKSN SRYYMAARTF 300
ITLPVPIPFN NSTATAVVEY YTGDSGAGPP DFPAVLPSLD DVDAAMAFLR 350
QLRSLGSKDH PVHVPTHVDE HMLIDLAINF LPCNATNATD TACKGPKGNT 400
TRFAASLNNV SFVSPAIDVL HAYYYGSGRG VYEDDFPNNP APVFVNLTGD 450
NDRPGVTKHG AKVKVLEYGT VVEVVFQDTS FESHPMHLHG FAFYVVGLGS 500
GKFDDRRDPA TYNLLDPPYQ STVSVPKAGW AAIRFRADNP GVWFMHCHFD 550
RHMVWGMNTV FIVKDGKTPQ AQMLPRPPNM PKC 583
Length:583
Mass (Da):64,864
Last modified:January 24, 2006 - v1
Checksum:i14383B2F326D0A63
GO

Sequence cautioni

The sequence BAF28876.2 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DP000010 Genomic DNA. Translation: ABA95555.1.
AP008217 Genomic DNA. Translation: BAF28876.2. Sequence problems.
AK241130 mRNA. Translation: BAH00960.1.
RefSeqiNP_001068513.2. NM_001075045.2.
UniGeneiOs.34310.

Genome annotation databases

EnsemblPlantsiOS11T0696900-01; OS11T0696900-01; OS11G0696900.
GeneIDi4351179.
KEGGiosa:4351179.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DP000010 Genomic DNA. Translation: ABA95555.1 .
AP008217 Genomic DNA. Translation: BAF28876.2 . Sequence problems.
AK241130 mRNA. Translation: BAH00960.1 .
RefSeqi NP_001068513.2. NM_001075045.2.
UniGenei Os.34310.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os11g47390.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS11T0696900-01 ; OS11T0696900-01 ; OS11G0696900 .
GeneIDi 4351179.
KEGGi osa:4351179.

Organism-specific databases

Gramenei Q2QZ80.

Phylogenomic databases

eggNOGi COG2132.
HOGENOMi HOG000241916.
OMAi VEYIMIA.

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 3 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Oryza sativa full-length cDNA."
    The rice full-length cDNA consortium
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC21_ORYSJ
AccessioniPrimary (citable) accession number: Q2QZ80
Secondary accession number(s): B7F8L2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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