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Protein

Laccase-21

Gene

LAC21

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi89Copper 1By similarity1
Metal bindingi91Copper 2By similarity1
Metal bindingi134Copper 2By similarity1
Metal bindingi136Copper 3By similarity1
Metal bindingi484Copper 4By similarity1
Metal bindingi487Copper 1By similarity1
Metal bindingi489Copper 3By similarity1
Metal bindingi546Copper 3By similarity1
Metal bindingi547Copper 4By similarity1
Metal bindingi548Copper 2By similarity1
Metal bindingi552Copper 4By similarity1
Metal bindingi557Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-21 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 21
Diphenol oxidase 21
Urishiol oxidase 21
Gene namesi
Name:LAC21
Ordered Locus Names:Os11g0696900, LOC_Os11g47390
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 11

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_000029190830 – 583Laccase-21Add BLAST554

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi85N-linked (GlcNAc...)Sequence analysis1
Glycosylationi282N-linked (GlcNAc...)Sequence analysis1
Glycosylationi311N-linked (GlcNAc...)Sequence analysis1
Glycosylationi384N-linked (GlcNAc...)Sequence analysis1
Glycosylationi387N-linked (GlcNAc...)Sequence analysis1
Glycosylationi399N-linked (GlcNAc...)Sequence analysis1
Glycosylationi409N-linked (GlcNAc...)Sequence analysis1
Glycosylationi446N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ2QZ80.

Expressioni

Gene expression databases

GenevisibleiQ2QZ80. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os11g47390.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 155Plastocyanin-like 1Add BLAST117
Domaini165 – 323Plastocyanin-like 2Add BLAST159
Domaini436 – 567Plastocyanin-like 3Add BLAST132

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ2QZ80.
KOiK05909.
OMAiVEYIMIA.
OrthoDBiEOG093606A1.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QZ80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIAKIPAVL WLLACAVLTF AVAISPAHGG RTRRHYDFFI TETNYRRLCH
60 70 80 90 100
EKSVLTVNGQ FPGPTIYARK GDLVIVNVYN HGNKNITIHW HGVDQPRNPW
110 120 130 140 150
SDGPEFITQC PIRPDGKFTY QVIMSEEEGT LWWHAHSDFD RATVLGAIVV
160 170 180 190 200
HPKHGDTFPF KRPDKEIPII LGEWWKNDVN HLLEEMKRIG EDVKPSDANT
210 220 230 240 250
INGQPGDMFP CSRDDTFKVA VEHGNTYLLQ VINAGLTNDM FFAVSGHRLT
260 270 280 290 300
VVGIDARYTK PLTVEYIMIA PGQTMDLLLE ANRSLGSKSN SRYYMAARTF
310 320 330 340 350
ITLPVPIPFN NSTATAVVEY YTGDSGAGPP DFPAVLPSLD DVDAAMAFLR
360 370 380 390 400
QLRSLGSKDH PVHVPTHVDE HMLIDLAINF LPCNATNATD TACKGPKGNT
410 420 430 440 450
TRFAASLNNV SFVSPAIDVL HAYYYGSGRG VYEDDFPNNP APVFVNLTGD
460 470 480 490 500
NDRPGVTKHG AKVKVLEYGT VVEVVFQDTS FESHPMHLHG FAFYVVGLGS
510 520 530 540 550
GKFDDRRDPA TYNLLDPPYQ STVSVPKAGW AAIRFRADNP GVWFMHCHFD
560 570 580
RHMVWGMNTV FIVKDGKTPQ AQMLPRPPNM PKC
Length:583
Mass (Da):64,864
Last modified:January 24, 2006 - v1
Checksum:i14383B2F326D0A63
GO

Sequence cautioni

The sequence BAF28876 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000010 Genomic DNA. Translation: ABA95555.1.
AP008217 Genomic DNA. Translation: BAF28876.2. Sequence problems.
AP014967 Genomic DNA. Translation: BAT15353.1.
AK241130 mRNA. Translation: BAH00960.1.
RefSeqiXP_015615527.1. XM_015760041.1.
UniGeneiOs.72229.

Genome annotation databases

EnsemblPlantsiOS11T0696900-01; OS11T0696900-01; OS11G0696900.
GeneIDi4351179.
GrameneiOS11T0696900-01; OS11T0696900-01; OS11G0696900.
KEGGiosa:4351179.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000010 Genomic DNA. Translation: ABA95555.1.
AP008217 Genomic DNA. Translation: BAF28876.2. Sequence problems.
AP014967 Genomic DNA. Translation: BAT15353.1.
AK241130 mRNA. Translation: BAH00960.1.
RefSeqiXP_015615527.1. XM_015760041.1.
UniGeneiOs.72229.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os11g47390.1.

Proteomic databases

PaxDbiQ2QZ80.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS11T0696900-01; OS11T0696900-01; OS11G0696900.
GeneIDi4351179.
GrameneiOS11T0696900-01; OS11T0696900-01; OS11G0696900.
KEGGiosa:4351179.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ2QZ80.
KOiK05909.
OMAiVEYIMIA.
OrthoDBiEOG093606A1.

Gene expression databases

GenevisibleiQ2QZ80. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 3 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC21_ORYSJ
AccessioniPrimary (citable) accession number: Q2QZ80
Secondary accession number(s): A0A0P0Y5P2, B7F8L2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: November 30, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.