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Protein

Laccase-23

Gene

LAC23

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi80 – 801Copper 1By similarity
Metal bindingi82 – 821Copper 2By similarity
Metal bindingi125 – 1251Copper 2By similarity
Metal bindingi127 – 1271Copper 3By similarity
Metal bindingi468 – 4681Copper 4By similarity
Metal bindingi471 – 4711Copper 1By similarity
Metal bindingi473 – 4731Copper 3By similarity
Metal bindingi530 – 5301Copper 3By similarity
Metal bindingi531 – 5311Copper 4By similarity
Metal bindingi532 – 5321Copper 2By similarity
Metal bindingi536 – 5361Copper 4By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-23 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 23
Diphenol oxidase 23
Urishiol oxidase 23
Gene namesi
Name:LAC23
Ordered Locus Names:Os12g0108000, LOC_Os12g01730
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 12

Organism-specific databases

GrameneiQ2QYS3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 567545Laccase-23PRO_0000291910Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi76 – 761N-linked (GlcNAc...)Sequence Analysis
Glycosylationi187 – 1871N-linked (GlcNAc...)Sequence Analysis
Glycosylationi241 – 2411N-linked (GlcNAc...)Sequence Analysis
Glycosylationi298 – 2981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi312 – 3121N-linked (GlcNAc...)Sequence Analysis
Glycosylationi327 – 3271N-linked (GlcNAc...)Sequence Analysis
Glycosylationi365 – 3651N-linked (GlcNAc...)Sequence Analysis
Glycosylationi368 – 3681N-linked (GlcNAc...)Sequence Analysis
Glycosylationi378 – 3781N-linked (GlcNAc...)Sequence Analysis
Glycosylationi388 – 3881N-linked (GlcNAc...)Sequence Analysis
Glycosylationi430 – 4301N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

ExpressionAtlasiQ2QYS3. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g01730.1.

Structurei

3D structure databases

ProteinModelPortaliQ2QYS3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 146117Plastocyanin-like 1Add
BLAST
Domaini158 – 310153Plastocyanin-like 2Add
BLAST
Domaini415 – 551137Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ2QYS3.
OMAiNRGRDNV.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QYS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSRGCSCWL LSLALLCSLA AAKEQYHEFV IRETTVKRLC KSQSIMTVNG
60 70 80 90 100
QFPGPTLEIK EGDSLIINLI NRGRYNVTLH WHGVRQMRTG WSDGPEYVTQ
110 120 130 140 150
CPVRPGQSYR YRFTVAAQEG TLWWHAHSSW LRATVYGALL IRPRDGTSYP
160 170 180 190 200
FHVQPTRELA PILLGEWWDM NPVDVVRAAT RTGAAPNISD ALTVNAQPGD
210 220 230 240 250
LYSCSSHDTA FFPVTSGETN LLRFINAALN TELFVSLAGH NMTVVAADAS
260 270 280 290 300
YTKPYTTSLL LLAPGQTTDV LVTFDQPPGR YYLAARAYAS AQGVPFDNTT
310 320 330 340 350
TTAIFDYGAA NNASSAAIAM PTLPAYNDTT AATAFTTNLR GLRKAELPSR
360 370 380 390 400
VDESLFFTVG VGLFNCTNAT AQQCGGPNGT RFAASINNVS FVLPSSTSIL
410 420 430 440 450
QAHHHGAPGG VFTADFPASP PVQFDYTAQN VSRALWQPVP GTKVYKLKYG
460 470 480 490 500
SAVQVVLQGT NIFAGENHPI HLHGYDFYIL AEGLGNFDAG ADTAKFNMED
510 520 530 540 550
PPMRNTVGVP VNGWAVIRFV ADNPGVWLMH CHLDVHITWG LAMAFLVDDG
560
VGELQSLEAP PPDLPLC
Length:567
Mass (Da):61,565
Last modified:January 24, 2006 - v1
Checksum:i2507A6CBDAE29D74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA96185.1.
AP008218 Genomic DNA. Translation: BAF28967.1.
RefSeqiNP_001065948.1. NM_001072480.1.
UniGeneiOs.56166.

Genome annotation databases

EnsemblPlantsiOS12T0108000-01; OS12T0108000-01; OS12G0108000.
GeneIDi4351276.
KEGGiosa:4351276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA96185.1.
AP008218 Genomic DNA. Translation: BAF28967.1.
RefSeqiNP_001065948.1. NM_001072480.1.
UniGeneiOs.56166.

3D structure databases

ProteinModelPortaliQ2QYS3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os12g01730.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS12T0108000-01; OS12T0108000-01; OS12G0108000.
GeneIDi4351276.
KEGGiosa:4351276.

Organism-specific databases

GrameneiQ2QYS3.

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ2QYS3.
OMAiNRGRDNV.

Gene expression databases

ExpressionAtlasiQ2QYS3. baseline.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC23_ORYSJ
AccessioniPrimary (citable) accession number: Q2QYS3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: July 22, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.