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Reviewed, UniProtKB/Swiss-Prot Q2QYS3 (LAC23_ORYSJ)

Last modified November 25, 2008. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Laccase-23
    EC=1.10.3.2
Alternative name(s):
    Benzenediol:oxygen oxidoreductase 23
    Urishiol oxidase 23
    Diphenol oxidase 23
Gene names
Name: LAC23
Ordered Locus Names: Os12g0108000, LOC_Os12g01730
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

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Protein attributes

Sequence length567 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Lignin degradation and detoxification of lignin-derived products By similarity.

Catalytic activity

4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O.

Cofactor

Binds 4 copper ions per monomer By similarity.

Subcellular location

Secreted › extracellular space › apoplastPotential.

Sequence similarities

Belongs to the multicopper oxidase family.

Contains 3 plastocyanin-like domains.

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Ontologies

Keywords

   Biological processLignin degradation
   Cellular componentApoplast
Secreted
   DomainRepeat
Signal
   LigandCopper
Metal-binding
   Molecular functionOxidoreductase
   PTMGlycoprotein

Gene Ontology (GO)

   Biological processlignin catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentapoplast

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncopper ion binding

Inferred from electronic annotation. Source: InterPro

laccase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 567545Laccase-23
PRO_0000291910

Regions

Domain30 – 146117Plastocyanin-like 1
Domain158 – 310153Plastocyanin-like 2
Domain415 – 551137Plastocyanin-like 3

Sites

Metal binding801Copper 1 By similarity
Metal binding821Copper 2 By similarity
Metal binding1251Copper 2 By similarity
Metal binding1271Copper 3 By similarity
Metal binding4681Copper 4 By similarity
Metal binding4711Copper 1 By similarity
Metal binding4731Copper 3 By similarity
Metal binding5301Copper 3 By similarity
Metal binding5311Copper 4 By similarity
Metal binding5321Copper 2 By similarity
Metal binding5361Copper 4 By similarity

Amino acid modifications

Glycosylation761N-linked (GlcNAc...) Potential
Glycosylation1871N-linked (GlcNAc...) Potential
Glycosylation2411N-linked (GlcNAc...) Potential
Glycosylation2981N-linked (GlcNAc...) Potential
Glycosylation3121N-linked (GlcNAc...) Potential
Glycosylation3271N-linked (GlcNAc...) Potential
Glycosylation3651N-linked (GlcNAc...) Potential
Glycosylation3681N-linked (GlcNAc...) Potential
Glycosylation3781N-linked (GlcNAc...) Potential
Glycosylation3881N-linked (GlcNAc...) Potential
Glycosylation4301N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
Q2QYS3-1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: 2507A6CBDAE29D74

FASTA56761,565
        10         20         30         40         50         60 
MGSRGCSCWL LSLALLCSLA AAKEQYHEFV IRETTVKRLC KSQSIMTVNG QFPGPTLEIK 

        70         80         90        100        110        120 
EGDSLIINLI NRGRYNVTLH WHGVRQMRTG WSDGPEYVTQ CPVRPGQSYR YRFTVAAQEG 

       130        140        150        160        170        180 
TLWWHAHSSW LRATVYGALL IRPRDGTSYP FHVQPTRELA PILLGEWWDM NPVDVVRAAT 

       190        200        210        220        230        240 
RTGAAPNISD ALTVNAQPGD LYSCSSHDTA FFPVTSGETN LLRFINAALN TELFVSLAGH 

       250        260        270        280        290        300 
NMTVVAADAS YTKPYTTSLL LLAPGQTTDV LVTFDQPPGR YYLAARAYAS AQGVPFDNTT 

       310        320        330        340        350        360 
TTAIFDYGAA NNASSAAIAM PTLPAYNDTT AATAFTTNLR GLRKAELPSR VDESLFFTVG 

       370        380        390        400        410        420 
VGLFNCTNAT AQQCGGPNGT RFAASINNVS FVLPSSTSIL QAHHHGAPGG VFTADFPASP 

       430        440        450        460        470        480 
PVQFDYTAQN VSRALWQPVP GTKVYKLKYG SAVQVVLQGT NIFAGENHPI HLHGYDFYIL 

       490        500        510        520        530        540 
AEGLGNFDAG ADTAKFNMED PPMRNTVGVP VNGWAVIRFV ADNPGVWLMH CHLDVHITWG 

       550        560 
LAMAFLVDDG VGELQSLEAP PPDLPLC

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References

« Hide 'large scale' references
[1]"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
The rice chromosomes 11 and 12 sequencing consortia
BMC Biol. 3:20-20(2005) [PubMed: 16188032] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed: 16100779] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana."
The rice annotation project (RAP)
Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.

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Cross-references

Sequence databases

DP000011 Genomic DNA. Translation: ABA96185.1.
AP008218 Genomic DNA. Translation: BAF28967.1.
RefSeqNP_001065948.1.
UniGeneOs.56166

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4351276.
KEGGosa:4351276.

Organism-specific databases

GrameneQ2QYS3.

Family and domain databases

InterProIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
Gene3DG3DSA:2.60.40.420. Cupredoxin. 3 hits.
PfamPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
PROSITEPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameLAC23_ORYSJ
AccessionPrimary (citable) accession number: Q2QYS3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: November 25, 2008
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents