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Protein

Laccase-23

Gene

LAC23

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi80Copper 1By similarity1
Metal bindingi82Copper 2By similarity1
Metal bindingi125Copper 2By similarity1
Metal bindingi127Copper 3By similarity1
Metal bindingi468Copper 4By similarity1
Metal bindingi471Copper 1By similarity1
Metal bindingi473Copper 3By similarity1
Metal bindingi530Copper 3By similarity1
Metal bindingi531Copper 4By similarity1
Metal bindingi532Copper 2By similarity1
Metal bindingi536Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-23 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 23
Diphenol oxidase 23
Urishiol oxidase 23
Gene namesi
Name:LAC23
Ordered Locus Names:Os12g0108000, LOC_Os12g01730
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 12

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000029191023 – 567Laccase-23Add BLAST545

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi76N-linked (GlcNAc...)Sequence analysis1
Glycosylationi187N-linked (GlcNAc...)Sequence analysis1
Glycosylationi241N-linked (GlcNAc...)Sequence analysis1
Glycosylationi298N-linked (GlcNAc...)Sequence analysis1
Glycosylationi312N-linked (GlcNAc...)Sequence analysis1
Glycosylationi327N-linked (GlcNAc...)Sequence analysis1
Glycosylationi365N-linked (GlcNAc...)Sequence analysis1
Glycosylationi368N-linked (GlcNAc...)Sequence analysis1
Glycosylationi378N-linked (GlcNAc...)Sequence analysis1
Glycosylationi388N-linked (GlcNAc...)Sequence analysis1
Glycosylationi430N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ2QYS3.

Expressioni

Gene expression databases

GenevisibleiQ2QYS3. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g01730.1.

Structurei

3D structure databases

ProteinModelPortaliQ2QYS3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 146Plastocyanin-like 1Add BLAST117
Domaini158 – 310Plastocyanin-like 2Add BLAST153
Domaini415 – 551Plastocyanin-like 3Add BLAST137

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ2QYS3.
OMAiMEDPPMR.
OrthoDBiEOG093605O6.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QYS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSRGCSCWL LSLALLCSLA AAKEQYHEFV IRETTVKRLC KSQSIMTVNG
60 70 80 90 100
QFPGPTLEIK EGDSLIINLI NRGRYNVTLH WHGVRQMRTG WSDGPEYVTQ
110 120 130 140 150
CPVRPGQSYR YRFTVAAQEG TLWWHAHSSW LRATVYGALL IRPRDGTSYP
160 170 180 190 200
FHVQPTRELA PILLGEWWDM NPVDVVRAAT RTGAAPNISD ALTVNAQPGD
210 220 230 240 250
LYSCSSHDTA FFPVTSGETN LLRFINAALN TELFVSLAGH NMTVVAADAS
260 270 280 290 300
YTKPYTTSLL LLAPGQTTDV LVTFDQPPGR YYLAARAYAS AQGVPFDNTT
310 320 330 340 350
TTAIFDYGAA NNASSAAIAM PTLPAYNDTT AATAFTTNLR GLRKAELPSR
360 370 380 390 400
VDESLFFTVG VGLFNCTNAT AQQCGGPNGT RFAASINNVS FVLPSSTSIL
410 420 430 440 450
QAHHHGAPGG VFTADFPASP PVQFDYTAQN VSRALWQPVP GTKVYKLKYG
460 470 480 490 500
SAVQVVLQGT NIFAGENHPI HLHGYDFYIL AEGLGNFDAG ADTAKFNMED
510 520 530 540 550
PPMRNTVGVP VNGWAVIRFV ADNPGVWLMH CHLDVHITWG LAMAFLVDDG
560
VGELQSLEAP PPDLPLC
Length:567
Mass (Da):61,565
Last modified:January 24, 2006 - v1
Checksum:i2507A6CBDAE29D74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA96185.1.
AP008218 Genomic DNA. Translation: BAF28967.1.
AP014968 Genomic DNA. Translation: BAT15521.1.
RefSeqiXP_015619028.1. XM_015763542.1.
UniGeneiOs.56166.

Genome annotation databases

EnsemblPlantsiOS12T0108000-01; OS12T0108000-01; OS12G0108000.
GeneIDi4351276.
GrameneiOS12T0108000-01; OS12T0108000-01; OS12G0108000.
KEGGiosa:4351276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA96185.1.
AP008218 Genomic DNA. Translation: BAF28967.1.
AP014968 Genomic DNA. Translation: BAT15521.1.
RefSeqiXP_015619028.1. XM_015763542.1.
UniGeneiOs.56166.

3D structure databases

ProteinModelPortaliQ2QYS3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os12g01730.1.

Proteomic databases

PaxDbiQ2QYS3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS12T0108000-01; OS12T0108000-01; OS12G0108000.
GeneIDi4351276.
GrameneiOS12T0108000-01; OS12T0108000-01; OS12G0108000.
KEGGiosa:4351276.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ2QYS3.
OMAiMEDPPMR.
OrthoDBiEOG093605O6.

Gene expression databases

GenevisibleiQ2QYS3. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC23_ORYSJ
AccessioniPrimary (citable) accession number: Q2QYS3
Secondary accession number(s): A0A0P0Y608
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: November 30, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.