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Protein

Probable apyrase 3

Gene

APY3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.By similarity

Catalytic activityi

A nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate.

Cofactori

Ca2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei169Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi47 – 57ATP-bindingCuratedAdd BLAST11
Nucleotide bindingi193 – 203ATP-bindingCuratedAdd BLAST11

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandATP-binding, Calcium, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-8850843. Phosphate bond hydrolysis by NTPDase proteins.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable apyrase 3 (EC:3.6.1.5)
Short name:
OsAPY3
Alternative name(s):
ATP-diphosphatase
ATP-diphosphohydrolase
Adenosine diphosphatase
Short name:
ADPase
Gene namesi
Name:APY3
Ordered Locus Names:Os12g0123500, LOC_Os12g02980
ORF Names:OsJ_35056
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000041990923 – 451Probable apyrase 3Add BLAST429

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi275N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi315N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ2QYE1.
PRIDEiQ2QYE1.

Expressioni

Gene expression databases

GenevisibleiQ2QYE1. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g02980.1.

Structurei

3D structure databases

SMRiQ2QYE1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GDA1/CD39 NTPase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG1385. Eukaryota.
COG5371. LUCA.
InParanoidiQ2QYE1.
OMAiKARDHAY.
OrthoDBiEOG09360CC7.

Family and domain databases

InterProiView protein in InterPro
IPR000407. GDA1_CD39_NTPase.
PANTHERiPTHR11782. PTHR11782. 1 hit.
PfamiView protein in Pfam
PF01150. GDA1_CD39. 1 hit.
PROSITEiView protein in PROSITE
PS01238. GDA1_CD39_NTPASE. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QYE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAADHLVVAM LLLLALSPPA VADDTAVLGR KGGVVEGQAA GPGRYAVILD
60 70 80 90 100
AGSTGTRVHV FRFDNKLDLL KVGDNIELFA KVDPGLSSYA GRPQDAANSI
110 120 130 140 150
LPLLDKANTV VPARLMNKTP LKLGATAGLR LIGDEKANQI LEAVRDVVHT
160 170 180 190 200
KSKYQYNPNW INVLEGSQEG SYIWVALNYL LDKLGGDYSK TVGVVDLGGG
210 220 230 240 250
SVQMAYAISS NTAATAPKVP EGKDPYVVKE YLKGKDYNIY VHSYLHYGGF
260 270 280 290 300
ASRAHILERK DGPFSNCMLR GFSGNFTYNG KQYDATAAPQ GADYHKCREE
310 320 330 340 350
VVKLLKVNAP CETKNCSFNG VWNGGGGAGQ DDLYVASAFY YIASHVGFIN
360 370 380 390 400
SDAPSAKSTP ATFKAVAEKV CKLSVKEAKV EYPNVRDHAY LCMDLIYEYS
410 420 430 440 450
LLVDGFGLHP SKEITLVDKV KHGEYYIDAA WPLGTAIEAV SPKKRLREIY

K
Length:451
Mass (Da):48,901
Last modified:July 11, 2006 - v2
Checksum:iA4DCE9410897E241
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti225P → S in AK072692 (PubMed:12869764).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA95698.2.
AP008218 Genomic DNA. Translation: BAF29051.1.
AP014968 Genomic DNA. Translation: BAT15669.1.
CM000149 Genomic DNA. Translation: EEE52674.1.
AK072692 mRNA. No translation available.
UniGeneiOs.11718.

Genome annotation databases

EnsemblPlantsiOS12T0123500-01; OS12T0123500-01; OS12G0123500.
GrameneiOS12T0123500-01; OS12T0123500-01; OS12G0123500.

Similar proteinsi

Entry informationi

Entry nameiAPY3_ORYSJ
AccessioniPrimary (citable) accession number: Q2QYE1
Secondary accession number(s): A0A0P0Y6G6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2012
Last sequence update: July 11, 2006
Last modified: October 25, 2017
This is version 80 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families