ID   DPNP_ORYSJ              Reviewed;         358 AA.
AC   Q2QWT4; Q40639;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   16-JUN-2009, entry version 25.
DE   RecName: Full=3'(2'),5'-bisphosphate nucleotidase;
DE            EC=3.1.3.7;
DE   AltName: Full=3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase;
DE   AltName: Full=DPNPase;
GN   OrderedLocusNames=Os12g0183300, LOC_Os12g08280;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease
RT   resistance genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=17210932; DOI=10.1101/gr.5509507;
RG   The rice annotation project (RAP);
RT   "Curated genome annotation of Oryza sativa ssp. japonica and
RT   comparative genome analysis with Arabidopsis thaliana.";
RL   Genome Res. 17:175-183(2007).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 159-358.
RC   STRAIN=cv. Nipponbare;
RX   MEDLINE=22752273; PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- FUNCTION: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS)
CC       to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine
CC       5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the
CC       sulfur-activation pathway by converting PAPS to APS (By
CC       similarity).
CC   -!- CATALYTIC ACTIVITY: Adenosine 3',5'-bisphosphate + H(2)O =
CC       adenosine 5'-phosphate + phosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- ENZYME REGULATION: Inhibited by Ca(2+), Li(+), and Na(+) and
CC       activated by K(+) (By similarity).
CC   -!- SIMILARITY: Belongs to the inositol monophosphatase family.
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DR   EMBL; DP000011; ABA95973.1; -; Genomic_DNA.
DR   EMBL; AP008218; BAF29345.1; -; Genomic_DNA.
DR   EMBL; AK058937; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001066326.1; -.
DR   UniGene; Os.37640; -.
DR   HSSP; P32179; 1KA1.
DR   GeneID; 4351686; -.
DR   KEGG; osa:4351686; -.
DR   Gramene; Q2QWT4; -.
DR   GO; GO:0008441; F:3'(2'),5'-bisphosphate nucleotidase activity; IEA:EC.
DR   GO; GO:0004437; F:inositol or phosphatidylinositol phosphatas...; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006790; P:sulfur metabolic process; IEA:InterPro.
DR   InterPro; IPR006239; Bisphos_HAL2.
DR   InterPro; IPR000760; Inositol_P.
DR   PANTHER; PTHR20854; Inositol_P; 1.
DR   Pfam; PF00459; Inositol_P; 1.
DR   PRINTS; PR00378; INOSPHPHTASE.
DR   ProDom; PD023420; Inositol_P; 1.
DR   TIGRFAMs; TIGR01330; bisphos_HAL2; 1.
DR   PROSITE; PS00629; IMP_1; 1.
DR   PROSITE; PS00630; IMP_2; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Magnesium; Metal-binding.
FT   CHAIN         1    358       3'(2'),5'-bisphosphate nucleotidase.
FT                                /FTId=PRO_0000142535.
FT   METAL        78     78       Magnesium 1 (By similarity).
FT   METAL       140    140       Magnesium 1 (By similarity).
FT   METAL       140    140       Magnesium 2 (By similarity).
FT   METAL       142    142       Magnesium 1; via carbonyl oxygen (By
FT                                similarity).
FT   METAL       143    143       Magnesium 2 (By similarity).
FT   METAL       292    292       Magnesium 2 (By similarity).
SQ   SEQUENCE   358 AA;  37480 MW;  EFE813C18BEDB5FD CRC64;
     MSQAAGNPYA AELAAAKKAV TLAARLCQAV QKDILQSGVQ SKADQSPVTV ADYGSQILVS
     LVLKMEAPAS SSFSMVAEED SEELRKEGAE EILENITELV NETIVDDGTY SIYFSKEGIL
     SAIDDGKSEG GPSGRHWVLD PIDGTKGFLR GDQYAIALAL LDEGKVVLGV LACPNLSLGS
     IGNLNGGSSG DQVGALFSAT IGCGAEVESL QGSPAQKISV CSIDNPVEAS FFESYEGAHS
     LRDLTGSIAE KLGVQAPPVR IDSQAKYGAL ARGDGAIYLR FPHKGYREKI WDHAAGSIVV
     TEAGGLVTDA SGNDLDFSKG RFLDLDTGII ATNKQLMPSL LKAVQDAIKE QNQAASPL
//