Q2QWE3 (P2C77_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 77
Short name=OsPP2C77
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os12g0198200, LOC_Os12g09640
ORF Names:	OsJ_034145

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	421 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 421	421	Probable protein phosphatase 2C 77		PRO_0000363324
Regions
	Domain	136 – 408	273	PP2C-like
	Compositional bias	63 – 69	7	Poly-Pro
Sites
	Metal binding	175	1	Manganese 1 By similarity
	Metal binding	175	1	Manganese 2 By similarity
	Metal binding	176	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	360	1	Manganese 2 By similarity
	Metal binding	406	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2QWE3 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: F59478DD84F147CA	FASTA	421	43,557
	10 20 30 40 50 60 MLCGVEILCS VVAVVARVLG RALMTICSPK FSTAGLIGSP TTAWGGGGAK KKVHMESEKQ 70 80 90 100 110 120 QLPPPPSPPA LVLPAFKRNC TDQEQRAPAT STKAARGRPP RLVIPAAAPV AVARGGVDPF 130 140 150 160 170 180 GGRETDVATE TEVKGEGFCL ASRRGVRHAM EDGYGVITRH KIEGGSQLAF YGVYDGHGGR 190 200 210 220 230 240 AAVDFVADKL GKNVVTAAAA ATTMSRHQAA GSSSPSQQRR EEEDDVTAAI RAAYLTTDSE 250 260 270 280 290 300 FLSQGVRGGA CAATALVKDG ELYVSNVGDC RAVLGSRGGV ATALTSDHTP GREDERLRIE 310 320 330 340 350 360 STGGYVSCGG SGVWRVQDSL AVSRAFGDAG VKQWVTCEPE TARVSLAADG DCRFLVLASD 370 380 390 400 410 420 GLWCKVSNQE AVDAVAAAAA AAAGVAGSTD PCKELAAMAR SRGSRDDITV MVVDLQPFLP V

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." The rice chromosomes 11 and 12 sequencing consortia BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"The genomes of Oryza sativa: a history of duplications." Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H. PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DP000011 Genomic DNA. Translation: ABA96661.1. AP008218 Genomic DNA. Translation: BAF29383.1. CM000149 Genomic DNA. No translation available.
RefSeq	NP_001066364.1. NM_001072896.1.
UniGene	Os.74554.
3D structure databases
ProteinModelPortal	Q2QWE3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os12g09640.1; LOC_Os12g09640.1; LOC_Os12g09640.
GeneID	4351729.
KEGG	osa:4351729.
Organism-specific databases
Gramene	Q2QWE3.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
OMA	VRHAMED.
ProtClustDB	CLSN2698791.
Gene expression databases
ArrayExpress	Q2QWE3.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C77_ORYSJ

Accession

Primary (citable) accession number: Q2QWE3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	January 24, 2006
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program