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Protein

Laccase-24

Gene

LAC24

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi82Copper 1By similarity1
Metal bindingi84Copper 2By similarity1
Metal bindingi127Copper 2By similarity1
Metal bindingi129Copper 3By similarity1
Metal bindingi480Copper 4By similarity1
Metal bindingi483Copper 1By similarity1
Metal bindingi485Copper 3By similarity1
Metal bindingi542Copper 3By similarity1
Metal bindingi543Copper 4By similarity1
Metal bindingi544Copper 2By similarity1
Metal bindingi548Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-24 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 24
Diphenol oxidase 24
Urishiol oxidase 24
Gene namesi
Name:LAC24
Ordered Locus Names:Os12g0258700, LOC_Os12g15680
ORF Names:OsJ_016843, OsJ_17624
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 12

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000029191124 – 579Laccase-24Add BLAST556

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi34N-linked (GlcNAc...)Sequence analysis1
Glycosylationi78N-linked (GlcNAc...)Sequence analysis1
Glycosylationi110N-linked (GlcNAc...)Sequence analysis1
Glycosylationi116N-linked (GlcNAc...)Sequence analysis1
Glycosylationi204N-linked (GlcNAc...)Sequence analysis1
Glycosylationi209N-linked (GlcNAc...)Sequence analysis1
Glycosylationi219N-linked (GlcNAc...)Sequence analysis1
Glycosylationi241N-linked (GlcNAc...)Sequence analysis1
Glycosylationi312N-linked (GlcNAc...)Sequence analysis1
Glycosylationi337N-linked (GlcNAc...)Sequence analysis1
Glycosylationi348N-linked (GlcNAc...)Sequence analysis1
Glycosylationi398N-linked (GlcNAc...)Sequence analysis1
Glycosylationi405N-linked (GlcNAc...)Sequence analysis1
Glycosylationi444N-linked (GlcNAc...)Sequence analysis1
Glycosylationi462N-linked (GlcNAc...)Sequence analysis1
Glycosylationi500N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ2QUN2.

Expressioni

Gene expression databases

GenevisibleiQ2QUN2. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g15680.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 148Plastocyanin-like 1Add BLAST118
Domaini159 – 322Plastocyanin-like 2Add BLAST164
Domaini425 – 563Plastocyanin-like 3Add BLAST139

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ2QUN2.
KOiK05909.
OrthoDBiEOG093605LR.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 5 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QUN2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARSWSLLLL PFALALVASV AQAAVVEYTF NVGNLSISQL CQQEMIITAV
60 70 80 90 100
NGQLPGPTIV ATEGDTVVVH MVNESPYNMT IHWHGIFQRG TPWADGPAMV
110 120 130 140 150
TQCPVRPGGN YTYRFNVTGQ EGTLWWHSHF SFLRATVYGA LIIKPRGGAK
160 170 180 190 200
AYPFPVPDEE VVVILGEWWK TNVYDLQQRS LVTGNPAPHA DAYTINGKPG
210 220 230 240 250
DFYNCSAPNQ THKFELKQNK TYMLRIINAA LNTPLFFKVA NHSFNVVAAD
260 270 280 290 300
ACYTKPYKTD VVVISPGQTV DALLVPDAGV AAAVGGRYYM AVIPYNSAVN
310 320 330 340 350
AADPSFLYSL TNSTAIVEYG GGPATSPPMV PDMPEYNDTA TAHRFLSNMT
360 370 380 390 400
ALVPNRVPLA VDTHMFVTVS MGDTFCGPEQ TMCMPDDKGT IFASSMNNAS
410 420 430 440 450
FILPNTTSML EAMYKGSIDG VYTRDFPDTP PIVFDYTADA SDDNATLKHT
460 470 480 490 500
FKSTKVKTLK YNSTVQMVLQ NTRLVSKESH PMHLHGFNFF VLAQGFGNYN
510 520 530 540 550
ETTDPAKFNL VDPQERNTVA VPTGGWAVIR FVADNPGVWF MHCHFDAHLE
560 570
FGLGMVFEVQ NGPTQETSLP PPPSDLPQC
Length:579
Mass (Da):63,459
Last modified:January 24, 2006 - v1
Checksum:iFD10AEC0CC9EB013
GO

Sequence cautioni

The sequence BAH01413 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA97304.1.
AP008218 Genomic DNA. Translation: BAF29536.2.
AP014968 Genomic DNA. No translation available.
CM000142 Genomic DNA. Translation: EEE62821.1.
AK243030 mRNA. Translation: BAH01413.1. Different initiation.
RefSeqiXP_015618619.1. XM_015763133.1.
UniGeneiOs.78609.

Genome annotation databases

GeneIDi4351915.
KEGGiosa:4351915.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA97304.1.
AP008218 Genomic DNA. Translation: BAF29536.2.
AP014968 Genomic DNA. No translation available.
CM000142 Genomic DNA. Translation: EEE62821.1.
AK243030 mRNA. Translation: BAH01413.1. Different initiation.
RefSeqiXP_015618619.1. XM_015763133.1.
UniGeneiOs.78609.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os12g15680.1.

Proteomic databases

PaxDbiQ2QUN2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4351915.
KEGGiosa:4351915.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ2QUN2.
KOiK05909.
OrthoDBiEOG093605LR.

Gene expression databases

GenevisibleiQ2QUN2. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 5 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC24_ORYSJ
AccessioniPrimary (citable) accession number: Q2QUN2
Secondary accession number(s): B7F9W5, B9FJ53, Q0IP29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: November 30, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.