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Q2QUN2

- LAC24_ORYSJ

UniProt

Q2QUN2 - LAC24_ORYSJ

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Protein

Laccase-24

Gene

LAC24

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi82 – 821Copper 1By similarity
Metal bindingi84 – 841Copper 2By similarity
Metal bindingi127 – 1271Copper 2By similarity
Metal bindingi129 – 1291Copper 3By similarity
Metal bindingi480 – 4801Copper 4By similarity
Metal bindingi483 – 4831Copper 1By similarity
Metal bindingi485 – 4851Copper 3By similarity
Metal bindingi542 – 5421Copper 3By similarity
Metal bindingi543 – 5431Copper 4By similarity
Metal bindingi544 – 5441Copper 2By similarity
Metal bindingi548 – 5481Copper 4By similarity

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-24 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 24
Diphenol oxidase 24
Urishiol oxidase 24
Gene namesi
Name:LAC24
Ordered Locus Names:Os12g0258700, LOC_Os12g15680
ORF Names:OsJ_016843, OsJ_17624
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 12

Organism-specific databases

GrameneiQ2QUN2.

Subcellular locationi

GO - Cellular componenti

  1. apoplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 579556Laccase-24PRO_0000291911Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi34 – 341N-linked (GlcNAc...)Sequence Analysis
Glycosylationi78 – 781N-linked (GlcNAc...)Sequence Analysis
Glycosylationi110 – 1101N-linked (GlcNAc...)Sequence Analysis
Glycosylationi116 – 1161N-linked (GlcNAc...)Sequence Analysis
Glycosylationi204 – 2041N-linked (GlcNAc...)Sequence Analysis
Glycosylationi209 – 2091N-linked (GlcNAc...)Sequence Analysis
Glycosylationi219 – 2191N-linked (GlcNAc...)Sequence Analysis
Glycosylationi241 – 2411N-linked (GlcNAc...)Sequence Analysis
Glycosylationi312 – 3121N-linked (GlcNAc...)Sequence Analysis
Glycosylationi337 – 3371N-linked (GlcNAc...)Sequence Analysis
Glycosylationi348 – 3481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi398 – 3981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi405 – 4051N-linked (GlcNAc...)Sequence Analysis
Glycosylationi444 – 4441N-linked (GlcNAc...)Sequence Analysis
Glycosylationi462 – 4621N-linked (GlcNAc...)Sequence Analysis
Glycosylationi500 – 5001N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os12g15680.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 148118Plastocyanin-like 1Add
BLAST
Domaini159 – 322164Plastocyanin-like 2Add
BLAST
Domaini425 – 563139Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ2QUN2.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 5 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q2QUN2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARSWSLLLL PFALALVASV AQAAVVEYTF NVGNLSISQL CQQEMIITAV
60 70 80 90 100
NGQLPGPTIV ATEGDTVVVH MVNESPYNMT IHWHGIFQRG TPWADGPAMV
110 120 130 140 150
TQCPVRPGGN YTYRFNVTGQ EGTLWWHSHF SFLRATVYGA LIIKPRGGAK
160 170 180 190 200
AYPFPVPDEE VVVILGEWWK TNVYDLQQRS LVTGNPAPHA DAYTINGKPG
210 220 230 240 250
DFYNCSAPNQ THKFELKQNK TYMLRIINAA LNTPLFFKVA NHSFNVVAAD
260 270 280 290 300
ACYTKPYKTD VVVISPGQTV DALLVPDAGV AAAVGGRYYM AVIPYNSAVN
310 320 330 340 350
AADPSFLYSL TNSTAIVEYG GGPATSPPMV PDMPEYNDTA TAHRFLSNMT
360 370 380 390 400
ALVPNRVPLA VDTHMFVTVS MGDTFCGPEQ TMCMPDDKGT IFASSMNNAS
410 420 430 440 450
FILPNTTSML EAMYKGSIDG VYTRDFPDTP PIVFDYTADA SDDNATLKHT
460 470 480 490 500
FKSTKVKTLK YNSTVQMVLQ NTRLVSKESH PMHLHGFNFF VLAQGFGNYN
510 520 530 540 550
ETTDPAKFNL VDPQERNTVA VPTGGWAVIR FVADNPGVWF MHCHFDAHLE
560 570
FGLGMVFEVQ NGPTQETSLP PPPSDLPQC
Length:579
Mass (Da):63,459
Last modified:January 24, 2006 - v1
Checksum:iFD10AEC0CC9EB013
GO

Sequence cautioni

The sequence BAH01413.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA97304.1.
AP008218 Genomic DNA. Translation: BAF29536.2.
CM000142 Genomic DNA. Translation: EEE62821.1.
AK243030 mRNA. Translation: BAH01413.1. Different initiation.
RefSeqiNP_001066517.2. NM_001073049.2.
UniGeneiOs.78609.

Genome annotation databases

GeneIDi4351915.
KEGGiosa:4351915.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DP000011 Genomic DNA. Translation: ABA97304.1 .
AP008218 Genomic DNA. Translation: BAF29536.2 .
CM000142 Genomic DNA. Translation: EEE62821.1 .
AK243030 mRNA. Translation: BAH01413.1 . Different initiation.
RefSeqi NP_001066517.2. NM_001073049.2.
UniGenei Os.78609.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 39947.LOC_Os12g15680.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4351915.
KEGGi osa:4351915.

Organism-specific databases

Gramenei Q2QUN2.

Phylogenomic databases

eggNOGi COG2132.
HOGENOMi HOG000241916.
InParanoidi Q2QUN2.

Family and domain databases

Gene3Di 2.60.40.420. 3 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 5 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  5. "Oryza sativa full-length cDNA."
    The rice full-length cDNA consortium
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC24_ORYSJ
AccessioniPrimary (citable) accession number: Q2QUN2
Secondary accession number(s): B7F9W5, B9FJ53, Q0IP29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 24, 2006
Last modified: November 26, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3