Q2QSL4 (CDKF2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative cyclin-dependent kinase F-2
Short name=CDKF;2
EC=2.7.11.22
EC=2.7.11.23

Gene names

Name:	CDKF-2
Ordered Locus Names:	Os12g0424700, LOC_Os12g23700

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Sequence similarities	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. Contains 1 protein kinase domain.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell cycle Inferred from electronic annotation. Source: GOC
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW RNA polymerase II carboxy-terminal domain kinase activity Inferred from electronic annotation. Source: EC cyclin-dependent protein serine/threonine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 327	327	Putative cyclin-dependent kinase F-2		PRO_0000296107
Regions
	Domain	4 – 295	292	Protein kinase
	Nucleotide binding	10 – 18	9	ATP By similarity
Sites
	Active site	134	1	Proton acceptor By similarity
	Binding site	33	1	ATP By similarity
Amino acid modifications
	Modified residue	167	1	Phosphothreonine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2QSL4 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 0E78BEED04266316	FASTA	327	35,622
	10 20 30 40 50 60 MERYECLGKI GEGAAGVVHV ARDRTTGETV AVKRLHGGIG CGEEEWLREA RCLQACRGHP 70 80 90 100 110 120 HLVELRAAHR EMRRGGGGAC CYVVMEYVDG PSLSRVVREE RRGRPFPEAE ARRLMRQLLD 130 140 150 160 170 180 GVAAMHAAGV MHRDLKPDNV VVGPRGDLKI CDFGMSRVTA AGAPPYTSPV VTLWYRAPEL 190 200 210 220 230 240 ILGSQEYDSL VDTWSLGCIM AELLAGAPLF PGRSEMDQLN RVFDTVGMQD MKSWPGFARL 250 260 270 280 290 300 PRAESALCSR ARPPSRLREM FPKLSAAGFD VLSGLLACRP DRRLTAADAL RCAWFTEADT 310 320 PPDATPVTCG SARFTPCVSG VADAIVV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." The rice chromosomes 11 and 12 sequencing consortia BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Genome-wide identification and expression analysis of rice cell cycle genes." Guo J., Song J., Wang F., Zhang X.S. Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DP000011 Genomic DNA. Translation: ABA97935.1. AP008218 Genomic DNA. Translation: BAF29682.1.
RefSeq	NP_001066663.1. NM_001073195.1.
UniGene	Os.86184.
3D structure databases
HSSP	HSSP built from PDB template 2BTR based on UniProtKB P24941.
ProteinModelPortal	Q2QSL4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os12g23700.1; LOC_Os12g23700.1; LOC_Os12g23700.
GeneID	4352099.
KEGG	osa:4352099.
Organism-specific databases
Gramene	Q2QSL4.
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000233024.
KO	K08818.
OMA	GRSEMDQ.
ProtClustDB	CLSN2698852.
Gene expression databases
ArrayExpress	Q2QSL4.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002290. Ser/Thr_dual-sp_kinase_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CDKF2_ORYSJ

Accession

Primary (citable) accession number: Q2QSL4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	January 24, 2006
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program