UniProtKB - Q2QSL4 (CDKF2_ORYSJ)
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Protein
Putative cyclin-dependent kinase F-2
Gene
CDKF-2
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Catalytic activityi
ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 33 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 134 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 10 – 18 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- cyclin-dependent protein kinase activating kinase activity Source: GO_Central
- cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
- RNA polymerase II carboxy-terminal domain kinase activity Source: UniProtKB-EC
GO - Biological processi
- positive regulation of cyclin-dependent protein kinase activity Source: GO_Central
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CDKF-2 Ordered Locus Names:Os12g0424700, LOC_Os12g23700 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000296107 | 1 – 327 | Putative cyclin-dependent kinase F-2Add BLAST | 327 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 167 | PhosphothreonineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q2QSL4. |
Expressioni
Gene expression databases
ExpressionAtlasi | Q2QSL4. baseline and differential. |
Genevisiblei | Q2QSL4. OS. |
Structurei
3D structure databases
ProteinModelPortali | Q2QSL4. |
SMRi | Q2QSL4. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 295 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 292 |
Sequence similaritiesi
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.Curated
Phylogenomic databases
eggNOGi | KOG0663. Eukaryota. ENOG410XQ50. LUCA. |
HOGENOMi | HOG000233024. |
InParanoidi | Q2QSL4. |
KOi | K08818. |
OMAi | CEQTVLN. |
OrthoDBi | EOG09360E79. |
Family and domain databases
InterProi | View protein in InterPro IPR011009. Kinase-like_dom_sf. IPR000719. Prot_kinase_dom. IPR008271. Ser/Thr_kinase_AS. |
Pfami | View protein in Pfam PF00069. Pkinase. 1 hit. |
SMARTi | View protein in SMART SM00220. S_TKc. 1 hit. |
SUPFAMi | SSF56112. SSF56112. 1 hit. |
PROSITEi | View protein in PROSITE PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q2QSL4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERYECLGKI GEGAAGVVHV ARDRTTGETV AVKRLHGGIG CGEEEWLREA
60 70 80 90 100
RCLQACRGHP HLVELRAAHR EMRRGGGGAC CYVVMEYVDG PSLSRVVREE
110 120 130 140 150
RRGRPFPEAE ARRLMRQLLD GVAAMHAAGV MHRDLKPDNV VVGPRGDLKI
160 170 180 190 200
CDFGMSRVTA AGAPPYTSPV VTLWYRAPEL ILGSQEYDSL VDTWSLGCIM
210 220 230 240 250
AELLAGAPLF PGRSEMDQLN RVFDTVGMQD MKSWPGFARL PRAESALCSR
260 270 280 290 300
ARPPSRLREM FPKLSAAGFD VLSGLLACRP DRRLTAADAL RCAWFTEADT
310 320
PPDATPVTCG SARFTPCVSG VADAIVV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DP000011 Genomic DNA. Translation: ABA97935.1. AP008218 Genomic DNA. Translation: BAF29682.1. AP014968 Genomic DNA. Translation: BAT16911.1. |
RefSeqi | XP_015619021.1. XM_015763535.1. |
Genome annotation databases
EnsemblPlantsi | Os12t0424700-00; Os12t0424700-00; Os12g0424700. |
GeneIDi | 4352099. |
Gramenei | Os12t0424700-00; Os12t0424700-00; Os12g0424700. |
KEGGi | osa:4352099. |
Similar proteinsi
Entry informationi
Entry namei | CDKF2_ORYSJ | |
Accessioni | Q2QSL4Primary (citable) accession number: Q2QSL4 Secondary accession number(s): A0A0P0Y9N4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 24, 2007 |
Last sequence update: | January 24, 2006 | |
Last modified: | February 28, 2018 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |