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Protein

Metallothionein-like protein 4C

Gene

MT4C

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable). Acts as reactive oxygen species (ROS) scavenger. Possesses superoxide anion and hydroxyl radical scavenging activities in vitro. Involved in ROS homeostasis during anther and pollen development (PubMed:21297036).Curated1 Publication

GO - Molecular functioni

GO - Biological processi

  • pollen development Source: UniProtKB
  • reactive oxygen species metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Stress response

Keywords - Ligandi

Metal-binding, Metal-thiolate cluster

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein-like protein 4C
Alternative name(s):
Class I metallothionein-like protein 4C
MT-1-4b1 Publication
OsMT-I-4c
OsMT1c
Gene namesi
Name:MT4C
Ordered Locus Names:Os12g0571100, LOC_Os12g38300
ORF Names:OsJ_36585Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 12

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002630611 – 78Metallothionein-like protein 4CAdd BLAST78

Expressioni

Tissue specificityi

Highly expressed in roots (PubMed:21297036). Expressed in leaves, rachis, inflorescences and seeds (PubMed:17002881).2 Publications

Developmental stagei

During anther development, expressed from stage 8 to stage 12.1 Publication

Gene expression databases

GenevisibleiQ2QNC3. OS.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiQ2QNC3.
OMAiCGNNCNC.
OrthoDBiEOG0936118M.

Family and domain databases

InterProiIPR000347. Metalthion_15p.
[Graphical view]
PfamiPF01439. Metallothio_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2QNC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCGGSCNCG SCGCGGGCGK MYPDLAEKIT TTTTTATTVL GVAPEKGHSE
60 70
GVGKAAESGE AAHGCSCGSS CRCNPCNC
Length:78
Mass (Da):7,514
Last modified:January 24, 2006 - v1
Checksum:i0AF2B6CBEBC51E13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BE039221 mRNA. No translation available.
DP000011 Genomic DNA. Translation: ABA99661.1.
AP008218 Genomic DNA. Translation: BAF30102.1.
AP014968 Genomic DNA. Translation: BAT17739.1.
CM000149 Genomic DNA. Translation: EEE53461.1.
AK105219 mRNA. Translation: BAG97141.1.
RefSeqiXP_015620236.1. XM_015764750.1.
UniGeneiOs.37783.
Os.57928.

Genome annotation databases

EnsemblPlantsiOS12T0571100-01; OS12T0571100-01; OS12G0571100.
GeneIDi4352582.
GrameneiOS12T0571100-01; OS12T0571100-01; OS12G0571100.
KEGGiosa:4352582.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BE039221 mRNA. No translation available.
DP000011 Genomic DNA. Translation: ABA99661.1.
AP008218 Genomic DNA. Translation: BAF30102.1.
AP014968 Genomic DNA. Translation: BAT17739.1.
CM000149 Genomic DNA. Translation: EEE53461.1.
AK105219 mRNA. Translation: BAG97141.1.
RefSeqiXP_015620236.1. XM_015764750.1.
UniGeneiOs.37783.
Os.57928.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS12T0571100-01; OS12T0571100-01; OS12G0571100.
GeneIDi4352582.
GrameneiOS12T0571100-01; OS12T0571100-01; OS12G0571100.
KEGGiosa:4352582.

Phylogenomic databases

InParanoidiQ2QNC3.
OMAiCGNNCNC.
OrthoDBiEOG0936118M.

Gene expression databases

GenevisibleiQ2QNC3. OS.

Family and domain databases

InterProiIPR000347. Metalthion_15p.
[Graphical view]
PfamiPF01439. Metallothio_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMT4C_ORYSJ
AccessioniPrimary (citable) accession number: Q2QNC3
Secondary accession number(s): B7EXP4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: January 24, 2006
Last modified: November 30, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Plants silencing MT4C show decreased pollen fertility and increased level of superoxide anion.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Metallothioneins
    Classification of metallothioneins and list of entries
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.