Q2QN36 (P2C78_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 78
Short name=OsPP2C78
EC=3.1.3.16

Gene names

Ordered Locus Names:

Os12g0580900, LOC_Os12g39120

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 392	392	Probable protein phosphatase 2C 78		PRO_0000363325
Regions
	Domain	33 – 314	282	PP2C-like
	Compositional bias	15 – 28	14	Poly-Gly
Sites
	Metal binding	73	1	Manganese 1 By similarity
	Metal binding	73	1	Manganese 2 By similarity
	Metal binding	74	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	274	1	Manganese 2 By similarity
	Metal binding	333	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2QN36 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: 6625DD5DE8495B8F	FASTA	392	43,529
	10 20 30 40 50 60 MLLRWLARPA ERCLGRGGGG GGGGGGDGLL WHAELKPHAS GEYSIAVAQA NAELEDQGQV 70 80 90 100 110 120 VTSPAATFVG VYDGHGGPEA SRFISSRLFP HLHRFASEQG GMSTDAIKRA FHATEEEFLH 130 140 150 160 170 180 MVKRSWLKQP QIASVGSCCL VGAITDNVLY VANLGDSRAV LGRRGPDGRE VVAERLSNDH 190 200 210 220 230 240 NVAEEEVRKE LTEQHPDDSR IVIYTRGVWR IKGIIQVSRS IGDVYLKKPE FARDPIFRQY 250 260 270 280 290 300 VCSIPLKRPV MTAEPSIKEH QLRQQDLFLI FASDGLWEQL TDKAAVDIVF KNPRAGIAKR 310 320 330 340 350 360 LVRAALTEAA RKREMRYTDI KHIERGSRRN FHDDITVVVV YLDHHKHGVR PNLGNRNSFR 370 380 390 FTNAPVDIFS GSSEEVDHHP LRLNLAMDGA VG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." The rice chromosomes 11 and 12 sequencing consortia BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[5]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DP000011 Genomic DNA. Translation: ABA99127.1. AP008218 Genomic DNA. Translation: BAF30152.1. AK071206 mRNA. Translation: BAG92373.1.
RefSeq	NP_001067133.1. NM_001073665.1.
UniGene	Os.22969.
3D structure databases
ProteinModelPortal	Q2QN36.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os12g39120.1; LOC_Os12g39120.1; LOC_Os12g39120.
GeneID	4352638.
KEGG	osa:4352638.
Organism-specific databases
Gramene	Q2QN36.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000238703.
OMA	ETEEEFC.
ProtClustDB	CLSN2685703.
Gene expression databases
ArrayExpress	Q2QN36.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C78_ORYSJ

Accession

Primary (citable) accession number: Q2QN36

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	January 24, 2006
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program