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Reviewed, UniProtKB/Swiss-Prot Q2QMX9 (ACA1_ORYSJ)

Last modified June 16, 2009. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Calcium-transporting ATPase 1, plasma membrane-type
    EC=3.6.3.8
Alternative name(s):
    Ca(2+)-ATPase isoform 1
    Plastid envelope ATPase 1
Gene names
Ordered Locus Names: Os12g0586600, LOC_Os12g39660
OrganismOryza sativa subsp. japonica (Rice)
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

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Protein attributes

Sequence length1020 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles By similarity.

Catalytic activity

ATP + H2O + Ca2+(Cis) = ADP + phosphate + Ca2+(Trans).

Enzyme regulation

Activated by calmodulin By similarity.

Subcellular location

Membrane; Multi-pass membrane protein By similarity.

Domain

The N-terminus contains an autoinhibitory calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion By similarity.

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. Type IIB subfamily.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 10201020Calcium-transporting ATPase 1, plasma membrane-type
PRO_0000247300

Regions

Topological domain1 – 175175Cytoplasmic Potential
Transmembrane176 – 19621 Potential
Transmembrane199 – 21921 Potential
Topological domain220 – 26344Cytoplasmic Potential
Transmembrane264 – 28421 Potential
Transmembrane352 – 37221 Potential
Topological domain373 – 40028Cytoplasmic Potential
Transmembrane401 – 42121 Potential
Transmembrane843 – 86321 Potential
Topological domain864 – 88724Cytoplasmic Potential
Transmembrane888 – 90720 Potential
Transmembrane924 – 94421 Potential
Topological domain945 – 96117Cytoplasmic Potential
Transmembrane962 – 98221 Potential
Transmembrane995 – 101521 Potential
Topological domain1016 – 10205Cytoplasmic Potential
Region21 – 3212Interaction with calmodulin By similarity

Sites

Active site45614-aspartylphosphate intermediate By similarity
Metal binding7581Magnesium By similarity
Metal binding7621Magnesium By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q2QMX9-1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: B340D8999927D4F5

FASTA1,020111,151
        10         20         30         40         50         60 
MESYLEENFG GVKAKNSSEE ALRRWRKLCG VVKNPKRRFR FTANLDKRGE AQAIKHANHE 

        70         80         90        100        110        120 
KLRVAVLVSK AALQFIQGLS LRSEYVVPEE VKAAGFQICA DELGSIVEGH DSKKLITHGG 

       130        140        150        160        170        180 
VTGIADKLAT SPADGLSTAE ESIKRRQDVY GLNKFTESEV RSFWVFVWEA LQDTTLIILA 

       190        200        210        220        230        240 
VCAFVSLVVG IAMEGWPKGA HDGLGIVASI LLVVFVTATS DYRQSLQFKD LDKEKKKIQV 

       250        260        270        280        290        300 
QVTRNGFRQR LSIYDLLPGD VVHLAIGDQV PADGLFISGF SLLINESSLT GESEPVVVNE 

       310        320        330        340        350        360 
DNPFLLSGTK VQDGSCKMLI TTVGMRTQWG KLMATLSEGG DDETPLQVKL NGVATIIGKI 

       370        380        390        400        410        420 
GLFFAVITFI VLSQGLISKK YHEGLLLSWS GDDALEMLEH FAIAVTIVVV AVPEGLPLAV 

       430        440        450        460        470        480 
TLSLAFAMKK MMNDKALVRH LAACETMGSA TTICSDKTGT LTTNHMTVVK ACICGNIKEV 

       490        500        510        520        530        540 
NNPKNASDLC SELPETVVKT LLESIFNNTG GEVVIDQDGK YQILGTPTET ALLEFALSLG 

       550        560        570        580        590        600 
GNFKAKRDET KIVKMEPFNS TKKRMCVVLK LPGGGCRAHC KGASEIVLAA CDKFMDETGA 

       610        620        630        640        650        660 
VVPLDKTTAD KLNGIIESFA NEALRTLCLG YREMEEGFSV EEQIPLQGYT CIGIVGIKDP 

       670        680        690        700        710        720 
VRPGVRESVA TCRSAGIMVR MVTGDNINTA KAIARECGIL TEDGLAIEGP EFREKSLDEL 

       730        740        750        760        770        780 
LKLIPKIQVM ARSSPLDKHT LVKHLRTTFN EVVAVTGDGT NDAPALHEAD IGLAMGIAGT 

       790        800        810        820        830        840 
EVAKESADVI ILDDNFSTIV TVAKWGRSVY VNIQKFVQFQ LTVNVVALLV NFSSACFTGN 

       850        860        870        880        890        900 
APLTAVQLLW VNMIMDTLGA LALATEPPND DLMKREPVGR TGKFITNVMW RNILGQSFYQ 

       910        920        930        940        950        960 
FIVMWYLQTQ GKSMFGLDGP DAEVVLNTII FNSFVFCQVF NEISSREMEK INVLRGILKN 

       970        980        990       1000       1010       1020 
YVFLGVLTST VVFQFIMVQF LGEFANTIPL TRLQWIASVL LGLIGMPISA IIKLLPVGSS

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References

[1]"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
The rice chromosomes 11 and 12 sequencing consortia
BMC Biol. 3:20-20(2005) [PubMed: 16188032] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed: 12869764] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.

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Cross-references

Sequence databases

DP000011 Genomic DNA. Translation: ABA99736.1.
AK066259 mRNA. No translation available.
RefSeqNP_001067159.1.
UniGeneOs.55124

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID4352664.
KEGGosa:4352664.

Organism-specific databases

GrameneQ2QMX9.

Family and domain databases

InterProIPR008250. ATPase_P-typ_ATPase-assoc-reg.
IPR006408. ATPase_P-typ_Ca-transp_PMCA.
IPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR000695. ATPase_P-typ_H-transp.
IPR001757. ATPase_P-typ_ion-transptr.
IPR018303. ATPase_P-typ_phosphor_site.
IPR005834. Dehalogen-like_hydro.
[Graphical view]
PANTHERPTHR11939. ATPase_P. 1 hit.
PfamPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSPR00119. CATATPASE.
PR00120. HATPASE.
TIGRFAMsTIGR01517. ATPase-IIB_Ca. 1 hit.
TIGR01494. ATPase_P-type. 3 hits.
PROSITEPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameACA1_ORYSJ
AccessionPrimary (citable) accession number: Q2QMX9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: January 24, 2006
Last modified: June 16, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents