Reviewed, UniProtKB/Swiss-Prot Q2QM47 (BSL2_ORYSJ)

Names and origin

Protein names

Recommended name:
    Serine/threonine-protein phosphatase BSL2 homolog
    EC=3.1.3.16
Alternative name(s):
    BSU1-like protein 2 homolog

Gene names

Name:	BSL2
Ordered Locus Names:	Os12g0617900, LOC_Os12g42310

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	1009 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 1 iron ion per subunit By similarity. Binds 1 manganese ion per subunit By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the PPP phosphatase family. BSU subfamily. Contains 5 Kelch repeats.

Ontologies

Keywords
Cellular component	Nucleus
Domain	Kelch repeat Repeat
Ligand	Iron Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Gene Ontology (GO)
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoprotein phosphatase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1009	1009	Serine/threonine-protein phosphatase BSL2 homolog		PRO_0000247274
Regions
	Repeat	136 – 182	47	Kelch 1
	Repeat	240 – 288	49	Kelch 2
	Repeat	293 – 344	52	Kelch 3
	Repeat	349 – 396	48	Kelch 4
	Repeat	417 – 463	47	Kelch 5
	Compositional bias	21 – 28	8	Poly-Gly
	Compositional bias	44 – 83	40	Ala-rich
Sites
	Active site	778	1	Proton donor By similarity
	Metal binding	711	1	Iron By similarity
	Metal binding	713	1	Iron By similarity
	Metal binding	745	1	Iron By similarity
	Metal binding	745	1	Manganese By similarity
	Metal binding	777	1	Manganese By similarity
	Metal binding	830	1	Manganese By similarity
	Metal binding	909	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2QM47-1 [UniParc]. Last modified July 11, 2006. Version 2. Checksum: 9BDD845DC706A3A3	FASTA	1,009	106,426
	10 20 30 40 50 60 MDVDSRMTTE SDSDSDAAAQ GGGGGGFGSE TSSASPSAPG TPTAMGAGGG AAPIAAAAIA 70 80 90 100 110 120 AAASAAVVAG PRPAPGYTVV NAAMEKKEDG PGCRCGHTLT AVPAVGEEGA PGYVGPRLIL 130 140 150 160 170 180 FGGATALEGN SATPPSSAGS AGIRLAGATA DVHCYDVSSN KWSRLTPVGE PPSPRAAHVA 190 200 210 220 230 240 TAVGTMVVIQ GGIGPAGLSA EDLHVLDLTQ QRPRWHRVVV QGPGPGPRYG HVMALVGQRF 250 260 270 280 290 300 LLTIGGNDGK RPLADVWALD TAAKPYEWRK LEPEGEGPPP CMYATASARS DGLLLLCGGR 310 320 330 340 350 360 DANSVPLASA YGLAKHRDGR WEWAIAPGVS PSPRYQHAAV FVNARLHVSG GALGGGRMVE 370 380 390 400 410 420 DSSSVAVLDT AAGVWCDTKS VVTTPRTGRY SADAAGGDAS VELTRRCRHA AAAVGDMIYV 430 440 450 460 470 480 YGGLRGGVLL DDLLVAEDLA AAETTNAANQ AAAIAAASDI QAGREPGRYA YNDEQTGQPA 490 500 510 520 530 540 TITSPDGAVV LGTPVAAPVN GDMYTDISPE NAVIQGQRRM SKGVDYLVEA SAAEAEAISA 550 560 570 580 590 600 TLAAVKARQV NGEAEHSPDR EQSPDATPSV KQNASLIKPD YALSNNSTPP PGVRLHHRAV 610 620 630 640 650 660 VVAAETGGAL GGMVRQLSID QFENEGRRVI YGTPESATAA RKLLDRQMSI NSVPKKVIAS 670 680 690 700 710 720 LLKPRGWKPP VRRQFFLDCN EIADLCDSAE RIFSSEPSVL QLKAPIKIFG DLHGQFGDLM 730 740 750 760 770 780 RLFDEYGAPS TAGDIAYIDY LFLGDYVDRG QHSLETITLL LALKVEYPLN VHLIRGNHEA 790 800 810 820 830 840 ADINALFGFR IECIERMGER DGIWTWHRMN RLFNWLPLAA LIEKKIICMH GGIGRSINHV 850 860 870 880 890 900 EQIENLQRPI TMEAGSVVLM DLLWSDPTEN DSVEGLRPNA RGPGLVTFGP DRVMEFCNNN 910 920 930 940 950 960 DLQLIVRAHE CVMDGFERFA QGHLITLFSA TNYCGTANNA GAILVLGRDL VVVPKLIHPL 970 980 990 1000 PPAITSPETS PEHHLEDTWM QELNANRPPT PTRGRPQAAN NDRGSLAWI

References

[1]	"The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications." The rice chromosomes 11 and 12 sequencing consortia BMC Biol. 3:20-20(2005) [PubMed: 16188032] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DP000011 Genomic DNA. Translation: ABA99873.2. AK065064 mRNA. No translation available.
RefSeq	NP_001067290.1.
UniGene	Os.81458
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4352808.
KEGG	osa:4352808.
Family and domain databases
InterPro	IPR015915. Kelch-typ_b-propeller. IPR006652. Kelch_1. IPR011498. Kelch_2. IPR004843. M-pesterase. IPR012391. PPP_BSU1. IPR006186. T_phtase_apaH. [Graphical view]
Gene3D	G3DSA:2.120.10.80. Kelch-typ_b-propeller. 1 hit.
PANTHER	PTHR11668. T_phtase_apaH. 1 hit.
Pfam	PF01344. Kelch_1. 1 hit. PF07646. Kelch_2. 2 hits. PF00149. Metallophos. 1 hit. [Graphical view]
PIRSF	PIRSF036363. PPP_BSU1. 1 hit.
PRINTS	PR00114. STPHPHTASE.
ProDom	PD000252. T_phtase_apaH. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00156. PP2Ac. 1 hit. [Graphical view]
PROSITE	PS00125. SER_THR_PHOSPHATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BSL2_ORYSJ

Accession

Primary (citable) accession number: Q2QM47

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	July 11, 2006
Last modified:	June 16, 2009
This is version 32 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)