SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q2QBT8

- Q2QBT8_GIAIN

UniProt

Q2QBT8 - Q2QBT8_GIAIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: 14-3-3 protein
Gene
DHA2_6430, GSB_6430
Organism
Giardia intestinalis (Giardia lamblia)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei60 – 601Sulfate 2Imported
Binding sitei76 – 761Sulfate 3Imported
Binding sitei91 – 911Sulfate 6Imported
Binding sitei128 – 1281Sulfate 1Imported
Binding sitei128 – 1281Sulfate 7Imported
Binding sitei132 – 1321Sulfate 1Imported
Binding sitei180 – 1801Sulfate 1Imported
Binding sitei180 – 1801Sulfate 7Imported

Names & Taxonomyi

Protein namesi
Submitted name:
14-3-3 proteinImported
Submitted name:
Putative 14-3-3 domain proteinImported
Gene namesi
ORF Names:DHA2_6430Imported, GSB_6430Imported
OrganismiGiardia intestinalis (Giardia lamblia)Imported
Taxonomic identifieri5741 [NCBI]
Taxonomic lineageiEukaryotaDiplomonadidaHexamitidaeGiardiinaeGiardia
ProteomesiUP000018040: Unassembled WGS sequence, UP000018320: Unassembled WGS sequence

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F7RX-ray3.20A/B/C/D1-248[»]

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni76 – 783Sulfate 4 bindingImported
Regioni88 – 914Sulfate 5 bindingImported
Regioni135 – 1362Sulfate 2 bindingImported

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiIPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
[Graphical view]
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiPF00244. 14-3-3. 1 hit.
[Graphical view]
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiSM00101. 14_3_3. 1 hit.
[Graphical view]
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiPS00796. 1433_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2QBT8-1 [UniParc]FASTAAdd to Basket

« Hide

MAEAFTREDY VFMAQLNENA ERYDEMVETM RKISGMEGEL SDKERNLLSV    50
AYKNVIGPRR AAWRIVSSIE AKEKGRQKPN AKRIEQIRVY RQKIEKELSD 100
ICNDILKLLQ EQFVPRSTNA DAKVFYYKMQ GDYYRYLAEY SSGEDKEKIA 150
GSALNAYNSA FEISQQLPPT HPIRLGLALN FSVFYYEILA SPDRACELAR 200
KAFDAAITDL DKLTEESYKD STLIMQLLRD NLNLWVTDSA GDDNAEEK 248
Length:248
Mass (Da):28,576
Last modified:January 24, 2006 - v1
Checksum:i83E4D80EDED75B14
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ146480 Genomic DNA. Translation: AAZ91664.1.
AHGT01000002 Genomic DNA. Translation: ESU39602.1.
AHHH01000057 Genomic DNA. Translation: ESU43177.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ146480 Genomic DNA. Translation: AAZ91664.1 .
AHGT01000002 Genomic DNA. Translation: ESU39602.1 .
AHHH01000057 Genomic DNA. Translation: ESU43177.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4F7R X-ray 3.20 A/B/C/D 1-248 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.20.190.20. 1 hit.
InterProi IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
[Graphical view ]
PANTHERi PTHR18860. PTHR18860. 1 hit.
Pfami PF00244. 14-3-3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000868. 14-3-3. 1 hit.
PRINTSi PR00305. 1433ZETA.
SMARTi SM00101. 14_3_3. 1 hit.
[Graphical view ]
SUPFAMi SSF48445. SSF48445. 1 hit.
PROSITEi PS00796. 1433_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Giardia duodenalis 14-3-3 protein is post-translationally modified by phosphorylation and polyglycylation of the C-terminal tail."
    Lalle M., Salzano A.M., Crescenzi M., Pozio E.
    J. Biol. Chem. 281:5137-5148(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WB-C6Imported.
  2. "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and Pig)."
    Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F., Nash T.
    Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: DHImported and GSImported.
  3. "The crystal structure of Giardia duodenalis 14-3-3 in the apo form: when protein post-translational modifications make the difference."
    Fiorillo A., di Marino D., Bertuccini L., Via A., Pozio E., Camerini S., Ilari A., Lalle M.
    PLoS ONE 9:e92902-e92902(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS).

Entry informationi

Entry nameiQ2QBT8_GIAIN
AccessioniPrimary (citable) accession number: Q2QBT8
Secondary accession number(s): A8BJ73, C6LVW8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: September 3, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

Similar proteinsi