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Protein
Submitted name:

Tumor necrosis factor (Ligand) superfamily member 13 transcript variant delta

Gene

TNFSF13

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factor (Ligand) superfamily member 13 transcript variant deltaImported
Submitted name:
Tumor necrosis factor ligand superfamily member 13Imported
Gene namesi
Name:TNFSF13Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000161955.16.
HGNCiHGNC:11928. TNFSF13.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 50HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000161955.

Expressioni

Gene expression databases

BgeeiENSG00000161955.
ExpressionAtlasiQ2QBA2. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ2QBA2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 223TNF_2InterPro annotationAdd BLAST134

Sequence similaritiesi

Belongs to the tumor necrosis factor family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410II60. Eukaryota.
ENOG410Y4KC. LUCA.
GeneTreeiENSGT00530000063837.
HOGENOMiHOG000036810.
HOVERGENiHBG104367.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiView protein in InterPro
IPR021184. TNF_CS.
IPR006052. TNF_dom.
IPR008983. Tumour_necrosis_fac-like_dom.
PfamiView protein in Pfam
PF00229. TNF. 1 hit.
SMARTiView protein in SMART
SM00207. TNF. 1 hit.
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiView protein in PROSITE
PS00251. TNF_1. 1 hit.
PS50049. TNF_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2QBA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT
60 70 80 90 100
QQTELQSLRR EVSRLQGTGG PSQNGEGYPW QSLPEQQHSV LHLVPINATS
110 120 130 140 150
KDDSDVTEVM WQPALRRGRG LQAQGYGVRI QDAGVYLLYS QVLFQDVTFT
160 170 180 190 200
MGQVVSREGQ GRQETLFRCI RSMPSHPDRA YNSCYSAGVF HLHQGDILSV
210 220
IIPRARAKLN LSPHGTFLGF VKL
Length:223
Mass (Da):24,279
Last modified:January 24, 2006 - v1
Checksum:i341F54179B86F2C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC016876 Genomic DNA. No translation available.
DQ149579 mRNA. Translation: ABA39072.1.
RefSeqiNP_001185551.1. NM_001198622.1.
UniGeneiHs.54673.

Genome annotation databases

EnsembliENST00000380535; ENSP00000369908; ENSG00000161955.
GeneIDi8741.
UCSCiuc010cmk.2. human.

Similar proteinsi

Entry informationi

Entry nameiQ2QBA2_HUMAN
AccessioniPrimary (citable) accession number: Q2QBA2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 24, 2006
Last sequence update: January 24, 2006
Last modified: September 27, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported