DNA methyltransferase - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q2PJS8 (Q2PJS8_HUMAN)

Last modified March 3, 2009. Version 18. History...

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
DNA methyltransferase EMBL ABC48951.1

Gene names

Name:

DNMT3B EMBL ABC48951.1

Organism

Homo sapiens (Human) EMBL ABC48951.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Methyltransferase Transferase
Gene Ontology (GO)
Biological process	DNA methylation Inferred from electronic annotation. Source: Compara genetic imprinting Inferred from electronic annotation. Source: Compara methylation-dependent chromatin silencing Inferred from electronic annotation. Source: Compara protein complex localization Inferred from electronic annotation. Source: Compara
Cellular component	nuclear heterochromatin Inferred from electronic annotation. Source: Compara
Molecular function	DNA (cytosine-5-)-methyltransferase activity Inferred from electronic annotation. Source: Compara protein binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q2PJS8-1 [UniParc].

Last modified January 24, 2006. Version 1.
Checksum: F97EAA04FBBEA0C3
Show »

360

39,451

        10         20         30         40         50         60 
MKGDTRHLNG EEDAGGREDS ILVNGACSDQ SSDSPPILEA IRTPEIRGRR SSSRLSKREV 

        70         80         90        100        110        120 
SSLLSYTQDL TGDGDGEDGD GSDTPVMPKL FRETRTRSES PAVRTRNNNS VSSRERHRPS 

       130        140        150        160        170        180 
PRSTRGRQGR NHVDESPVEF PATRSLRRRA TASAGTPWPS PPSSYLTIDL TDDTEDTHGT 

       190        200        210        220        230        240 
PQSSSTPYAR LAQDSQQGGM ESPQVEADSG DGDSSEYQDG KEFGIGDLVW GKIKGFSWWP 

       250        260        270        280        290        300 
AMVVSWKATS KRQAMSGMRW VQWFGDGKFS EVSADKLVAL GLFSQHFNLA TFNKLVSYRK 

       310        320        330        340        350        360 
AMYHALEKAR VRAGKTFPSS PGDSLEDQLK PMLEWAHGGF KPTGIEGLKP NNTQPAGTQA

References

[1]	"Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins." Ostler K.R., Davis E.M., Payne S.L., Gosalia B.B., Exposito-Cespedes J., Le Beau M.M., Godley L.A. Oncogene 26:5553-5563(2007) [PubMed: 17353906] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
	DQ321787 mRNA. Translation: ABC48951.1.
IPI	IPI00782955.
UniGene	Hs.713611
3D structure databases
SMR	Q2PJS8. Positions 216-350.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000088305. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:2979. DNMT3B.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q2PJS8.
Gene expression databases
ArrayExpress	Q2PJS8.
Bgee	Q2PJS8.
Family and domain databases
InterPro	IPR000313. PWWP. [Graphical view]
Pfam	PF00855. PWWP. 1 hit. [Graphical view]
SMART	SM00293. PWWP. 1 hit. [Graphical view]
PROSITE	PS50812. PWWP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2PJS8_HUMAN

Accession

Primary (citable) accession number: Q2PJS8

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	March 3, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information