Unreviewed, UniProtKB/TrEMBL Q2PJS8 (Q2PJS8_HUMAN)

Names and origin

Protein names

Submitted name:
    DNA methyltransferase EMBL ABC48951.1

Gene names

Name:

DNMT3B EMBL ABC48951.1

Organism

Homo sapiens (Human) EMBL ABC48951.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Methyltransferase Transferase
Gene Ontology (GO)
Molecular function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2PJS8-1 [UniParc]. Last modified January 24, 2006. Version 1. Checksum: F97EAA04FBBEA0C3	FASTA	360	39,451
	10 20 30 40 50 60 MKGDTRHLNG EEDAGGREDS ILVNGACSDQ SSDSPPILEA IRTPEIRGRR SSSRLSKREV 70 80 90 100 110 120 SSLLSYTQDL TGDGDGEDGD GSDTPVMPKL FRETRTRSES PAVRTRNNNS VSSRERHRPS 130 140 150 160 170 180 PRSTRGRQGR NHVDESPVEF PATRSLRRRA TASAGTPWPS PPSSYLTIDL TDDTEDTHGT 190 200 210 220 230 240 PQSSSTPYAR LAQDSQQGGM ESPQVEADSG DGDSSEYQDG KEFGIGDLVW GKIKGFSWWP 250 260 270 280 290 300 AMVVSWKATS KRQAMSGMRW VQWFGDGKFS EVSADKLVAL GLFSQHFNLA TFNKLVSYRK 310 320 330 340 350 360 AMYHALEKAR VRAGKTFPSS PGDSLEDQLK PMLEWAHGGF KPTGIEGLKP NNTQPAGTQA

References

[1]	"Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins." Ostler K.R., Davis E.M., Payne S.L., Gosalia B.B., Exposito-Cespedes J., Le Beau M.M., Godley L.A. Oncogene 26:5553-5563(2007) [PubMed: 17353906] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ321787 mRNA. Translation: ABC48951.1.
UniGene	Hs.643024 Hs.655708
3D structure databases
SMR	Q2PJS8. Positions 216-350.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000088305. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:2979. DNMT3B.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q2PJS8.
Gene expression databases
ArrayExpress	Q2PJS8.
Family and domain databases
InterPro	IPR000313. PWWP. [Graphical view]
Pfam	PF00855. PWWP. 1 hit. [Graphical view]
SMART	SM00293. PWWP. 1 hit. [Graphical view]
PROSITE	PS50812. PWWP. 1 hit. [Graphical view]

Entry information

Entry name

Q2PJS8_HUMAN

Accession

Primary (citable) accession number: Q2PJS8

Entry history

Integrated into UniProtKB/TrEMBL:	January 24, 2006
Last sequence update:	January 24, 2006
Last modified:	July 22, 2008
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)