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Q2PC93

- SSPO_CHICK

UniProt

Q2PC93 - SSPO_CHICK

Protein

SCO-spondin

Gene

SSPO

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system By similarity.By similarity

    GO - Biological processi

    1. cell adhesion Source: UniProtKB-KW

    Keywords - Biological processi

    Cell adhesion

    Keywords - Ligandi

    Calcium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SCO-spondin
    Gene namesi
    Name:SSPO
    OrganismiGallus gallus (Chicken)
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Unplaced

    Subcellular locationi

    Secretedextracellular space By similarity

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 52555237SCO-spondinPRO_0000245045Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi? ↔ 5247By similarity
    Glycosylationi97 – 971N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi136 – 1361N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi156 – 1561N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi255 – 2551N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi801 – 8011N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi931 – 9311N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi972 – 9721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1340 – 13401N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1363 ↔ 1376By similarity
    Disulfide bondi1370 ↔ 1389By similarity
    Disulfide bondi1383 ↔ 1397By similarity
    Disulfide bondi1401 ↔ 1413By similarity
    Disulfide bondi1408 ↔ 1426By similarity
    Disulfide bondi1420 ↔ 1435By similarity
    Disulfide bondi1440 ↔ 1452By similarity
    Disulfide bondi1447 ↔ 1465By similarity
    Disulfide bondi1459 ↔ 1476By similarity
    Disulfide bondi1480 ↔ 1492By similarity
    Disulfide bondi1487 ↔ 1505By similarity
    Disulfide bondi1499 ↔ 1514By similarity
    Disulfide bondi1516 ↔ 1528By similarity
    Disulfide bondi1523 ↔ 1541By similarity
    Disulfide bondi1535 ↔ 1550By similarity
    Disulfide bondi1556 ↔ 1568By similarity
    Disulfide bondi1563 ↔ 1581By similarity
    Disulfide bondi1575 ↔ 1592By similarity
    Glycosylationi1610 – 16101N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1617 ↔ 1629By similarity
    Disulfide bondi1624 ↔ 1642By similarity
    Disulfide bondi1636 ↔ 1651By similarity
    Glycosylationi1652 – 16521N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1655 ↔ 1668By similarity
    Disulfide bondi1662 ↔ 1681By similarity
    Disulfide bondi1675 ↔ 1692By similarity
    Disulfide bondi1700 ↔ 1711By similarity
    Disulfide bondi1706 ↔ 1724By similarity
    Glycosylationi1713 – 17131N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1718 ↔ 1733By similarity
    Glycosylationi1743 – 17431N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1749 ↔ 1759By similarity
    Disulfide bondi1754 ↔ 1772By similarity
    Disulfide bondi1766 ↔ 1789By similarity
    Disulfide bondi1801 ↔ 1837By similarity
    Disulfide bondi1805 ↔ 1842By similarity
    Disulfide bondi1816 ↔ 1827By similarity
    Glycosylationi1856 – 18561N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1857 ↔ 1897By similarity
    Disulfide bondi1861 ↔ 1902By similarity
    Disulfide bondi1871 ↔ 1881By similarity
    Disulfide bondi2003 ↔ 2042By similarity
    Disulfide bondi2014 ↔ 2018By similarity
    Disulfide bondi2052 ↔ 2057By similarity
    Glycosylationi2125 – 21251N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi2162 ↔ 2310By similarity
    Glycosylationi2230 – 22301N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi2328 ↔ 2339By similarity
    Disulfide bondi2335 ↔ 2352By similarity
    Disulfide bondi2346 ↔ 2361By similarity
    Disulfide bondi2482 ↔ 2494By similarity
    Disulfide bondi2489 ↔ 2507By similarity
    Disulfide bondi2501 ↔ 2516By similarity
    Disulfide bondi2539 ↔ 2551By similarity
    Disulfide bondi2546 ↔ 2564By similarity
    Disulfide bondi2558 ↔ 2573By similarity
    Disulfide bondi2576 ↔ 2612By similarity
    Disulfide bondi2587 ↔ 2591By similarity
    Disulfide bondi2622 ↔ 2627By similarity
    Disulfide bondi2642 ↔ 2679By similarity
    Disulfide bondi2646 ↔ 2684By similarity
    Disulfide bondi2657 ↔ 2669By similarity
    Glycosylationi2746 – 27461N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi2791 ↔ 2829By similarity
    Disulfide bondi2802 ↔ 2806By similarity
    Disulfide bondi2839 ↔ 2843By similarity
    Disulfide bondi2861 ↔ 2897By similarity
    Disulfide bondi2865 ↔ 2902By similarity
    Disulfide bondi2881 ↔ 2887By similarity
    Disulfide bondi2917 ↔ 2952By similarity
    Disulfide bondi2921 ↔ 2957By similarity
    Disulfide bondi2932 ↔ 2942By similarity
    Glycosylationi3011 – 30111N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3042 – 30421N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi3061 ↔ 3099By similarity
    Glycosylationi3065 – 30651N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi3072 ↔ 3076By similarity
    Disulfide bondi3109 ↔ 3114By similarity
    Glycosylationi3136 – 31361N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3238 – 32381N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3248 – 32481N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi3270 ↔ 3303By similarity
    Disulfide bondi3274 ↔ 3308By similarity
    Disulfide bondi3285 ↔ 3293By similarity
    Glycosylationi3350 – 33501N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3366 – 33661N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3392 – 33921N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi3422 ↔ 3468By similarity
    Disulfide bondi3426 ↔ 3474By similarity
    Disulfide bondi3437 ↔ 3449By similarity
    Disulfide bondi3489 ↔ 3524By similarity
    Disulfide bondi3492 ↔ 3531By similarity
    Disulfide bondi3502 ↔ 3514By similarity
    Glycosylationi3598 – 35981N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3625 – 36251N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi3656 ↔ 3693By similarity
    Disulfide bondi3660 ↔ 3699By similarity
    Disulfide bondi3671 ↔ 3683By similarity
    Disulfide bondi3714 ↔ 3745By similarity
    Disulfide bondi3718 ↔ 3750By similarity
    Disulfide bondi3729 ↔ 3735By similarity
    Glycosylationi3823 – 38231N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi3869 – 38691N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi3890 ↔ 3928By similarity
    Disulfide bondi3894 ↔ 3933By similarity
    Disulfide bondi3906 ↔ 3918By similarity
    Disulfide bondi3963 ↔ 3998By similarity
    Disulfide bondi3967 ↔ 4003By similarity
    Disulfide bondi3982 ↔ 3988By similarity
    Glycosylationi4018 – 40181N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi4019 ↔ 4055By similarity
    Disulfide bondi4030 ↔ 4034By similarity
    Disulfide bondi4068 ↔ 4073By similarity
    Disulfide bondi4088 ↔ 4125By similarity
    Disulfide bondi4092 ↔ 4130By similarity
    Disulfide bondi4103 ↔ 4115By similarity
    Glycosylationi4174 – 41741N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi4211 – 42111N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi4231 ↔ 4266By similarity
    Disulfide bondi4242 ↔ 4246By similarity
    Disulfide bondi4276 ↔ 4281By similarity
    Glycosylationi4362 – 43621N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi4387 ↔ 4417By similarity
    Disulfide bondi4398 ↔ 4400By similarity
    Disulfide bondi4427 ↔ 4432By similarity
    Glycosylationi4428 – 44281N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi4498 – 44981N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi4548 ↔ 4601By similarity
    Disulfide bondi4551 ↔ 4607By similarity
    Disulfide bondi4575 ↔ 4591By similarity
    Disulfide bondi4611 ↔ 4646By similarity
    Disulfide bondi4622 ↔ 4626By similarity
    Disulfide bondi4656 ↔ 4661By similarity
    Glycosylationi4730 – 47301N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi4747 – 47471N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi4752 – 47521N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi4774 ↔ 4809By similarity
    Disulfide bondi4778 ↔ 4814By similarity
    Disulfide bondi4789 ↔ 4798By similarity
    Disulfide bondi4818 ↔ 4852By similarity
    Disulfide bondi4829 ↔ 4833By similarity
    Disulfide bondi4863 ↔ 4868By similarity
    Glycosylationi4867 – 48671N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi4939 – 49391N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi4970 – 49701N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi4980 ↔ 5017By similarity
    Disulfide bondi4991 ↔ 4995By similarity
    Disulfide bondi5027 ↔ 5032By similarity
    Glycosylationi5081 – 50811N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi5122 – 51221N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi5161 ↔ 5209By similarity
    Glycosylationi5169 – 51691N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi5175 ↔ 5226By similarity
    Disulfide bondi5185 ↔ 5242By similarity
    Disulfide bondi5189 ↔ 5244By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ2PC93.

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000038585.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2PC93.
    SMRiQ2PC93. Positions 3059-3085.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini19 – 11193EMIAdd
    BLAST
    Domaini193 – 395203VWFD 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini453 – 50856TIL 1Add
    BLAST
    Domaini508 – 60194VWFC 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini547 – 755209VWFD 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini809 – 86860TIL 2Add
    BLAST
    Domaini868 – 92659VWFC 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini999 – 1207209VWFD 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini1263 – 131957TIL 3Add
    BLAST
    Domaini1362 – 139837LDL-receptor class A 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini1400 – 143637LDL-receptor class A 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini1439 – 147739LDL-receptor class A 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini1479 – 151537LDL-receptor class A 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini1515 – 155137LDL-receptor class A 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini1555 – 159339LDL-receptor class A 6PROSITE-ProRule annotationAdd
    BLAST
    Domaini1616 – 165237LDL-receptor class A 7PROSITE-ProRule annotationAdd
    BLAST
    Domaini1654 – 169340LDL-receptor class A 8PROSITE-ProRule annotationAdd
    BLAST
    Domaini1699 – 173436LDL-receptor class A 9PROSITE-ProRule annotationAdd
    BLAST
    Domaini1748 – 179043LDL-receptor class A 10PROSITE-ProRule annotationAdd
    BLAST
    Domaini1789 – 184355TSP type-1 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini1845 – 190359TSP type-1 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini1907 – 196155TIL 4Add
    BLAST
    Domaini1919 – 195638EGF-like 1Add
    BLAST
    Domaini1957 – 198327EGF-like 2Add
    BLAST
    Domaini1961 – 201959VWFC 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini2002 – 205857TSP type-1 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini2058 – 212063VWFC 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini2162 – 2310149F5/8 type CPROSITE-ProRule annotationAdd
    BLAST
    Domaini2327 – 236236LDL-receptor class A 11PROSITE-ProRule annotationAdd
    BLAST
    Domaini2481 – 251737LDL-receptor class A 12PROSITE-ProRule annotationAdd
    BLAST
    Domaini2538 – 257437LDL-receptor class A 13PROSITE-ProRule annotationAdd
    BLAST
    Domaini2575 – 262854TSP type-1 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini2630 – 268556TSP type-1 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini2708 – 275043TIL 5Add
    BLAST
    Domaini2790 – 284455TSP type-1 6PROSITE-ProRule annotationAdd
    BLAST
    Domaini2849 – 290355TSP type-1 7PROSITE-ProRule annotationAdd
    BLAST
    Domaini2905 – 295854TSP type-1 8PROSITE-ProRule annotationAdd
    BLAST
    Domaini3020 – 307758VWFC 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini3060 – 311556TSP type-1 9PROSITE-ProRule annotationAdd
    BLAST
    Domaini3117 – 315842TSP type-1 10PROSITE-ProRule annotationAdd
    BLAST
    Domaini3165 – 321753TIL 6Add
    BLAST
    Domaini3217 – 327559VWFC 6PROSITE-ProRule annotationAdd
    BLAST
    Domaini3258 – 330952TSP type-1 11PROSITE-ProRule annotationAdd
    BLAST
    Domaini3410 – 347566TSP type-1 12PROSITE-ProRule annotationAdd
    BLAST
    Domaini3477 – 353256TSP type-1 13PROSITE-ProRule annotationAdd
    BLAST
    Domaini3644 – 370057TSP type-1 14PROSITE-ProRule annotationAdd
    BLAST
    Domaini3702 – 375150TSP type-1 15PROSITE-ProRule annotationAdd
    BLAST
    Domaini3878 – 393457TSP type-1 16PROSITE-ProRule annotationAdd
    BLAST
    Domaini3951 – 400454TSP type-1 17PROSITE-ProRule annotationAdd
    BLAST
    Domaini4018 – 407457TSP type-1 18PROSITE-ProRule annotationAdd
    BLAST
    Domaini4076 – 413156TSP type-1 19PROSITE-ProRule annotationAdd
    BLAST
    Domaini4230 – 428253TSP type-1 20PROSITE-ProRule annotationAdd
    BLAST
    Domaini4322 – 438463TSP type-1 21PROSITE-ProRule annotationAdd
    BLAST
    Domaini4386 – 443348TSP type-1 22PROSITE-ProRule annotationAdd
    BLAST
    Domaini4537 – 460872TSP type-1 23PROSITE-ProRule annotationAdd
    BLAST
    Domaini4610 – 466253TSP type-1 24PROSITE-ProRule annotationAdd
    BLAST
    Domaini4762 – 481554TSP type-1 25PROSITE-ProRule annotationAdd
    BLAST
    Domaini4817 – 486953TSP type-1 26PROSITE-ProRule annotationAdd
    BLAST
    Domaini4872 – 492655TIL 7Add
    BLAST
    Domaini4979 – 503355TSP type-1 27PROSITE-ProRule annotationAdd
    BLAST
    Domaini5092 – 515059VWFC 7PROSITE-ProRule annotationAdd
    BLAST
    Domaini5161 – 524888CTCKPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi737 – 7426Poly-Ala

    Sequence similaritiesi

    Belongs to the thrombospondin family.Curated
    Contains 1 CTCK (C-terminal cystine knot-like) domain.PROSITE-ProRule annotation
    Contains 2 EGF-like domains.Curated
    Contains 1 EMI domain.Curated
    Contains 1 F5/8 type C domain.PROSITE-ProRule annotation
    Contains 13 LDL-receptor class A domains.PROSITE-ProRule annotation
    Contains 27 TSP type-1 domains.PROSITE-ProRule annotation
    Contains 7 VWFC domains.PROSITE-ProRule annotation
    Contains 3 VWFD domains.PROSITE-ProRule annotation

    Keywords - Domaini

    EGF-like domain, Repeat, Signal

    Phylogenomic databases

    eggNOGiNOG12793.
    HOVERGENiHBG080794.
    PhylomeDBiQ2PC93.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    4.10.400.10. 13 hits.
    InterProiIPR000421. Coagulation_fac_5/8-C_type_dom.
    IPR006207. Cys_knot_C.
    IPR008979. Galactose-bd-like.
    IPR023415. LDLR_class-A_CS.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR000884. Thrombospondin_1_rpt.
    IPR002919. TIL_dom.
    IPR014853. Unchr_dom_Cys-rich.
    IPR001007. VWF_C.
    IPR001846. VWF_type-D.
    [Graphical view]
    PfamiPF08742. C8. 3 hits.
    PF00754. F5_F8_type_C. 1 hit.
    PF00057. Ldl_recept_a. 11 hits.
    PF01826. TIL. 13 hits.
    PF00090. TSP_1. 25 hits.
    PF00093. VWC. 1 hit.
    PF00094. VWD. 3 hits.
    [Graphical view]
    PRINTSiPR00261. LDLRECEPTOR.
    SMARTiSM00832. C8. 3 hits.
    SM00231. FA58C. 1 hit.
    SM00192. LDLa. 13 hits.
    SM00209. TSP1. 27 hits.
    SM00214. VWC. 5 hits.
    SM00216. VWD. 3 hits.
    [Graphical view]
    SUPFAMiSSF49785. SSF49785. 1 hit.
    SSF57424. SSF57424. 12 hits.
    SSF57567. SSF57567. 15 hits.
    SSF82895. SSF82895. 25 hits.
    PROSITEiPS01225. CTCK_2. 1 hit.
    PS01285. FA58C_1. 1 hit.
    PS01286. FA58C_2. 1 hit.
    PS50022. FA58C_3. 1 hit.
    PS01209. LDLRA_1. 11 hits.
    PS50068. LDLRA_2. 13 hits.
    PS50092. TSP1. 27 hits.
    PS01208. VWFC_1. 1 hit.
    PS50184. VWFC_2. 2 hits.
    PS51233. VWFD. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q2PC93-1 [UniParc]FASTAAdd to Basket

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    MGIVATVLLW VVTEAARGRW CERTEQVTEE EVVMPRREDV VPCPSMYQYS     50
    LAGWRIDLNR MRQVYGGERG VPPTSTHPGA AMCYIYRPPE TQLVVRNRTV 100
    RACCAGWSGP HCTEVEGSLG QCHASWQCQD ALGAHNLSTV SMAECCRQPW 150
    GHSWRNGSSA LCFACSRQPL TGDVPLPTAP RGPAARHRGP TASCTVWAGS 200
    RYRSFDGRHF GFQGECAYSL AASTDSTWAV SITPGSPPVL HMTFGLDTVV 250
    AQGHNISVNG VAVPEGRQHL HGGISVTWLG DFVAVESGLG VHLKLDGRGT 300
    VYVTVSAELR GSTKGLCGPY NDDPIDDFLR VEGDVAPLAA SFGNSWRIPD 350
    ANPELSCSDA VEPSPGCAMG STAQRAAEAM CGMLLTDPFR QCHEAVDPHG 400
    FYEACLELHC REGGTGPSPP PAVCDTLATY VRDCAQRRAY IEWRRPGLCE 450
    QQCGHGQRYS DCVSSCPASC MAAGTAEEGH CRDDCASGCE CTPGLLLDRG 500
    ACIPQSACPC LHRGHIYAPG QSIRQRCNQC TCRGGRWLCT QDRCAAECAV 550
    LGDLHYITFD RRRFSFPGAC EYTLVQDFVE GTLRITAEQE ACGGHQPLSC 600
    LRALSITVPG ASARLHSTGE VVVDGRVVPL PFASAALTVR RASSSFLLLQ 650
    TFGAHLLWGL ETPAAYITLQ PAFANKVRGL CGTYNWDQRD DFATPAGDVE 700
    VGVTAFANKY RVSTDCPVLS PVPFEPCSTY APRRELAAAA CAILHGASFQ 750
    PCHHLVDREP FHQLCLYDVC ACPAGKHCLC PALAAYAREC AQEGAALSWR 800
    NESFCGTQCR GGQVYQECSS PCGRTCADLR LDGASSCPSL DNICVSGCNC 850
    PEGPVLDDGG QCVPPGVCPC QHSSQLYPAG SKIRQGCNAC MCTAGTWSCT 900
    DAPCPDAAFC PGDLVYVFGS CLRTCDSAEP NGTCTGIADG CVCPPGTVFL 950
    DERCVPPEEC PCQHNGRLYH PNDTIVRDCN TCVCRQQRWQ CSSEDCMGTC 1000
    VATGDPHYIT FDGRAFSFLG DCEYVLVREA NGLFTVTAEN VPCGTSGVTC 1050
    TKSVVVEMGN TVVHMLRGRD VTVNGVSVRP PKVYSGNGLT LQRAGIFLLL 1100
    LSRLGLAVLW DGGTRVYIRL QPQHRGRVVG LCGNFDRDAE NDLASQQGVL 1150
    EPTAELFGNS WRVSLLCPEV DGTTAQHPCT DNPHRATWAR KRCSILTQRL 1200
    FAPCHDEVPC QHFYDWCIFD ACGCDSGGDC ECLCTAIATY AEECSQRGIH 1250
    IRWRSQDLCP MQCDGGQEYS ACGPPCPQTC RNLGLELPEH CDTMSCLEGC 1300
    FCPEGKVLHE GSCIDPAECP CFWQGIAFPD SAVVQQGCRN CSCTAGLWQC 1350
    VPTAEPCPAQ PHCPDSEFPC RSGGRCVPGA WLCDNEDDCG DGSDEVCALH 1400
    CAPHQHRCAD GQCVPWGARC DGLSDCGDGS DERGCPPPPC APPEFRCASG 1450
    RCIPRAHVCN GELDCGFADD SDEAGCSPSC SVGEFQCAAG RCVPYPHRCN 1500
    GHDDCGDFSD ERGCVCPAGH FQCPDAQCLP PAALCDGMQD CGDGTDEAFC 1550
    PDRITCAPGQ LPCPDGSCVS QVKLCDGIWD CRDGWDESSV RCMVSWAPPA 1600
    PTQLPTVPAN GTAAPVCGPY EFPCRSGQCV PRGWVCDSEA DCPDNSDELG 1650
    CNRSCVLGHF PCALGAHCIH YDHLCDGIPH CPDHSDESDD NCGSTQIPPC 1700
    PGHFVCNNRV CVNATRVCDG ALDCPQGEDE LACEGYVPTG ERNQTVGPCA 1750
    EYSCRDGDCI TFKQVCNGLP DCRDGDMASG WLPSDEWDCG QWGPWAPWGI 1800
    CSHSCGLGQQ LRARECSQRT PGVLHQCHGE ATQARPCFST ACPVDGAWSE 1850
    WTMWSNCTQG CEGVVVRQRH CQPPRDGGRP CAALPATAHA TLEIGTCQQD 1900
    GCPPASCPGG LQPRPCAPCP ASCADLASRA PCRREQCTPG CWCAEGLVLD 1950
    GERGCVRPRE CRCEVDGLRY WPGQRMKLNC RLCTCLDGQP RRCRHNPACS 2000
    VSCSWSAWSP WGECLGPCGV QSIQWSFRSP SHPGKHGTNR QCRGIYRKAR 2050
    RCQTEPCQEC EHQGRSRAQG DRWRWGPCHV CQCLPGPEVR CSPYCARSAV 2100
    GCPQGQVLVE GKGDSCCFCA QIGDNVTAIP TALTMEPPST MPGEPSDSPL 2150
    PTFPLPSPGD PCYSPLGIAS LPDSSFTASA EQQQHPARAA RLHHVSPGLE 2200
    LQGWAPPADT VPGLPSHLPF LQLDLLQTTN LTGVVVQGAG AGDAFITAFQ 2250
    LQFSTDGNRW HNYQQLFQGN WDATTPVVQP LDHMVQARYI RILPQGFHNA 2300
    IFLRAELLGC PTVPLDLAVT TAVTPAPCGT GEFWCGVSCV TASRRCDGAT 2350
    DCPGGADEAG CEPPSSTTLP THPASLTTPG SAGILGLTAE PPVAPPAAVP 2400
    EGTSAWLTVG STSPAVPSTT GLPGVPTATI TPRGPPSAGP PSPGMAAVTV 2450
    SHPVMGPPAL PMPPTGVPTP TSAEPPLPRL LCPPDQFLCD ALGCVDAAMV 2500
    CDGQQDCLDG SDEAHCGALP TSGSSPSPLA WPSSPPPTCS PKQFSCGTGE 2550
    CLALEKRCDL SRDCADGSDE SSCADCILSP WGGWSQCSHS CGLGVTSRQR 2600
    VLLRGALPGG TCHTPRLDTR ACFLRACPVP GAWAAWGVWS SCDAECGGGM 2650
    RSRTRSCTDP PPKNGGQPCA GEALQSQPCN LQPCGDTREC GPGMVLVQEG 2700
    DCVQGLVPPC PQVCGDLSAT SSCQSPCQEG CRCPPGLFLQ EGTCVNASQC 2750
    HCHQGQQRWL PSQVFLRDGC SQCVCRDGVV TCEDTACPIA CAWSAWSLWT 2800
    LCDRSCGVGM QERFRSPSNP AAANGGAPCD GDTREVRECH TPCATAEPSS 2850
    GWSSWTPWSP CSRSCFHHVD QRGRRHRFRH CEGMGTCPGL GVQEEPCDTA 2900
    PCPVAGVWMP WSAWSECSAP CDAGVQTRSR TCTPPAFGGA ECTGPHLQTR 2950
    NCNTRPCGAQ CPDTMQYLTA EECRHSEGRC PWICQDLGAG VACTAQCQPG 3000
    CHCPAGLLLQ NGTCVPPSHC LCHHRGHLYQ PGDINALDTC NNCTCVTGQM 3050
    VCSTETCPVP CTWSNWTAWS TCSHSCDVGM RRRYRVPIVP PLAGGGPPCQ 3100
    GPSMEVEFCS LQPCRAVAPW GPWSECSVSC GGGYRNRTRD GPPLHSLEFS 3150
    TCNPAPCPGK EPGVCPPGKQ WQACAQGAAS CAELSAAPPA DGSCHPGCYC 3200
    PPGALLLNNE CVAEAACPCA VDGVLYQPGD VVPQGCHNCS CIAGRVTNCS 3250
    QEDCGDVDGP WTPWTPWSEC SASCGPGRQR RYRFCSAHPG VPCAEPQPQE 3300
    RPCARQPCHS PDCAAVPGSV FSHCRPPCPR SCDDISHCVW HRQPGCYCTN 3350
    GTLLDATGTA CVALENCTCL DAHSGQRHQP GQSVPRGDGC NNCTCTQGRL 3400
    LCTGLPCPVP GAWCEWSPWT PCSRSCGDEA ATRHRVCSCP APQQGGAGCP 3450
    GGLEGHGDTG MQLQHQECPS VPPCPEDGAW AAWGPWSGCG GCGGQAVRTR 3500
    SCSSPPARFG GLPCAGEARQ SRACPWATSS CPECAGGLVA FTCGKPCPHS 3550
    CEDLREDTAC MATPRCLPAC ACPHGQLLQD GDCVPPELCR CAWAPSKNGS 3600
    IWEQDGAVPM QELQPGETVQ RHCQNCTCKS GTLQCHAEPG CRADGGWSPW 3650
    GPWSPCSPGC QAGTQLASRQ CNNPTPQLGG RGCSGHSQRQ RPCPATEGCP 3700
    EEEPWGEWSP WGPCSASCGG GEQLRHRDCP PPGGCPGLAL QSKTCNTHVC 3750
    REAGCPPGRL YRECQQGEGC PYSCAHLAGR IACFPGGCQE GCHCPTGTLL 3800
    HHGHCLQECP CVLTAEVLRK LRNSSADLQA APHLLGTRGP PLALDQELPP 3850
    GSTIHSACTS CTCLHGRLNC SEPVCPRDGG FSPWGPWSSC SRSCGGLGVM 3900
    TRRRGCTNPE PARGGRDCAG PRSDSKYCQS PECPAVPTTE PGPGVAGAEE 3950
    EEGFGPWSPW SPCSKTCTHP ERPATKTRER PCVGTAVCSG DGFQEQPCNL 4000
    PLCSDVPPCQ GEDCAGLNCS WAPWGPWTEC SRSCGVGRQQ RLRAYSPPGA 4050
    SGRWCPGILS AFVQRRFCSL QACKVDGAWS AWSPWSRCDR TCGGGRAVRT 4100
    RSCTRPPPKN GGQRCPGERH QLHLCNAQPC DDSCPPGMAL VTCANHCPRH 4150
    CGDLQEGIVC REEEHCEPGC RCPNGTLEQD GGCVPLAHCE CTDAQGHGWV 4200
    PGSTHHDGCN NCTCLEGRLR CTDRLCPPLR CPWSRWSRWS PCSVTCGDGQ 4250
    QTRFRTPTAG SWDEECQGEQ MENRGCAAGP CPPLCPQGSW ERRLGDMWLQ 4300
    GECQRCTCTP EGTVCEDTTC AGAEHCTWGT WSPCSRSCGT GLASREGSCP 4350
    CPFPGPPGAV CNASTGDGAR PHREVQACYL RPCPAECSWS AWSSWGGCSC 4400
    SSPLQHRYRH RHGTGLCVGL DVELHPCNTS GCSESSCEPP FEFQPCSPPC 4450
    ARLCSTLQHP ELCPAQSHCL PGCFCPQGLL EQRSACVPPE QCDCLHTNES 4500
    GDLVTLSPGD IILLGCKECV CQDGALQCSS EGCQGLLPLS PWSEWTPCST 4550
    CLPLFPSHLG DATPHVSVQH RYRACLDPQS GQPWSGDTAV CSAELQQQRL 4600
    CPDPDICQEL CLWSPWGPWG PCQQPCSGSF RLRHRHLQRL AGSGQCQGAQ 4650
    TQSESCNTAV CPGEDCEKQG RVFATTCANS CPRACADLWQ HVECVQGGCK 4700
    PGCRCPQGQL LQDGLCVPTA QCRCGLSGDN GTQELWPGQE ATIECHNCTC 4750
    ENGTMVCPAL PCPSYGPWST WSPCSSSCGS GRTSRHRTCE PNPGGVPCMA 4800
    SGMQETAECS PQPCPAGCQL SPWSPWSPCS SSCGGGRSER SRELLGGEEE 4850
    PCPIPALRQH RVCNVHNCTQ ECPRSQVHRE CANACPHACA DLRPQTQCLP 4900
    QPCQPGCACP PGQVLQDGAC VPPEECRCTL DSTMPGVLNL SREEQEQEHA 4950
    PGSRLQHRCN TCICIRGTFN CSQEECNVDC LWSPWSPWSP CSVTCGMGER 5000
    LSHRHPLRQR LYEGAECLGP PVRRAACHLP DCACPEGERW QGHEVPPGCE 5050
    QSCRDILDET PANCTPSPSP GCTCEPGHYR NSSGHCVPST LCECLHQGQL 5100
    HQPGSEWQEQ CARCRCVDGK ANCTDGCTPL SCPEGEVKVR EPGRCCPVCR 5150
    MEWPEEPSSM CRRFTELRNI TKGPCSLPNV EVSFCSGRCP SRTAVTPEEP 5200
    YLQTLCECCS YRLDPGSPVR ILSLPCAGGA AEPVVLPIIH SCECSSCQGG 5250
    DFSKR 5255
    Length:5,255
    Mass (Da):560,556
    Last modified:February 7, 2006 - v1
    Checksum:iDBE892EA9AA0378B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ866919 mRNA. Translation: CAI29216.1.
    RefSeqiNP_001006351.2. NM_001006351.2.
    UniGeneiGga.33700.
    Gga.52789.

    Genome annotation databases

    GeneIDi420367.
    KEGGigga:420367.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ866919 mRNA. Translation: CAI29216.1 .
    RefSeqi NP_001006351.2. NM_001006351.2.
    UniGenei Gga.33700.
    Gga.52789.

    3D structure databases

    ProteinModelPortali Q2PC93.
    SMRi Q2PC93. Positions 3059-3085.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000038585.

    Proteomic databases

    PaxDbi Q2PC93.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 420367.
    KEGGi gga:420367.

    Organism-specific databases

    CTDi 23145.

    Phylogenomic databases

    eggNOGi NOG12793.
    HOVERGENi HBG080794.
    PhylomeDBi Q2PC93.

    Miscellaneous databases

    NextBioi 20823284.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    4.10.400.10. 13 hits.
    InterProi IPR000421. Coagulation_fac_5/8-C_type_dom.
    IPR006207. Cys_knot_C.
    IPR008979. Galactose-bd-like.
    IPR023415. LDLR_class-A_CS.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR000884. Thrombospondin_1_rpt.
    IPR002919. TIL_dom.
    IPR014853. Unchr_dom_Cys-rich.
    IPR001007. VWF_C.
    IPR001846. VWF_type-D.
    [Graphical view ]
    Pfami PF08742. C8. 3 hits.
    PF00754. F5_F8_type_C. 1 hit.
    PF00057. Ldl_recept_a. 11 hits.
    PF01826. TIL. 13 hits.
    PF00090. TSP_1. 25 hits.
    PF00093. VWC. 1 hit.
    PF00094. VWD. 3 hits.
    [Graphical view ]
    PRINTSi PR00261. LDLRECEPTOR.
    SMARTi SM00832. C8. 3 hits.
    SM00231. FA58C. 1 hit.
    SM00192. LDLa. 13 hits.
    SM00209. TSP1. 27 hits.
    SM00214. VWC. 5 hits.
    SM00216. VWD. 3 hits.
    [Graphical view ]
    SUPFAMi SSF49785. SSF49785. 1 hit.
    SSF57424. SSF57424. 12 hits.
    SSF57567. SSF57567. 15 hits.
    SSF82895. SSF82895. 25 hits.
    PROSITEi PS01225. CTCK_2. 1 hit.
    PS01285. FA58C_1. 1 hit.
    PS01286. FA58C_2. 1 hit.
    PS50022. FA58C_3. 1 hit.
    PS01209. LDLRA_1. 11 hits.
    PS50068. LDLRA_2. 13 hits.
    PS50092. TSP1. 27 hits.
    PS01208. VWFC_1. 1 hit.
    PS50184. VWFC_2. 2 hits.
    PS51233. VWFD. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of SCO-spondin in chick embryos."
      Didier R.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: CNS.

    Entry informationi

    Entry nameiSSPO_CHICK
    AccessioniPrimary (citable) accession number: Q2PC93
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2006
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3