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Q2P674 (PUR5_XANOM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine cyclo-ligase
EC=6.3.3.1
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene names
Name:purM
Ordered Locus Names:XOO1198
OrganismXanthomonas oryzae pv. oryzae (strain MAFF 311018) [Complete proteome] [HAMAP]
Taxonomic identifier342109 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas ›

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. HAMAP-Rule MF_00741

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. HAMAP-Rule MF_00741

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00741.

Sequence similarities

Belongs to the AIR synthase family.

Ontologies

Keywords
   Biological processPurine biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' IMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoribosylformylglycinamidine cyclo-ligase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341Phosphoribosylformylglycinamidine cyclo-ligase HAMAP-Rule MF_00741
PRO_0000258432

Sequences

Sequence LengthMass (Da)Tools
Q2P674 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 84F6800ECDA0B36F

FASTA34135,824
        10         20         30         40         50         60 
MTYRDAGVDI DAGNALVERI KPLVKRSFRP EVMGGLGGFG ALFDLSGKYK EPVLVSGTDG 

        70         80         90        100        110        120 
VGTKLKLAQQ LGRHDTIGID LVGMCVNDVL VQGAEPLFFL DYFATGKLDV DTAAAVVGGI 

       130        140        150        160        170        180 
ARGCALSGCA LIGGETAEMP DMYPPGEYDL AGFTVGAVEK SQLLDGAQVR DGDVLIGIAS 

       190        200        210        220        230        240 
SGPHSNGYSL IRKIYERAGA PAEHVLDDGT KLIDALMAPT ALYVKPVLAL LKSHGQAIHA 

       250        260        270        280        290        300 
MAHITGGGLT ENIIRVIPDG LGLDIDASAW TLPPVFAWLQ REGAVADAEM WRTFNCGIGF 

       310        320        330        340 
VLIAAPAEAA ALEQALDAQS LAHWRIGQVV PAHGDERVRI D

« Hide

References

[1]"Genome sequence of Xanthomonas oryzae pv. oryzae suggests contribution of large numbers of effector genes and insertion sequences to its race diversity."
Ochiai H., Inoue Y., Takeya M., Sasaki A., Kaku H.
Jpn. Agric. Res. Q. 39:275-287(2005)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MAFF 311018.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008229 Genomic DNA. Translation: BAE67953.1.
RefSeqYP_450227.1. NC_007705.1.

3D structure databases

ProteinModelPortalQ2P674.
SMRQ2P674. Positions 1-341.
ModBaseSearch...

Protein-protein interaction databases

STRING342109.XOO_1198.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE67953; BAE67953; BAE67953.
GeneID3857780.
KEGGxom:XOO_1198.
PATRIC24111857. VBIXanOry49434_1360.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0150.
HOGENOMHOG000228645.
KOK01933.
OMAPRVLPKH.
ProtClustDBPRK05385.

Enzyme and pathway databases

BioCycXORY342109:GIX9-1222-MONOMER.
UniPathwayUPA00074; UER00129.

Family and domain databases

Gene3D3.90.650.10. 1 hit.
HAMAPMF_00741_B. AIRS_B.
InterProIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMSSF56042. AIR_synth_C. 1 hit.
SSF55326. PurM_N-like. 1 hit.
TIGRFAMsTIGR00878. purM. 1 hit.
ProtoNetSearch...

Entry information

Entry namePUR5_XANOM
AccessionPrimary (citable) accession number: Q2P674
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: February 7, 2006
Last modified: May 29, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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