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Protein

Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Gene

cobT

Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).UniRule annotation

Catalytic activityi

Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5'-phosphate.UniRule annotation

Pathwayi: alpha-ribazole biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes alpha-ribazole from 5,6-dimethylbenzimidazole.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (cobT)
  2. no protein annotated in this organism
This subpathway is part of the pathway alpha-ribazole biosynthesis, which is itself part of Nucleoside biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes alpha-ribazole from 5,6-dimethylbenzimidazole, the pathway alpha-ribazole biosynthesis and in Nucleoside biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei316Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCobalamin biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00061; UER00516

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseUniRule annotation (EC:2.4.2.21UniRule annotation)
Short name:
NN:DBI PRTUniRule annotation
Alternative name(s):
N(1)-alpha-phosphoribosyltransferaseUniRule annotation
Gene namesi
Name:cobTUniRule annotation
Ordered Locus Names:XOO1241
OrganismiXanthomonas oryzae pv. oryzae (strain MAFF 311018)
Taxonomic identifieri342109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000216421 – 348Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseAdd BLAST348

Proteomic databases

PRIDEiQ2P631

Structurei

3D structure databases

ProteinModelPortaliQ2P631
SMRiQ2P631
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CobT family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000137933
KOiK00768
OMAiQMATFAE
OrthoDBiPOG091H0031

Family and domain databases

CDDicd02439 DMB-PRT_CobT, 1 hit
Gene3Di1.10.1610.10, 2 hits
HAMAPiMF_00230 CobT, 1 hit
InterProiView protein in InterPro
IPR003200 Nict_dMeBzImd_PRibTrfase-like
IPR023195 Nict_dMeBzImd_PRibTrfase_N
IPR017846 Nict_dMeBzImd_PRibTrfase_pro
IPR036087 Nict_dMeBzImd_PRibTrfase_sf
PfamiView protein in Pfam
PF02277 DBI_PRT, 1 hit
SUPFAMiSSF52733 SSF52733, 1 hit
TIGRFAMsiTIGR03160 cobT_DBIPRT, 1 hit

Sequencei

Sequence statusi: Complete.

Q2P631-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNDWIFGAC AVPDARMRSA ALARQEQLTK PPGALGRLEQ LAVQLAAWQR
60 70 80 90 100
TEHPAVQRVW IAVYAADHGV AAEGVSAFPQ AVTGEMVRNF ARGGAAIAVL
110 120 130 140 150
ARELGARLEV VNLGVVNDPG DLSRVRRAWI APSTANICEQ PAMTATQLRD
160 170 180 190 200
ALAAGAHSIA QAKGCDTQLF VGGEMGIGNT TAAAALGCAL LSQFPQALAG
210 220 230 240 250
AGTGLDAEGI AHKVTVITRA LALHADASTP LERLRRLGGF EIAALVGAYI
260 270 280 290 300
AAAQAGIPVL VDGFIATAAA LVASRLNPGV REWLLFGHRS QERGHAALLR
310 320 330 340
ALDAEPLLQL DLRLGEASGA AVAIPLLRSA CALHNGMATF AEAGVSDA
Length:348
Mass (Da):35,924
Last modified:February 7, 2006 - v1
Checksum:iACBD1FF408F420FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008229 Genomic DNA Translation: BAE67996.1
RefSeqiWP_011407923.1, NC_007705.1

Genome annotation databases

EnsemblBacteriaiBAE67996; BAE67996; BAE67996
KEGGixom:XOO1241

Entry informationi

Entry nameiCOBT_XANOM
AccessioniPrimary (citable) accession number: Q2P631
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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