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Q2P4B8

- LPXB_XANOM

UniProt

Q2P4B8 - LPXB_XANOM

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Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciXORY342109:GIX9-1880-MONOMER.
UniPathwayiUPA00359; UER00481.

Protein family/group databases

CAZyiGT19. Glycosyltransferase Family 19.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:XOO1854
OrganismiXanthomonas oryzae pv. oryzae (strain MAFF 311018)
Taxonomic identifieri342109 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
ProteomesiUP000001957: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 432432Lipid-A-disaccharide synthasePRO_0000255235Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342109.XOO_1854.

Structurei

3D structure databases

ProteinModelPortaliQ2P4B8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000219861.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2P4B8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTGIGNQTSG IETGVHDRAP ADGEPTALPI SHSPLPIPGA HARPPRFALI
60 70 80 90 100
AGEASGDILG AGLIAQLRLR YPNAEFVGIG GDAMRGAGCQ TWFDASELAV
110 120 130 140 150
MGLTEVLRHL PRLLKLRSAF RERVLAWKPD VFIGIDAPDF NLPVERWLKQ
160 170 180 190 200
RGIKTVHYVS PSVWAWREKR AEKIAVSADL VLCLFPMEPP IYAKHGVDAR
210 220 230 240 250
FVGHPMADDI AYQADRDAAR ATLGLSASST VLAVLPGSRH GEISRLGDTF
260 270 280 290 300
LQAAWLVCEH IPNLHVLVPA ANAGCKQLLA EQLSRSSLPV MRSHLINGQA
310 320 330 340 350
RTAMLAADVV LLASGTATLE AMLVKRPMVV GYKVAPLTYR IVKLLGLIKV
360 370 380 390 400
NRYALPNILA NDDLAPELMQ DDCMPERLCV ALLDWLKHPA KVAALQPRYL
410 420 430
ALHAALRRDA SARAAEAVAG LLQGRDWSGA NI
Length:432
Mass (Da):46,688
Last modified:February 7, 2006 - v1
Checksum:iDD206C883AF08D24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008229 Genomic DNA. Translation: BAE68609.1.
RefSeqiWP_011258688.1. NC_007705.1.
YP_450883.1. NC_007705.1.

Genome annotation databases

EnsemblBacteriaiBAE68609; BAE68609; BAE68609.
GeneIDi3856856.
KEGGixom:XOO_1854.
PATRICi24113309. VBIXanOry49434_2083.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008229 Genomic DNA. Translation: BAE68609.1 .
RefSeqi WP_011258688.1. NC_007705.1.
YP_450883.1. NC_007705.1.

3D structure databases

ProteinModelPortali Q2P4B8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 342109.XOO_1854.

Protein family/group databases

CAZyi GT19. Glycosyltransferase Family 19.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE68609 ; BAE68609 ; BAE68609 .
GeneIDi 3856856.
KEGGi xom:XOO_1854.
PATRICi 24113309. VBIXanOry49434_2083.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000219861.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci XORY342109:GIX9-1880-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Xanthomonas oryzae pv. oryzae suggests contribution of large numbers of effector genes and insertion sequences to its race diversity."
    Ochiai H., Inoue Y., Takeya M., Sasaki A., Kaku H.
    Jpn. Agric. Res. Q. 39:275-287(2005)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MAFF 311018.

Entry informationi

Entry nameiLPXB_XANOM
AccessioniPrimary (citable) accession number: Q2P4B8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: February 7, 2006
Last modified: November 26, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3