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Q2NYM7 (HGD_XANOM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Homogentisate 1,2-dioxygenase

EC=1.13.11.5
Alternative name(s):
Homogentisate oxygenase
Homogentisic acid oxidase
Homogentisicase
Gene names
Name:hmgA
Ordered Locus Names:XOO3845
OrganismXanthomonas oryzae pv. oryzae (strain MAFF 311018) [Complete proteome] [HAMAP]
Taxonomic identifier342109 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas

Protein attributes

Sequence length441 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Homogentisate + O2 = 4-maleylacetoacetate. HAMAP MF_00334

Cofactor

Iron By similarity. HAMAP MF_00334

Pathway

Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6. HAMAP MF_00334

Sequence similarities

Belongs to the homogentisate dioxygenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 441441Homogentisate 1,2-dioxygenase HAMAP MF_00334
PRO_1000019545

Sites

Metal binding3301Iron By similarity
Metal binding3361Iron By similarity
Metal binding3661Iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2NYM7 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 05CF74A5847A7698

FASTA44148,542
        10         20         30         40         50         60 
MHNPQHYMTG FGNEFATEAV AGSLPVGQNS PQRVAHGLYA EQLSGTAFTA PRGENRRSWL 

        70         80         90        100        110        120 
YRIRPAAVHG RFSLIEQSRL HNDFGGGPVP PDQMRWSPLP LPATPTDFVD GLYTMAGNGS 

       130        140        150        160        170        180 
PEAMTGVAVH LYAANASMHG RFFYNADGEL LLVPQLGRLR VCTELGVLEL EPQQIGVIPR 

       190        200        210        220        230        240 
GVRFRVELLD SAARGYVCEN FGGLLRLPDL GPIGANGLAN PRDFETPRAA FEQRDGAFEL 

       250        260        270        280        290        300 
VAKFQGHLWR ADIDHSPLDV VAWHGNYAPY RYDLRRFNTI GSISFDHPDP SIFTVLTSPS 

       310        320        330        340        350        360 
DTHGTANMDF AIFPPRWLVA QHTFRPPWFH RNVASEFMGL VHGVYDAKAE GFAPGGASLH 

       370        380        390        400        410        420 
NCMSGHGPDA ATFDKASQAD LTRPDVIAET MAFMFETRAV LRPTQQALSA AHRQADYQQC 

       430        440 
WSGLRAAFQH PPAKNTTSVL R 

« Hide

References

[1]"Genome sequence of Xanthomonas oryzae pv. oryzae suggests contribution of large numbers of effector genes and insertion sequences to its race diversity."
Ochiai H., Inoue Y., Takeya M., Sasaki A., Kaku H.
Jpn. Agric. Res. Q. 39:275-287(2005)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MAFF 311018.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008229 Genomic DNA. Translation: BAE70600.1.
RefSeqYP_452874.1. NC_007705.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2NYM7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3858339.
GenomeReviewsGene locus XOO3845 in contig AP008229_GR.
KEGGxom:XOO_3845.
PATRIC24117980. VBIXanOry49434_4390.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3508.
HOGENOMHBG293508.
OMARNCMSEF.
ProtClustDBPRK05341.

Enzyme and pathway databases

BioCycXORY342109:XOO3845-MONOMER.

Family and domain databases

HAMAPMF_00334. Homogentis_dioxygen.
[Tree]
InterProIPR011051. Cupin_RmlC_type.
IPR005708. Homogentis_dOase.
IPR022950. Homogentis_dOase_bac.
[Graphical view]
KOK00451.
PANTHERPTHR11056. Homogentis_dOase. 1 hit.
PfamPF04209. HgmA. 1 hit.
[Graphical view]
SUPFAMSSF51182. RmlC_like_cupin. 1 hit.
TIGRFAMsTIGR01015. HmgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameHGD_XANOM
AccessionPrimary (citable) accession number: Q2NYM7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families