Reviewed, UniProtKB/Swiss-Prot Q2NW90 (SYK3_SODGM)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Ordered Locus Names:	SG0310

Organism

Sodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]

Taxonomic identifier

343509 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Sodalis

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 325	325	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_1000023632

Sequences

	Sequence		Length	Mass (Da)
	Q2NW90-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: F2EF00900C4408B5	FASTA	325	36,453
	10 20 30 40 50 60 MSDSASWQPS APIANLLKRA AIVGQIRRFF SDRGLLEVET PAMSQATVTD IHLVPFQTCF 70 80 90 100 110 120 IGPGAAGGMP LYLMTSPEYH MKRLLAAGSG PLFQLCRSFR NEEAGRYHNP EFTMLEWYRP 130 140 150 160 170 180 HYDMYRLMNE VDDLLQQILD CDSAETLSYQ QVFTRHVGID PLSADKAQLY DAAVKWDLGE 190 200 210 220 230 240 AASVEDDRDT LLQLLFAMVV EPNIGHDKPA FVYHFPASQA ALAEISTEDH RVADRFEAYF 250 260 270 280 290 300 KGIELANGFC ELTDAREQRQ RFEQDNRKRV AMKLSEQPID ENLLAALAQG MPECSGVALG 310 320 VDRLVMLALK ADRLSDVIAF AVERA

References

[1]

"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host." Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S. Genome Res. 16:149-156(2006) [PubMed: 16365377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP008232 Genomic DNA. Translation: BAE73585.1.
RefSeq	YP_453990.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3868578.
GenomeReviews	Gene locus SG0310 in contig AP008232_GR.
KEGG	sgl:SG0310.
NMPDR	fig|343509.6.peg.725.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q2NW90.
OMA	Q2NW90. VFRNEEA.
Enzyme and pathway databases
BioCyc	SGLO343509:SG0310-MON.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_SODGM

Accession

Primary (citable) accession number: Q2NW90

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)