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Q2NUK0

- 6PGL_SODGM

UniProt

Q2NUK0 - 6PGL_SODGM

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Protein

6-phosphogluconolactonase

Gene
pgl, SG0900
Organism
Sodalis glossinidius (strain morsitans)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciSGLO343509:GJJC-942-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6-P-gluconolactonase
Gene namesi
Name:pgl
Ordered Locus Names:SG0900
OrganismiSodalis glossinidius (strain morsitans)
Taxonomic identifieri343509 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis
ProteomesiUP000001932: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3313316-phosphogluconolactonaseUniRule annotationPRO_0000291473Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi343509.SG0900.

Structurei

3D structure databases

ProteinModelPortaliQ2NUK0.
SMRiQ2NUK0. Positions 1-330.

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiPMVIAPN.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NUK0-1 [UniParc]FASTAAdd to Basket

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MKQIVYVASP ESQQIHVWQM DNQGALTLLQ VVDTPGQGQP MVIHPARTHL    50
YIGVRPSFGV VSYRIDEKGL LTEAGMAPLP GSPTQLTTDL QGETLYSVSY 100
SGSCLSVSPI DEQGIVGAPT QTLEGLTHCH SANVDTTNQV LWVPCLQEDR 150
IRLYTIGEAG HLTPRTPEAL DSVAGAGPRH MVFHHGGGYA YAINELSGTV 200
NVIAIDAAGA GPRIVQTLDI MPAGFSDTRW AADIYITPDG RWLYCCDRTA 250
SVISRFAVSE DGGVLRLLGH QATESQPRGF NIDSQGRFLV AAGQKSHHIA 300
VYAIDAQSGA LDPLARYAVG QGPMWVSVLA R 331
Length:331
Mass (Da):35,497
Last modified:February 7, 2006 - v1
Checksum:iFBCA285148940C20
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008232 Genomic DNA. Translation: BAE74175.1.
RefSeqiYP_454580.1. NC_007712.1.

Genome annotation databases

EnsemblBacteriaiBAE74175; BAE74175; SG0900.
GeneIDi3868348.
KEGGisgl:SG0900.
PATRICi23649472. VBISodGlo61428_2044.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008232 Genomic DNA. Translation: BAE74175.1 .
RefSeqi YP_454580.1. NC_007712.1.

3D structure databases

ProteinModelPortali Q2NUK0.
SMRi Q2NUK0. Positions 1-330.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 343509.SG0900.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE74175 ; BAE74175 ; SG0900 .
GeneIDi 3868348.
KEGGi sgl:SG0900.
PATRICi 23649472. VBISodGlo61428_2044.

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000257418.
KOi K07404.
OMAi PMVIAPN.
OrthoDBi EOG615VK7.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci SGLO343509:GJJC-942-MONOMER.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
HAMAPi MF_01605. 6P_gluconolactonase.
InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
SUPFAMi SSF50974. SSF50974. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
    Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
    Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: morsitans.

Entry informationi

Entry namei6PGL_SODGM
AccessioniPrimary (citable) accession number: Q2NUK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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