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Q2NU84 (PNCB_SODGM) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:SG1016
OrganismSodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]
Taxonomic identifier343509 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000025016

Sequences

Sequence LengthMass (Da)Tools
Q2NU84 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 98F4B4CBAEE87F34

FASTA40246,361
        10         20         30         40         50         60 
MNVATDPILT SILDTDAYKF HMQQAVFHRY HDVMVSAKFR CRGYELLGEY AADISAQVDM 

        70         80         90        100        110        120 
MRGLQLNDDE FTYLRGLPFF QSDYLNCLRQ FRFDPSQVRI RNHHGKLDIR ITGPWRDVIL 

       130        140        150        160        170        180 
WEVPLLAVIS EVVHHRRSPQ VTTADAVARL RQKLLHFRRI SEDLDTSRFR LMDFGTRRRF 

       190        200        210        220        230        240 
SRQVQFEVIA ELQREFPYLI GTSNYQLARE RGLPPIGTQA HEWFQAHQQI SPDLANSQSA 

       250        260        270        280        290        300 
ALQAWLDEYP DRLGIALTDC ITMDAFLRDF GPSFARAYQG MRHDSGDPVE WGEKAIAHYQ 

       310        320        330        340        350        360 
QLGIDPLTKT LVFSDSLDFD KAFMLYRHFW QRINLVFGIG TRLTCDIPGI KPLNIVIKLV 

       370        380        390        400 
KCNGKPVAKL SDSPGKIMCH DKAFVRALRK AFDVPLVVKK AS 

« Hide

References

[1]"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: morsitans.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008232 Genomic DNA. Translation: BAE74291.1.
RefSeqYP_454696.1. NC_007712.1.

3D structure databases

ProteinModelPortalQ2NU84.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING343509.SG1016.

Proteomic databases

PRIDEQ2NU84.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE74291; BAE74291; SG1016.
GeneID3866380.
KEGGsgl:SG1016.
PATRIC23650034. VBISodGlo61428_2327.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycSGLO343509:GJJC-1058-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_SODGM
AccessionPrimary (citable) accession number: Q2NU84
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: June 11, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways