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Q2NTK2 (SYR_SODGM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:SG1248
OrganismSodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]
Taxonomic identifier343509 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis

Protein attributes

Sequence length576 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 576576Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242094

Regions

Motif122 – 13211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q2NTK2 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: BD5FEDD88FE7F033

FASTA57663,717
        10         20         30         40         50         60 
MNIHTLLSEK IQQALVAAGA PADCEAQVRQ SAKAQFGDYQ ANGVMAIAKQ LGLPPRKLAE 

        70         80         90        100        110        120 
NVVGLLNLDG IARKVDIAGP GFINIFLEPS WLANHLAAAL SSPRLGIASV ASQTIVVDYS 

       130        140        150        160        170        180 
APNVAKEMHV GHVRSTIIGD ASVRTLSFLG HNVIRANHVG DWGTQFGMLI AYLEKVQDGG 

       190        200        210        220        230        240 
EAEMQLSSLE SFYRAAKQHY DEDPAFAERA RGYVVKLQGG DEYCRQMWRK LVDVTMAQNQ 

       250        260        270        280        290        300 
KTYNRLNVTL TRADVMGESL YNDMLPGIVA DLKAKGLAVE SEGATVVFLD EFKNKEGEPM 

       310        320        330        340        350        360 
GVIIQKKDGA YLYTTTDIAC AKYRYETLKA DRIIYYIDSR QHQHLMLAWT IVRKAGYVPE 

       370        380        390        400        410        420 
SVPLEHHMFG MMLGKDGKPF KTRAGGTIKL TELLDEALER ARRLVAAKNP SMDAGELARL 

       430        440        450        460        470        480 
AQVVGIGAVK YADLSKSRTT DYVFDWDNML SFEGNTAPYM QYAYTRVASI FKRSGQDEQQ 

       490        500        510        520        530        540 
LTGDIRLEAE QETQLAVRLL QLEEAIATVA RDGTPHVLCA YLYDLAVLFS AFYEHCPILN 

       550        560        570 
AENAALRQSR LQLALLTART LKKGLDLLGI ETVERM 

« Hide

References

[1]"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: morsitans.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008232 Genomic DNA. Translation: BAE74523.1.
RefSeqYP_454928.1. NC_007712.1.

3D structure databases

ProteinModelPortalQ2NTK2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING343509.SG1248.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE74523; BAE74523; SG1248.
GeneID3866771.
KEGGsgl:SG1248.
PATRIC23651214. VBISodGlo61428_2906.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMADIMAESA.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycSGLO343509:GJJC-1299-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SODGM
AccessionPrimary (citable) accession number: Q2NTK2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries