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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Sodalis glossinidius (strain morsitans)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:SG1751
OrganismiSodalis glossinidius (strain morsitans)
Taxonomic identifieri343509 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaeSodalis
Proteomesi
  • UP000001932 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003255131 – 539Probable malate:quinone oxidoreductaseAdd BLAST539

Interactioni

Protein-protein interaction databases

STRINGi343509.SG1751.

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
KOiK00116.
OMAiRGMEISE.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NS49-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKENFIAALG MTVSASAKQH QVVDNPPVDI ILIGGGVMSA TLGTYLKALE
60 70 80 90 100
PGWTIHMYER LEKTAEESSN GWNNAGTGHA AFCELNYTTL SPAGSVDISK
110 120 130 140 150
AVAVNESFEI SRQFWAYLVK QKILTNPQSF INNVPHMSFV WGEDNIRFLR
160 170 180 190 200
QRFDALQTST LFRGMEYSEN PQQIREWAPL VMDGRDTFQK VAATRMAMGT
210 220 230 240 250
DVNFGEMTQQ LLAALQQYPQ FHLHLQHDVV DIKRNADQTW SVRVADHSNG
260 270 280 290 300
GRQSTVCARH VFIGGGGASL TLLQKSGIPE VNGYAGFPVG GQFLVATNPE
310 320 330 340 350
VVGHHHAKVY GKASVGAPPM SVPHIDTRIL DGKQALLFGP FATFSSKFLK
360 370 380 390 400
RGSWLDLFHS LTRQNLLPML RVGLDNFGLM RYLIGQLLMS DKDRLNALRE
410 420 430 440 450
YYPQATMADW SLIEAGQRVQ VIKKDAGKGG ILQFGTEVVS SADGSLSVLL
460 470 480 490 500
GASPGASTAA PIMLELLASM FKEQVTTDAW QRKLKEMVPS YGQTINGNLA
510 520 530
LTNEIRLSTS EVLGLTYIEA KPLPGEPADG KWEGLQKAM
Length:539
Mass (Da):59,147
Last modified:February 7, 2006 - v1
Checksum:i927BF35D8FD87A5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008232 Genomic DNA. Translation: BAE75026.1.
RefSeqiWP_011411575.1. NC_007712.1.

Genome annotation databases

EnsemblBacteriaiBAE75026; BAE75026; SG1751.
KEGGisgl:SG1751.

Similar proteinsi

Entry informationi

Entry nameiMQO_SODGM
AccessioniPrimary (citable) accession number: Q2NS49
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: February 7, 2006
Last modified: October 25, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families