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Q2NS49 (MQO_SODGM) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:SG1751
OrganismSodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]
Taxonomic identifier343509 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Sodalis

Protein attributes

Sequence length539 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 539539Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_0000325513

Sequences

Sequence LengthMass (Da)Tools
Q2NS49 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 927BF35D8FD87A5D

FASTA53959,147
        10         20         30         40         50         60 
MKENFIAALG MTVSASAKQH QVVDNPPVDI ILIGGGVMSA TLGTYLKALE PGWTIHMYER 

        70         80         90        100        110        120 
LEKTAEESSN GWNNAGTGHA AFCELNYTTL SPAGSVDISK AVAVNESFEI SRQFWAYLVK 

       130        140        150        160        170        180 
QKILTNPQSF INNVPHMSFV WGEDNIRFLR QRFDALQTST LFRGMEYSEN PQQIREWAPL 

       190        200        210        220        230        240 
VMDGRDTFQK VAATRMAMGT DVNFGEMTQQ LLAALQQYPQ FHLHLQHDVV DIKRNADQTW 

       250        260        270        280        290        300 
SVRVADHSNG GRQSTVCARH VFIGGGGASL TLLQKSGIPE VNGYAGFPVG GQFLVATNPE 

       310        320        330        340        350        360 
VVGHHHAKVY GKASVGAPPM SVPHIDTRIL DGKQALLFGP FATFSSKFLK RGSWLDLFHS 

       370        380        390        400        410        420 
LTRQNLLPML RVGLDNFGLM RYLIGQLLMS DKDRLNALRE YYPQATMADW SLIEAGQRVQ 

       430        440        450        460        470        480 
VIKKDAGKGG ILQFGTEVVS SADGSLSVLL GASPGASTAA PIMLELLASM FKEQVTTDAW 

       490        500        510        520        530 
QRKLKEMVPS YGQTINGNLA LTNEIRLSTS EVLGLTYIEA KPLPGEPADG KWEGLQKAM

« Hide

References

[1]"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
Genome Res. 16:149-156(2006) [PubMed: 16365377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: morsitans.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008232 Genomic DNA. Translation: BAE75026.1.
RefSeqYP_455431.1. NC_007712.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2NS49.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3866496.
GenomeReviewsGene locus SG1751 in contig AP008232_GR.
KEGGsgl:SG1751.
NMPDRfig|343509.6.peg.3736.
PATRIC23653815. VBISodGlo61428_4194.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMAATFSTKY.
PhylomeDBQ2NS49.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycSGLO343509:SG1751-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_SODGM
AccessionPrimary (citable) accession number: Q2NS49
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: February 7, 2006
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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