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Q2NRD3 (SPEB_SODGM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Agmatinase

EC=3.5.3.11
Alternative name(s):
Agmatine ureohydrolase
Short name=AUH
Gene names
Name:speB
Ordered Locus Names:SG2017
OrganismSodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]
Taxonomic identifier343509 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of putrescine from agmatine By similarity. HAMAP-Rule MF_01418

Catalytic activity

Agmatine + H2O = putrescine + urea. HAMAP-Rule MF_01418

Cofactor

Manganese By similarity. HAMAP-Rule MF_01418

Pathway

Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine: step 1/1. HAMAP-Rule MF_01418

Sequence similarities

Belongs to the arginase family. Agmatinase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 307307Agmatinase HAMAP-Rule MF_01418
PRO_1000024288

Sites

Metal binding1261Manganese By similarity
Metal binding1491Manganese By similarity
Metal binding1511Manganese By similarity
Metal binding1531Manganese By similarity
Metal binding2301Manganese By similarity
Metal binding2321Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2NRD3 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 709F31E00C181ED5

FASTA30733,526
        10         20         30         40         50         60 
MTTLGHNYDN SLVSNAFGFL RLPLEFNPYA TDADWVITGI PFDMATSGRA GCRHGPAAIR 

        70         80         90        100        110        120 
QVSTNLAWEG CRWPWDFDVR KRLKVVDCGD LVYEFGDAQD FCDKLQDHAE RLLAAGKRML 

       130        140        150        160        170        180 
SFGGDHFVTL PLLCAHAKHF GKMALVHFDA HTDTYANGSK FDHGSMFYHA PNEGLISPAH 

       190        200        210        220        230        240 
SVQIGIRTEF ERDNGFTVLD AGQVNDRSVD DILAQVKQIV GNLPVYLTFD IDCLDPSAAP 

       250        260        270        280        290        300 
GTGTPVIGGL TSDRALKLVR GLQPLNIVGM DIVEVAPAYD QAQITALVAA TLALEMLYIQ 


GAKRGDD 

« Hide

References

[1]"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: morsitans.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008232 Genomic DNA. Translation: BAE75292.1.
RefSeqYP_455697.1. NC_007712.1.

3D structure databases

ProteinModelPortalQ2NRD3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING343509.SG2017.

Proteomic databases

PRIDEQ2NRD3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE75292; BAE75292; SG2017.
GeneID3868796.
KEGGsgl:SG2017.
PATRIC23655176. VBISodGlo61428_4869.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0010.
KOK01480.
OMAKPDYSLY.
OrthoDBEOG6R2GW5.

Enzyme and pathway databases

BioCycSGLO343509:GJJC-2086-MONOMER.
UniPathwayUPA00534; UER00287.

Family and domain databases

Gene3D3.40.800.10. 1 hit.
HAMAPMF_01418. SpeB.
InterProIPR023694. Agmatinase.
IPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERPTHR11358. PTHR11358. 1 hit.
PfamPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFPIRSF036979. Arginase. 1 hit.
TIGRFAMsTIGR01230. agmatinase. 1 hit.
PROSITEPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEB_SODGM
AccessionPrimary (citable) accession number: Q2NRD3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: May 14, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways