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Q2NR04 (G6PI_SODGM) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:SG2146
OrganismSodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]
Taxonomic identifier343509 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252646

Sites

Active site3551Proton donor By similarity
Active site3861 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q2NR04 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: C76B27D0EB0E67CA

FASTA54961,552
        10         20         30         40         50         60 
MKDINPSHTA AWKALQQHFA TMKDVQISDL FAQEPERFSS FSATFNDQML VDYSKNRITA 

        70         80         90        100        110        120 
ETLTRLLALA EECGVKEAIA AMFSGEKINR TEDRAVLHVA LRNRSNTPIN VDDKDVMPDV 

       130        140        150        160        170        180 
NAVLVKMKQF CDRVIGGEWK GYTGRIITDI VNIGIGGSDL GPYMVTEALR PYKNHLNMHY 

       190        200        210        220        230        240 
VSNVDGTHIA ETIKDLDPAT TLFLVASKTF TTQETMTNAH SARDWFLKTA GDEQHVARHF 

       250        260        270        280        290        300 
AALSTNAKAV AEFGIDTENM FEFWDWVGGR YSLWSAIGLS IALSLGFDNF EKLLSGAHAM 

       310        320        330        340        350        360 
DHHFVSTPLD KNLPVLLALI GIWYNNFFGM ETEAILPYDQ YMHRFAAYFQ QGNMESNGKY 

       370        380        390        400        410        420 
VDREGHPVSY QTGPIIWGEP GTNGQHSFYQ LIHQGTKIVP CDFIAPAISH NPLTDHHAKL 

       430        440        450        460        470        480 
LSNFFAQTEA LAFGKSREAV EQEFSAAGKS PDQVQHVAPF KVFEGNRPTN SILLREITPY 

       490        500        510        520        530        540 
SLGALIALYE HKIFTQGAIL NIYTFDQWGV ELGKQLANRI LPELAQDNPI DAHDSSTNGL 


INRYKSWRH 

« Hide

References

[1]"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: morsitans.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008232 Genomic DNA. Translation: BAE75421.1.
RefSeqYP_455826.1. NC_007712.1.

3D structure databases

ProteinModelPortalQ2NR04.
SMRQ2NR04. Positions 12-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING343509.SG2146.

Proteomic databases

PRIDEQ2NR04.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE75421; BAE75421; SG2146.
GeneID3868255.
KEGGsgl:SG2146.
PATRIC23656007. VBISodGlo61428_5283.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycSGLO343509:GJJC-2217-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_SODGM
AccessionPrimary (citable) accession number: Q2NR04
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: February 7, 2006
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways