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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Sodalis glossinidius (strain morsitans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA), ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei355Proton donorUniRule annotation1
Active sitei386UniRule annotation1
Active sitei514UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSGLO343509:G1G2G-4115-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:SG2146
OrganismiSodalis glossinidius (strain morsitans)
Taxonomic identifieri343509 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaeSodalis
Proteomesi
  • UP000001932 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002526461 – 549Glucose-6-phosphate isomeraseAdd BLAST549

Proteomic databases

PRIDEiQ2NR04

Interactioni

Protein-protein interaction databases

STRINGi343509.SG2146

Structurei

3D structure databases

ProteinModelPortaliQ2NR04
SMRiQ2NR04
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.101 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q2NR04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDINPSHTA AWKALQQHFA TMKDVQISDL FAQEPERFSS FSATFNDQML
60 70 80 90 100
VDYSKNRITA ETLTRLLALA EECGVKEAIA AMFSGEKINR TEDRAVLHVA
110 120 130 140 150
LRNRSNTPIN VDDKDVMPDV NAVLVKMKQF CDRVIGGEWK GYTGRIITDI
160 170 180 190 200
VNIGIGGSDL GPYMVTEALR PYKNHLNMHY VSNVDGTHIA ETIKDLDPAT
210 220 230 240 250
TLFLVASKTF TTQETMTNAH SARDWFLKTA GDEQHVARHF AALSTNAKAV
260 270 280 290 300
AEFGIDTENM FEFWDWVGGR YSLWSAIGLS IALSLGFDNF EKLLSGAHAM
310 320 330 340 350
DHHFVSTPLD KNLPVLLALI GIWYNNFFGM ETEAILPYDQ YMHRFAAYFQ
360 370 380 390 400
QGNMESNGKY VDREGHPVSY QTGPIIWGEP GTNGQHSFYQ LIHQGTKIVP
410 420 430 440 450
CDFIAPAISH NPLTDHHAKL LSNFFAQTEA LAFGKSREAV EQEFSAAGKS
460 470 480 490 500
PDQVQHVAPF KVFEGNRPTN SILLREITPY SLGALIALYE HKIFTQGAIL
510 520 530 540
NIYTFDQWGV ELGKQLANRI LPELAQDNPI DAHDSSTNGL INRYKSWRH
Length:549
Mass (Da):61,552
Last modified:February 7, 2006 - v1
Checksum:iC76B27D0EB0E67CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008232 Genomic DNA Translation: BAE75421.1
RefSeqiWP_011411958.1, NC_007712.1

Genome annotation databases

EnsemblBacteriaiBAE75421; BAE75421; SG2146
KEGGisgl:SG2146

Similar proteinsi

Entry informationi

Entry nameiG6PI_SODGM
AccessioniPrimary (citable) accession number: Q2NR04
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: February 7, 2006
Last modified: February 28, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome