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Q2NR04

- G6PI_SODGM

UniProt

Q2NR04 - G6PI_SODGM

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, SG2146
Organism
Sodalis glossinidius (strain morsitans)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donor By similarity
Active sitei386 – 3861 By similarity
Active sitei514 – 5141 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciSGLO343509:GJJC-2217-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:SG2146
OrganismiSodalis glossinidius (strain morsitans)
Taxonomic identifieri343509 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis
ProteomesiUP000001932: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000252646Add
BLAST

Proteomic databases

PRIDEiQ2NR04.

Interactioni

Protein-protein interaction databases

STRINGi343509.SG2146.

Structurei

3D structure databases

ProteinModelPortaliQ2NR04.
SMRiQ2NR04. Positions 12-548.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2NR04-1 [UniParc]FASTAAdd to Basket

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MKDINPSHTA AWKALQQHFA TMKDVQISDL FAQEPERFSS FSATFNDQML    50
VDYSKNRITA ETLTRLLALA EECGVKEAIA AMFSGEKINR TEDRAVLHVA 100
LRNRSNTPIN VDDKDVMPDV NAVLVKMKQF CDRVIGGEWK GYTGRIITDI 150
VNIGIGGSDL GPYMVTEALR PYKNHLNMHY VSNVDGTHIA ETIKDLDPAT 200
TLFLVASKTF TTQETMTNAH SARDWFLKTA GDEQHVARHF AALSTNAKAV 250
AEFGIDTENM FEFWDWVGGR YSLWSAIGLS IALSLGFDNF EKLLSGAHAM 300
DHHFVSTPLD KNLPVLLALI GIWYNNFFGM ETEAILPYDQ YMHRFAAYFQ 350
QGNMESNGKY VDREGHPVSY QTGPIIWGEP GTNGQHSFYQ LIHQGTKIVP 400
CDFIAPAISH NPLTDHHAKL LSNFFAQTEA LAFGKSREAV EQEFSAAGKS 450
PDQVQHVAPF KVFEGNRPTN SILLREITPY SLGALIALYE HKIFTQGAIL 500
NIYTFDQWGV ELGKQLANRI LPELAQDNPI DAHDSSTNGL INRYKSWRH 549
Length:549
Mass (Da):61,552
Last modified:February 7, 2006 - v1
Checksum:iC76B27D0EB0E67CA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008232 Genomic DNA. Translation: BAE75421.1.
RefSeqiWP_011411958.1. NC_007712.1.
YP_455826.1. NC_007712.1.

Genome annotation databases

EnsemblBacteriaiBAE75421; BAE75421; SG2146.
GeneIDi3868255.
KEGGisgl:SG2146.
PATRICi23656007. VBISodGlo61428_5283.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008232 Genomic DNA. Translation: BAE75421.1 .
RefSeqi WP_011411958.1. NC_007712.1.
YP_455826.1. NC_007712.1.

3D structure databases

ProteinModelPortali Q2NR04.
SMRi Q2NR04. Positions 12-548.
ModBasei Search...

Protein-protein interaction databases

STRINGi 343509.SG2146.

Proteomic databases

PRIDEi Q2NR04.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE75421 ; BAE75421 ; SG2146 .
GeneIDi 3868255.
KEGGi sgl:SG2146.
PATRICi 23656007. VBISodGlo61428_5283.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci SGLO343509:GJJC-2217-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
    Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
    Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: morsitans.

Entry informationi

Entry nameiG6PI_SODGM
AccessioniPrimary (citable) accession number: Q2NR04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: February 7, 2006
Last modified: September 3, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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