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Q2NQS9

- KGUA_SODGM

UniProt

Q2NQS9 - KGUA_SODGM

Protein

Guanylate kinase

Gene

gmk

Organism
Sodalis glossinidius (strain morsitans)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Functioni

    Essential for recycling GMP and indirectly, cGMP.UniRule annotation

    Catalytic activityi

    ATP + GMP = ADP + GDP.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi11 – 188ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. guanylate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleotide metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSGLO343509:GJJC-2297-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
    Alternative name(s):
    GMP kinaseUniRule annotation
    Gene namesi
    Name:gmkUniRule annotation
    Ordered Locus Names:SG2221
    OrganismiSodalis glossinidius (strain morsitans)
    Taxonomic identifieri343509 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSodalis
    ProteomesiUP000001932: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 207207Guanylate kinasePRO_0000266405Add
    BLAST

    Proteomic databases

    PRIDEiQ2NQS9.

    Interactioni

    Protein-protein interaction databases

    STRINGi343509.SG2221.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2NQS9.
    SMRiQ2NQS9. Positions 3-207.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 184181Guanylate kinase-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the guanylate kinase family.UniRule annotation
    Contains 1 guanylate kinase-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0194.
    KOiK00942.
    OMAiMSHYNEY.
    OrthoDBiEOG6CP410.

    Family and domain databases

    Gene3Di3.40.50.300. 3 hits.
    HAMAPiMF_00328. Guanylate_kinase.
    InterProiIPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00625. Guanylate_kin. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2NQS9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIQGTLYIVS APSGAGKSSL IQALLKTQPL YDTQVSISHT TRAMRPGEAH    50
    GQHYFFVPVA EFEHMIAEDA FLEYARVFDN YYGTSREAIQ QVLATGVDVF 100
    LDIDWQGAQQ IRAKMPDARS IFVLPPSKEE LDRRLRGRDQ DSEEVIGRRM 150
    AQAVAEMTHF AEYDYLIVND DFNTALLDLK TIIRAERLRL GRQKLHHDAL 200
    ISKLLAD 207
    Length:207
    Mass (Da):23,496
    Last modified:February 7, 2006 - v1
    Checksum:i32A11A9E656AAD48
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008232 Genomic DNA. Translation: BAE75496.1.
    RefSeqiYP_455901.1. NC_007712.1.

    Genome annotation databases

    EnsemblBacteriaiBAE75496; BAE75496; SG2221.
    GeneIDi3868805.
    KEGGisgl:SG2221.
    PATRICi23656379. VBISodGlo61428_5464.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008232 Genomic DNA. Translation: BAE75496.1 .
    RefSeqi YP_455901.1. NC_007712.1.

    3D structure databases

    ProteinModelPortali Q2NQS9.
    SMRi Q2NQS9. Positions 3-207.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 343509.SG2221.

    Proteomic databases

    PRIDEi Q2NQS9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE75496 ; BAE75496 ; SG2221 .
    GeneIDi 3868805.
    KEGGi sgl:SG2221.
    PATRICi 23656379. VBISodGlo61428_5464.

    Phylogenomic databases

    eggNOGi COG0194.
    KOi K00942.
    OMAi MSHYNEY.
    OrthoDBi EOG6CP410.

    Enzyme and pathway databases

    BioCyci SGLO343509:GJJC-2297-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 3 hits.
    HAMAPi MF_00328. Guanylate_kinase.
    InterProi IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00625. Guanylate_kin. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host."
      Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S.
      Genome Res. 16:149-156(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: morsitans.

    Entry informationi

    Entry nameiKGUA_SODGM
    AccessioniPrimary (citable) accession number: Q2NQS9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3