Q2NQH2 (GLPE_SODGM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Thiosulfate sulfurtransferase glpE
EC=2.8.1.1

Gene names

Name:	glpE
Ordered Locus Names:	SG2328

Organism

Sodalis glossinidius (strain morsitans) [Complete proteome] [HAMAP]

Taxonomic identifier

343509 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Sodalis

Protein attributes

Sequence length	107 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide By similarity. HAMAP MF_01009
Catalytic activity	Thiosulfate + cyanide = sulfite + thiocyanate. HAMAP MF_01009
Subcellular location	Cytoplasm By similarity HAMAP MF_01009.
Sequence similarities	Belongs to the glpE family. Contains 1 rhodanese domain.

Ontologies

Keywords
Biological process	Glycerol metabolism
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	thiosulfate sulfurtransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 107	107	Thiosulfate sulfurtransferase glpE HAMAP MF_01009		PRO_1000062981
Regions
	Domain	17 – 105	89	Rhodanese
Sites
	Active site	65	1	Cysteine persulfide intermediate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2NQH2 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: D46888CF7D407A9F	FASTA	107	11,853
	10 20 30 40 50 60 MDQFATISME QARERWRQGE AVLVDIRDPQ SFAAGHLRGA FHLTNDTLPA FLAQHDLARP 70 80 90 100 VMVLCYHGNS SKGAAQYLLT QGVEVAYSVD GGFDAWLKAF PLETESL

References

[1]

"Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host." Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M., Aksoy S. Genome Res. 16:149-156(2006) [PubMed: 16365377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: morsitans.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008232 Genomic DNA. Translation: BAE75603.1.
RefSeq	YP_456008.1. NC_007712.1.
3D structure databases
HSSP	HSSP built from PDB template 2FSX based on UniProtKB P95198.
ProteinModelPortal	Q2NQH2.
SMR	Q2NQH2. Positions 1-103.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2NQH2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3867313.
GenomeReviews	Gene locus SG2328 in contig AP008232_GR.
KEGG	sgl:SG2328.
NMPDR	fig|343509.6.peg.5056.
PATRIC	23656749. VBISodGlo61428_5644.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0607.
HOGENOM	HBG743107.
OMA	FSAWHEA.
PhylomeDB	Q2NQH2.
Enzyme and pathway databases
BioCyc	SGLO343509:SG2328-MONOMER.
Family and domain databases
HAMAP	MF_01009. Thiosulf_sulfurtr. [Tree]
InterPro	IPR001763. Rhodanese-like. IPR023695. Thiosulf_sulfurTrfase. [Graphical view]
Gene3D	G3DSA:3.40.250.10. Rhodanese-like. 1 hit.
KO	K02439.
Pfam	PF00581. Rhodanese. 1 hit. [Graphical view]
SMART	SM00450. RHOD. 1 hit. [Graphical view]
SUPFAM	SSF52821. Rhodanese-like. 1 hit.
PROSITE	PS50206. RHODANESE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLPE_SODGM

Accession

Primary (citable) accession number: Q2NQH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program