Q2NL98 (VMAC_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Vimentin-type intermediate filament-associated coiled-coil protein

Gene names

Name:

VMAC

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Cytoplasm By similarity. Note: Colocalizes with vimentin-type intermediate filaments By similarity.

Ontologies

Keywords
Cellular component	Cytoplasm
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Vimentin-type intermediate filament-associated coiled-coil protein		PRO_0000319066
Regions
	Coiled coil	7 – 89	83	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q2NL98 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 9A3DF7957BC3D69A	FASTA	169	18,348
	10 20 30 40 50 60 MSAPPALQIR EANAHLAAVH RRAAELEARL DAAERTVHAQ AERLALHDQQ LRAALDELGR 70 80 90 100 110 120 AKDREIATLQ EQLMTSEATV HSLQATVHQR DELIRQLQPR AELLQDICRR RPPLAGLLDA 130 140 150 160 LAEAERLGPL PASDPGHPPP GGPGPPLDNS TGEEADRDHL QPAVFGTTV

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Thymus.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Cervix.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK124162 mRNA. Translation: BAG54017.1. BC110802 mRNA. Translation: AAI10803.1.
IPI	IPI00175793.
RefSeq	NP_001017921.1. NM_001017921.3.
UniGene	Hs.620821.
3D structure databases
ProteinModelPortal	Q2NL98.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q2NL98. 11 interactions.
PTM databases
PhosphoSite	Q2NL98.
Polymorphism databases
DMDM	121941615.
Proteomic databases
PaxDb	Q2NL98.
PRIDE	Q2NL98.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000339485; ENSP00000343348; ENSG00000187650.
GeneID	400673.
KEGG	hsa:400673.
UCSC	uc002mds.4. human.
Organism-specific databases
CTD	400673.
GeneCards	GC19P005855.
HGNC	HGNC:33803. VMAC.
neXtProt	NX_Q2NL98.
PharmGKB	PA165394584.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG40579.
HOGENOM	HOG000154823.
HOVERGEN	HBG097729.
InParanoid	Q2NL98.
OMA	ERTVRAQ.
OrthoDB	EOG4KH2WJ.
PhylomeDB	Q2NL98.
Gene expression databases
Bgee	Q2NL98.
Genevestigator	Q2NL98.
Family and domain databases
ProtoNet	Search...
Other
GenomeRNAi	400673.
NextBio	106099.
PMAP-CutDB	Q2NL98.

Entry information

Entry name

VMAC_HUMAN

Accession

Primary (citable) accession number: Q2NL98
Secondary accession number(s): B3KW55

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	February 7, 2006
Last modified:	April 3, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.