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Q2NL98

- VMAC_HUMAN

UniProt

Q2NL98 - VMAC_HUMAN

Protein

Vimentin-type intermediate filament-associated coiled-coil protein

Gene

VMAC

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Vimentin-type intermediate filament-associated coiled-coil protein
    Gene namesi
    Name:VMAC
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:33803. VMAC.

    Subcellular locationi

    Cytoplasm By similarity
    Note: Colocalizes with vimentin-type intermediate filaments.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA165394584.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 169169Vimentin-type intermediate filament-associated coiled-coil proteinPRO_0000319066Add
    BLAST

    Proteomic databases

    PaxDbiQ2NL98.
    PRIDEiQ2NL98.

    PTM databases

    PhosphoSiteiQ2NL98.

    Miscellaneous databases

    PMAP-CutDBQ2NL98.

    Expressioni

    Gene expression databases

    BgeeiQ2NL98.
    GenevestigatoriQ2NL98.

    Interactioni

    Protein-protein interaction databases

    BioGridi134697. 1 interaction.
    IntActiQ2NL98. 11 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2NL98.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili7 – 8983Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG40579.
    HOGENOMiHOG000154823.
    HOVERGENiHBG097729.
    InParanoidiQ2NL98.
    OMAiVQIREAN.
    OrthoDBiEOG7G1V94.
    PhylomeDBiQ2NL98.
    TreeFamiTF332566.

    Sequencei

    Sequence statusi: Complete.

    Q2NL98-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAPPALQIR EANAHLAAVH RRAAELEARL DAAERTVHAQ AERLALHDQQ    50
    LRAALDELGR AKDREIATLQ EQLMTSEATV HSLQATVHQR DELIRQLQPR 100
    AELLQDICRR RPPLAGLLDA LAEAERLGPL PASDPGHPPP GGPGPPLDNS 150
    TGEEADRDHL QPAVFGTTV 169
    Length:169
    Mass (Da):18,348
    Last modified:February 7, 2006 - v1
    Checksum:i9A3DF7957BC3D69A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK124162 mRNA. Translation: BAG54017.1.
    BC110802 mRNA. Translation: AAI10803.1.
    CCDSiCCDS32881.1.
    RefSeqiNP_001017921.1. NM_001017921.3.
    UniGeneiHs.620821.

    Genome annotation databases

    EnsembliENST00000339485; ENSP00000343348; ENSG00000187650.
    GeneIDi400673.
    KEGGihsa:400673.
    UCSCiuc002mds.4. human.

    Polymorphism databases

    DMDMi121941615.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK124162 mRNA. Translation: BAG54017.1 .
    BC110802 mRNA. Translation: AAI10803.1 .
    CCDSi CCDS32881.1.
    RefSeqi NP_001017921.1. NM_001017921.3.
    UniGenei Hs.620821.

    3D structure databases

    ProteinModelPortali Q2NL98.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 134697. 1 interaction.
    IntActi Q2NL98. 11 interactions.

    PTM databases

    PhosphoSitei Q2NL98.

    Polymorphism databases

    DMDMi 121941615.

    Proteomic databases

    PaxDbi Q2NL98.
    PRIDEi Q2NL98.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000339485 ; ENSP00000343348 ; ENSG00000187650 .
    GeneIDi 400673.
    KEGGi hsa:400673.
    UCSCi uc002mds.4. human.

    Organism-specific databases

    CTDi 400673.
    GeneCardsi GC19P005904.
    HGNCi HGNC:33803. VMAC.
    neXtProti NX_Q2NL98.
    PharmGKBi PA165394584.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG40579.
    HOGENOMi HOG000154823.
    HOVERGENi HBG097729.
    InParanoidi Q2NL98.
    OMAi VQIREAN.
    OrthoDBi EOG7G1V94.
    PhylomeDBi Q2NL98.
    TreeFami TF332566.

    Miscellaneous databases

    GenomeRNAii 400673.
    NextBioi 106099.
    PMAP-CutDB Q2NL98.
    PROi Q2NL98.

    Gene expression databases

    Bgeei Q2NL98.
    Genevestigatori Q2NL98.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Thymus.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Cervix.

    Entry informationi

    Entry nameiVMAC_HUMAN
    AccessioniPrimary (citable) accession number: Q2NL98
    Secondary accession number(s): B3KW55
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM

    External Data

    Dasty 3