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Protein

COX assembly mitochondrial protein 2 homolog

Gene

CMC2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in cytochrome c oxidase biogenesis.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
COX assembly mitochondrial protein 2 homolog
Gene namesi
Name:CMC2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componentsi: Chromosome 18, Chromosome 7

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003650871 – 79COX assembly mitochondrial protein 2 homologAdd BLAST79

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi14 ↔ 47PROSITE-ProRule annotation
Disulfide bondi24 ↔ 37PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ2NKR3.

Expressioni

Gene expression databases

BgeeiENSBTAG00000017009.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052197.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 55CHCHPROSITE-ProRule annotationAdd BLAST45

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi14 – 24Cx9C motif 1PROSITE-ProRule annotationAdd BLAST11
Motifi37 – 47Cx9C motif 2PROSITE-ProRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the CMC family.Curated
Contains 1 CHCH (coiled coil-helix-coiled coil-helix) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ2NKR3.
KOiK18172.
OMAiCHKEHSV.
OrthoDBiEOG091G17A1.
TreeFamiTF314049.

Family and domain databases

InterProiIPR013892. Cyt_c_biogenesis_Cmc1-like.
[Graphical view]
PfamiPF08583. Cmc1. 1 hit.
[Graphical view]
PROSITEiPS51808. CHCH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2NKR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDLSPHLH TEECNVLINL LKECHKNHSI LKFFGHCNDL DREMRKCLKN
60 70
EYMEKRNKSR ELGNAMRKRL FNPPEESEN
Length:79
Mass (Da):9,489
Last modified:February 7, 2006 - v1
Checksum:i7CB77A62F3D86262
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111685 mRNA. Translation: AAI11686.1.
RefSeqiNP_001106646.1. NM_001113175.2.
XP_010796373.1. XM_010798071.1.
XP_010805885.1. XM_010807583.1.
UniGeneiBt.42944.

Genome annotation databases

EnsembliENSBTAT00000022619; ENSBTAP00000022619; ENSBTAG00000017009.
ENSBTAT00000032574; ENSBTAP00000052197; ENSBTAG00000030274.
GeneIDi101905951.
614078.
KEGGibta:101905951.
bta:614078.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111685 mRNA. Translation: AAI11686.1.
RefSeqiNP_001106646.1. NM_001113175.2.
XP_010796373.1. XM_010798071.1.
XP_010805885.1. XM_010807583.1.
UniGeneiBt.42944.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052197.

Proteomic databases

PaxDbiQ2NKR3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000022619; ENSBTAP00000022619; ENSBTAG00000017009.
ENSBTAT00000032574; ENSBTAP00000052197; ENSBTAG00000030274.
GeneIDi101905951.
614078.
KEGGibta:101905951.
bta:614078.

Organism-specific databases

CTDi56942.

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ2NKR3.
KOiK18172.
OMAiCHKEHSV.
OrthoDBiEOG091G17A1.
TreeFamiTF314049.

Gene expression databases

BgeeiENSBTAG00000017009.

Family and domain databases

InterProiIPR013892. Cyt_c_biogenesis_Cmc1-like.
[Graphical view]
PfamiPF08583. Cmc1. 1 hit.
[Graphical view]
PROSITEiPS51808. CHCH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCOXM2_BOVIN
AccessioniPrimary (citable) accession number: Q2NKR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: February 7, 2006
Last modified: November 2, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.