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Protein

COX assembly mitochondrial protein 2 homolog

Gene

CMC2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in cytochrome c oxidase biogenesis.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
COX assembly mitochondrial protein 2 homolog
Gene namesi
Name:CMC2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componentsi: Chromosome 18, Chromosome 7

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003650871 – 79COX assembly mitochondrial protein 2 homologAdd BLAST79

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi14 ↔ 47PROSITE-ProRule annotation
Disulfide bondi24 ↔ 37PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ2NKR3.

Expressioni

Gene expression databases

BgeeiENSBTAG00000017009.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052197.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 55CHCHPROSITE-ProRule annotationAdd BLAST45

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi14 – 24Cx9C motif 1PROSITE-ProRule annotationAdd BLAST11
Motifi37 – 47Cx9C motif 2PROSITE-ProRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the CMC family.Curated

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ2NKR3.
KOiK18172.
OMAiCHKEHSV.
OrthoDBiEOG09020F1Q.
TreeFamiTF314049.

Family and domain databases

InterProiView protein in InterPro
IPR013892. Cyt_c_biogenesis_Cmc1-like.
PfamiView protein in Pfam
PF08583. Cmc1. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NKR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHPDLSPHLH TEECNVLINL LKECHKNHSI LKFFGHCNDL DREMRKCLKN
60 70
EYMEKRNKSR ELGNAMRKRL FNPPEESEN
Length:79
Mass (Da):9,489
Last modified:February 7, 2006 - v1
Checksum:i7CB77A62F3D86262
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111685 mRNA. Translation: AAI11686.1.
RefSeqiNP_001106646.1. NM_001113175.2.
XP_010796373.1. XM_010798071.1.
XP_010805885.1. XM_010807583.1.
UniGeneiBt.42944.

Genome annotation databases

EnsembliENSBTAT00000022619; ENSBTAP00000022619; ENSBTAG00000017009.
ENSBTAT00000032574; ENSBTAP00000052197; ENSBTAG00000030274.
GeneIDi101905951.
614078.
KEGGibta:101905951.
bta:614078.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC111685 mRNA. Translation: AAI11686.1.
RefSeqiNP_001106646.1. NM_001113175.2.
XP_010796373.1. XM_010798071.1.
XP_010805885.1. XM_010807583.1.
UniGeneiBt.42944.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000052197.

Proteomic databases

PaxDbiQ2NKR3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000022619; ENSBTAP00000022619; ENSBTAG00000017009.
ENSBTAT00000032574; ENSBTAP00000052197; ENSBTAG00000030274.
GeneIDi101905951.
614078.
KEGGibta:101905951.
bta:614078.

Organism-specific databases

CTDi56942.

Phylogenomic databases

eggNOGiKOG4148. Eukaryota.
ENOG41123JB. LUCA.
GeneTreeiENSGT00390000016908.
HOGENOMiHOG000212591.
HOVERGENiHBG045487.
InParanoidiQ2NKR3.
KOiK18172.
OMAiCHKEHSV.
OrthoDBiEOG09020F1Q.
TreeFamiTF314049.

Gene expression databases

BgeeiENSBTAG00000017009.

Family and domain databases

InterProiView protein in InterPro
IPR013892. Cyt_c_biogenesis_Cmc1-like.
PfamiView protein in Pfam
PF08583. Cmc1. 1 hit.
PROSITEiView protein in PROSITE
PS51808. CHCH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOXM2_BOVIN
AccessioniPrimary (citable) accession number: Q2NKR3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: February 7, 2006
Last modified: February 15, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.