ID   G6PI_AYWBP              Reviewed;         426 AA.
AC   Q2NJ38;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Glucose-6-phosphate isomerase;
DE            Short=GPI;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase;
DE            Short=PGI;
DE   AltName: Full=Phosphohexose isomerase;
DE            Short=PHI;
GN   Name=pgi; OrderedLocusNames=AYWB_438;
OS   Aster yellows witches'-broom phytoplasma (strain AYWB).
OC   Bacteria; Tenericutes; Mollicutes; Acholeplasmatales;
OC   Acholeplasmataceae; Candidatus Phytoplasma;
OC   Candidatus Phytoplasma asteris.
OX   NCBI_TaxID=322098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16672622; DOI=10.1128/JB.188.10.3682-3696.2006;
RA   Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A.,
RA   Shevchenko D.V., Tsukerman K., Walunas T., Lapidus A., Campbell J.W.,
RA   Hogenhout S.A.;
RT   "Living with genome instability: the adaptation of phytoplasmas to
RT   diverse environments of their insect and plant hosts.";
RL   J. Bacteriol. 188:3682-3696(2006).
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   EMBL; CP000061; ABC65555.1; -; Genomic_DNA.
DR   RefSeq; YP_456634.1; -.
DR   GeneID; 3865771; -.
DR   GenomeReviews; CP000061_GR; AYWB_438.
DR   KEGG; ayw:AYWB_438; -.
DR   HOGENOM; Q2NJ38; -.
DR   OMA; Q2NJ38; DQPGVEG.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00473; -; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; G6P_Isomerase; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase.
FT   CHAIN         1    426       Glucose-6-phosphate isomerase.
FT                                /FTId=PRO_0000252608.
FT   ACT_SITE    282    282       Proton donor (By similarity).
FT   ACT_SITE    303    303       By similarity.
FT   ACT_SITE    417    417       By similarity.
SQ   SEQUENCE   426 AA;  48652 MW;  78CA0E8CB7D8F3D0 CRC64;
     MLKLNLEGIY NFLDWRKHTQ TYAPQIKSIH QKLHQDKQLK EKYLGWLELP LHFDFKEIEK
     MKQLKNFHPN LDVLVVIGIG GSYLGAKAGI EFLQTPFKKT KPEILFAGHQ VSGNYLTNLL
     HFLKNKNWAI NVISKSGTTL EPALAFRILK KEIEEKYGKQ LAKNRIFVTT DSQKGVLLNL
     ALKEGYQTFV IPDSVGGRFS VFTSVGILPF VFANLDVASM MKGALQSYHD TFQEDLLQNQ
     AYKYALARYL FHTQQNKKME ILVSYEPNLL SFSEWWKQLF AESEGKEEKG LFVGATNNST
     DLHSLGQFIQ EGTKMLFETV LNVSSIKDDC VVPHILNELD NLNYVAGKTY SQINQKILQA
     TRQAHIEGKV PNLEIVIPTL DAYHFGYLAY FFQKACAMSG LLLGINPFNQ HGVEIYKQKM
     FALLKP
//