Reviewed, UniProtKB/Swiss-Prot Q2NJ38 (G6PI_AYWBP)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase
      Short name=GPI
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase
      Short name=PGI
    Phosphohexose isomerase
      Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	AYWB_438

Organism

Aster yellows witches'-broom phytoplasma (strain AYWB) [Complete proteome] [HAMAP]

Taxonomic identifier

322098 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Candidatus Phytoplasma › Candidatus Phytoplasma asteris

Protein attributes

Sequence length	426 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 426	426	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_0000252608
Sites
	Active site	282	1	Proton donor By similarity
	Active site	303	1	By similarity
	Active site	417	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2NJ38-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 78CA0E8CB7D8F3D0	FASTA	426	48,652
	10 20 30 40 50 60 MLKLNLEGIY NFLDWRKHTQ TYAPQIKSIH QKLHQDKQLK EKYLGWLELP LHFDFKEIEK 70 80 90 100 110 120 MKQLKNFHPN LDVLVVIGIG GSYLGAKAGI EFLQTPFKKT KPEILFAGHQ VSGNYLTNLL 130 140 150 160 170 180 HFLKNKNWAI NVISKSGTTL EPALAFRILK KEIEEKYGKQ LAKNRIFVTT DSQKGVLLNL 190 200 210 220 230 240 ALKEGYQTFV IPDSVGGRFS VFTSVGILPF VFANLDVASM MKGALQSYHD TFQEDLLQNQ 250 260 270 280 290 300 AYKYALARYL FHTQQNKKME ILVSYEPNLL SFSEWWKQLF AESEGKEEKG LFVGATNNST 310 320 330 340 350 360 DLHSLGQFIQ EGTKMLFETV LNVSSIKDDC VVPHILNELD NLNYVAGKTY SQINQKILQA 370 380 390 400 410 420 TRQAHIEGKV PNLEIVIPTL DAYHFGYLAY FFQKACAMSG LLLGINPFNQ HGVEIYKQKM FALLKP

References

[1]

"Living with genome instability: the adaptation of phytoplasmas to diverse environments of their insect and plant hosts." Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A., Shevchenko D.V., Tsukerman K., Walunas T., Lapidus A., Campbell J.W., Hogenhout S.A. J. Bacteriol. 188:3682-3696(2006) [PubMed: 16672622] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000061 Genomic DNA. Translation: ABC65555.1.
RefSeq	YP_456634.1.
3D structure databases
SMR	Q2NJ38. Positions 2-425.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2NJ38.
Genome annotation databases
GeneID	3865771.
GenomeReviews	Gene locus AYWB_438 in contig CP000061_GR.
KEGG	ayw:AYWB_438.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0166.
HOGENOM	HBG615843.
OMA	STHFIVI.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_AYWBP

Accession

Primary (citable) accession number: Q2NJ38

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	February 7, 2006
Last modified:	January 19, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)