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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Aster yellows witches'-broom phytoplasma (strain AYWB)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi498MagnesiumUniRule annotation1
Metal bindingi504MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, RNA-binding, Transferase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciAYEL322098:G1G4I-478-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:AYWB_470
OrganismiAster yellows witches'-broom phytoplasma (strain AYWB)
Taxonomic identifieri322098 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus PhytoplasmaCandidatus Phytoplasma asteris
Proteomesi
  • UP000001934 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003295061 – 715Polyribonucleotide nucleotidyltransferaseAdd BLAST715

Interactioni

Protein-protein interaction databases

STRINGi322098.AYWB_470

Structurei

3D structure databases

ProteinModelPortaliQ2NJ06
SMRiQ2NJ06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini565 – 625KHUniRule annotationAdd BLAST61
Domaini635 – 709S1 motifUniRule annotationAdd BLAST75

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QUF Bacteria
COG1185 LUCA
HOGENOMiHOG000218326
KOiK00962
OMAiRYMHNYN
OrthoDBiPOG091H00M0

Family and domain databases

Gene3Di3.30.230.70, 2 hits
HAMAPiMF_01595 PNPase, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR015847 ExoRNase_PH_dom2
IPR036345 ExoRNase_PH_dom2_sf
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR012340 NA-bd_OB-fold
IPR012162 PNPase
IPR027408 PNPase/RNase_PH_dom_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR022967 S1_dom
IPR003029 S1_domain
PANTHERiPTHR11252 PTHR11252, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF01138 RNase_PH, 2 hits
PF03725 RNase_PH_C, 1 hit
PIRSFiPIRSF005499 PNPase, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00316 S1, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF54211 SSF54211, 2 hits
SSF54791 SSF54791, 1 hit
SSF55666 SSF55666, 2 hits
TIGRFAMsiTIGR03591 polynuc_phos, 1 hit
PROSITEiView protein in PROSITE
PS50084 KH_TYPE_1, 1 hit
PS50126 S1, 1 hit

Sequencei

Sequence statusi: Complete.

Q2NJ06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKVFETTN LKDSFQVEIG TYARNVDSSI LVRYQDTVVL TTMVFSRKPN
60 70 80 90 100
NLDFLPLTVI YQEKLYAAGK IPGSFLRREG RSNDHEILTS RLIDRSLRPL
110 120 130 140 150
FPDYFQQEVQ VINTVLSLDP DFKSELASML GSSLSLLISE IPFFEAISGV
160 170 180 190 200
YVGKINNEFI INPTLQQLAN STLHLIVAGT KHNVTMIEAH ANEVSEQDFL
210 220 230 240 250
EAINFAHQYI KKLCLFQENI KQQFAPVKMT KTLHQTEQIQ QQSFFAKNHS
260 270 280 290 300
QVKQAILSCN SKNDLQQLKE QILDQAKQTP FFKTIDAITV FDYEAHKKHL
310 320 330 340 350
QITENLFQKL SKQEMRSLIL QEKIRPDKRE LEEIRTLESQ IDLLPRAHGS
360 370 380 390 400
ALFTRGKTQS LAAVTLGCLS ESKIIDGLSD EQNKRFMLHY NFPPFSVGAV
410 420 430 440 450
GRYTAPSRRE IGHGTLAEKA ISQVLPEEKD FPYTIRVVSE ILESNGSSSQ
460 470 480 490 500
ATVCSSSLAL MASGVPLKKA VAGISVGLVF DQETNKYVIL SDIQGLEDHV
510 520 530 540 550
GDMDLKIAGT NKGITALQMD LKIQGIPFKI LQEAFLQAKK GRLHILEQMN
560 570 580 590 600
QTISQPRLEV SKYAPKVCMM QIKPEKIRDI IGSGGKIINQ IIESHDGVKI
610 620 630 640 650
DIEQDGRVFV MHSNLETVKK TVAFIESLIQ EIQVGTCYQA SILRFLSDKQ
660 670 680 690 700
GKMIGAVAQV CPGIEGLIHV NKMKFQKITD VLKIGETVLV KCTKINERGR
710
IDFLLLPKKT QEKNS
Length:715
Mass (Da):80,440
Last modified:February 7, 2006 - v1
Checksum:i462807B60999C430
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000061 Genomic DNA Translation: ABC65587.1
RefSeqiWP_011412751.1, NC_007716.1

Genome annotation databases

EnsemblBacteriaiABC65587; ABC65587; AYWB_470
KEGGiayw:AYWB_470

Similar proteinsi

Entry informationi

Entry nameiPNP_AYWBP
AccessioniPrimary (citable) accession number: Q2NJ06
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: February 7, 2006
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health