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Q2NJ06

- PNP_AYWBP

UniProt

Q2NJ06 - PNP_AYWBP

Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Aster yellows witches'-broom phytoplasma (strain AYWB)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (07 Feb 2006)
      Previous versions | rss
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    • Comment

    Functioni

    Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

    Catalytic activityi

    RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi498 – 4981MagnesiumUniRule annotation
    Metal bindingi504 – 5041MagnesiumUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
    3. RNA binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    Magnesium, Metal-binding, RNA-binding

    Enzyme and pathway databases

    BioCyciCPHY322098:GJ7E-494-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
    Alternative name(s):
    Polynucleotide phosphorylaseUniRule annotation
    Short name:
    PNPaseUniRule annotation
    Gene namesi
    Name:pnpUniRule annotation
    Ordered Locus Names:AYWB_470
    OrganismiAster yellows witches'-broom phytoplasma (strain AYWB)
    Taxonomic identifieri322098 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus PhytoplasmaCandidatus Phytoplasma asteris
    ProteomesiUP000001934: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 715715Polyribonucleotide nucleotidyltransferasePRO_0000329506Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi322098.AYWB_470.

    Structurei

    3D structure databases

    ProteinModelPortaliQ2NJ06.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini565 – 62561KHUniRule annotationAdd
    BLAST
    Domaini635 – 70975S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
    Contains 1 KH domain.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1185.
    HOGENOMiHOG000218326.
    KOiK00962.
    OMAiPRWDWVA.
    OrthoDBiEOG6WT8CC.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPiMF_01595. PNPase.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view]
    PANTHERiPTHR11252. PTHR11252. 1 hit.
    PfamiPF00013. KH_1. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    [Graphical view]
    PIRSFiPIRSF005499. PNPase. 1 hit.
    SMARTiSM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
    PROSITEiPS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q2NJ06-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLKKVFETTN LKDSFQVEIG TYARNVDSSI LVRYQDTVVL TTMVFSRKPN    50
    NLDFLPLTVI YQEKLYAAGK IPGSFLRREG RSNDHEILTS RLIDRSLRPL 100
    FPDYFQQEVQ VINTVLSLDP DFKSELASML GSSLSLLISE IPFFEAISGV 150
    YVGKINNEFI INPTLQQLAN STLHLIVAGT KHNVTMIEAH ANEVSEQDFL 200
    EAINFAHQYI KKLCLFQENI KQQFAPVKMT KTLHQTEQIQ QQSFFAKNHS 250
    QVKQAILSCN SKNDLQQLKE QILDQAKQTP FFKTIDAITV FDYEAHKKHL 300
    QITENLFQKL SKQEMRSLIL QEKIRPDKRE LEEIRTLESQ IDLLPRAHGS 350
    ALFTRGKTQS LAAVTLGCLS ESKIIDGLSD EQNKRFMLHY NFPPFSVGAV 400
    GRYTAPSRRE IGHGTLAEKA ISQVLPEEKD FPYTIRVVSE ILESNGSSSQ 450
    ATVCSSSLAL MASGVPLKKA VAGISVGLVF DQETNKYVIL SDIQGLEDHV 500
    GDMDLKIAGT NKGITALQMD LKIQGIPFKI LQEAFLQAKK GRLHILEQMN 550
    QTISQPRLEV SKYAPKVCMM QIKPEKIRDI IGSGGKIINQ IIESHDGVKI 600
    DIEQDGRVFV MHSNLETVKK TVAFIESLIQ EIQVGTCYQA SILRFLSDKQ 650
    GKMIGAVAQV CPGIEGLIHV NKMKFQKITD VLKIGETVLV KCTKINERGR 700
    IDFLLLPKKT QEKNS 715
    Length:715
    Mass (Da):80,440
    Last modified:February 7, 2006 - v1
    Checksum:i462807B60999C430
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000061 Genomic DNA. Translation: ABC65587.1.
    RefSeqiWP_011412751.1. NC_007716.1.
    YP_456666.1. NC_007716.1.

    Genome annotation databases

    EnsemblBacteriaiABC65587; ABC65587; AYWB_470.
    GeneIDi3865843.
    KEGGiayw:AYWB_470.
    PATRICi21004976. VBIAstYel136969_0529.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000061 Genomic DNA. Translation: ABC65587.1 .
    RefSeqi WP_011412751.1. NC_007716.1.
    YP_456666.1. NC_007716.1.

    3D structure databases

    ProteinModelPortali Q2NJ06.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 322098.AYWB_470.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABC65587 ; ABC65587 ; AYWB_470 .
    GeneIDi 3865843.
    KEGGi ayw:AYWB_470.
    PATRICi 21004976. VBIAstYel136969_0529.

    Phylogenomic databases

    eggNOGi COG1185.
    HOGENOMi HOG000218326.
    KOi K00962.
    OMAi PRWDWVA.
    OrthoDBi EOG6WT8CC.

    Enzyme and pathway databases

    BioCyci CPHY322098:GJ7E-494-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.30.1370.10. 1 hit.
    3.30.230.70. 2 hits.
    HAMAPi MF_01595. PNPase.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR004087. KH_dom.
    IPR004088. KH_dom_type_1.
    IPR012340. NA-bd_OB-fold.
    IPR012162. PNPase.
    IPR027408. PNPase/RNase_PH_dom.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR022967. RNA-binding_domain_S1.
    [Graphical view ]
    PANTHERi PTHR11252. PTHR11252. 1 hit.
    Pfami PF00013. KH_1. 1 hit.
    PF01138. RNase_PH. 2 hits.
    PF03725. RNase_PH_C. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF005499. PNPase. 1 hit.
    SMARTi SM00322. KH. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF54211. SSF54211. 2 hits.
    SSF54791. SSF54791. 1 hit.
    SSF55666. SSF55666. 2 hits.
    TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
    PROSITEi PS50084. KH_TYPE_1. 1 hit.
    PS50126. S1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Living with genome instability: the adaptation of phytoplasmas to diverse environments of their insect and plant hosts."
      Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A., Shevchenko D.V., Tsukerman K., Walunas T., Lapidus A., Campbell J.W., Hogenhout S.A.
      J. Bacteriol. 188:3682-3696(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AYWB.

    Entry informationi

    Entry nameiPNP_AYWBP
    AccessioniPrimary (citable) accession number: Q2NJ06
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: February 7, 2006
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3