Q2NIZ4 (KCY_AYWBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	AYWB_482

Organism

Aster yellows witches'-broom phytoplasma (strain AYWB) [Complete proteome] [HAMAP]

Taxonomic identifier

322098 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Candidatus Phytoplasma › Candidatus Phytoplasma asteris

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Cytidylate kinase HAMAP MF_00238		PRO_1000048181
Regions
	Nucleotide binding	12 – 20	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q2NIZ4 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 0ECC31AB6A0EBF11	FASTA	223	25,208
	10 20 30 40 50 60 MHMRSFKIAI DGPAGSGKST ISKKLSQKLG WNHIDTGAMF RALTLYLLEN EVSWHNEKSL 70 80 90 100 110 120 NQILDKINLS YSCNKIFLNQ EDVSLKIKSL DVEKHVSSVA LIPGVRTKLL KLQKEICANT 130 140 150 160 170 180 PNLIMDGRDI GTVVMPDANL KIFLTANITK RALRKQQEDA QNGKITDITQ IMKQLKERDH 190 200 210 220 KDYHRHLAPL SKALDAILLD TTELSIDELI AKITTLIEKK RRA

References

[1]

"Living with genome instability: the adaptation of phytoplasmas to diverse environments of their insect and plant hosts." Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A., Shevchenko D.V., Tsukerman K., Walunas T., Lapidus A., Campbell J.W., Hogenhout S.A. J. Bacteriol. 188:3682-3696(2006) [PubMed: 16672622] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AYWB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000061 Genomic DNA. Translation: ABC65599.1.
RefSeq	YP_456678.1. NC_007716.1.
3D structure databases
ProteinModelPortal	Q2NIZ4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2NIZ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3865863.
GenomeReviews	Gene locus AYWB_482 in contig CP000061_GR.
KEGG	ayw:AYWB_482.
PATRIC	21005016. VBIAstYel136969_0541.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0283.
HOGENOM	HBG354377.
OMA	DIGTVIC.
PhylomeDB	Q2NIZ4.
ProtClustDB	CLSK343693.
Enzyme and pathway databases
BioCyc	AYEL322098:AYWB_482-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR000850. Adenylate_kin. IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF00406. ADK. 1 hit. PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_AYWBP

Accession

Primary (citable) accession number: Q2NIZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program