Q2NIR6 (ACKA_AYWBP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	AYWB_560

Organism

Aster yellows witches'-broom phytoplasma (strain AYWB) [Complete proteome] [HAMAP]

Taxonomic identifier

322098 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Acholeplasmatales › Acholeplasmataceae › Candidatus Phytoplasma › Candidatus Phytoplasma asteris

Protein attributes

Sequence length	410 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 410	410	Acetate kinase HAMAP MF_00020		PRO_1000002207

Sequences

	Sequence		Length	Mass (Da)
	Q2NIR6 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 01B4B1C42546D2BE	FASTA	410	45,428
	10 20 30 40 50 60 MKIMSVNSGS SSLKFQLLEM PQQEVIVSVL FERIGSNQAV LTMKTKDKKD KQVLEVPNHQ 70 80 90 100 110 120 TAVELLLDAL IQKKVINALE EIEGVGHRVV QGGEIFSDSA VLTEKTLAQI ESLCDLAPLH 130 140 150 160 170 180 NPANIISIKA FQKVLPQTFQ VAVFDTTFHQ SMPAVNFLYA TPYYWYQKYQ IRKYGAHGTS 190 200 210 220 230 240 YKYVTEQMQQ ILAKDNAKII ICHAGNGVSL CAVDSGKSVD TSMGFTPLEG VPMGTRSGNI 250 260 270 280 290 300 DPAVVKFISE KENKTVACVI DDLNKKSGYL GVSGISNDTR DILASIKEGN QQAILSHDIQ 310 320 330 340 350 360 VKRIVDYIAS YYVLLKGIDA LVFTAGIGEN SSFFRSEIIK RLSVLGIKLD EEKNKVKGKQ 370 380 390 400 410 ELITTPDSTI KAFVIPTNEE LAIAQDVLRL KQNKTNQYKD DQQECFCFCG

References

[1]

"Living with genome instability: the adaptation of phytoplasmas to diverse environments of their insect and plant hosts." Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A., Shevchenko D.V., Tsukerman K., Walunas T., Lapidus A., Campbell J.W., Hogenhout S.A. J. Bacteriol. 188:3682-3696(2006) [PubMed: 16672622] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AYWB.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000061 Genomic DNA. Translation: ABC65677.1.
RefSeq	YP_456756.1. NC_007716.1.
3D structure databases
ProteinModelPortal	Q2NIR6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2NIR6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3866053.
GenomeReviews	Gene locus AYWB_560 in contig CP000061_GR.
KEGG	ayw:AYWB_560.
PATRIC	21005184. VBIAstYel136969_0620.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0282.
HOGENOM	HBG285863.
OMA	LIDMTNE.
PhylomeDB	Q2NIR6.
ProtClustDB	PRK00180.
Enzyme and pathway databases
BioCyc	AYEL322098:AYWB_560-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_AYWBP

Accession

Primary (citable) accession number: Q2NIR6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program