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Protein

Guanylate kinase

Gene

gmk

Organism
Aster yellows witches'-broom phytoplasma (strain AYWB)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:AYWB_655
OrganismiAster yellows witches'-broom phytoplasma (strain AYWB)
Taxonomic identifieri322098 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesAcholeplasmatalesAcholeplasmataceaeCandidatus PhytoplasmaCandidatus Phytoplasma asteris
Proteomesi
  • UP000001934 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002662861 – 211Guanylate kinaseAdd BLAST211

Interactioni

Protein-protein interaction databases

STRINGi322098.AYWB_655.

Structurei

3D structure databases

ProteinModelPortaliQ2NIH1.
SMRiQ2NIH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 187Guanylate kinase-likeUniRule annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA. Bacteria.
COG0194. LUCA.
HOGENOMiHOG000037639.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NIH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNKKGLLI ILSGPSGVGK ATVRKALFEM TNHNFVYSVS ATTRKPRPGE
60 70 80 90 100
QDGKDYHFLT KEEFEKGIEN NCFLEWAKFI DHYYGTPKKQ IQDFLKQGKE
110 120 130 140 150
VFLEIEVEGA THLRKKRMPN TVFIFLVPPK KKDLYDRLKK RGTEQEINIV
160 170 180 190 200
QRIAKANNEF RLAHKYDYIV VNDEVANAAD RIIAIIRAEH AKTKRSIRNY
210
LKILEDNVYA E
Length:211
Mass (Da):24,544
Last modified:February 7, 2006 - v1
Checksum:i86D88145AEAA04BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000061 Genomic DNA. Translation: ABC65772.1.
RefSeqiWP_011412933.1. NC_007716.1.

Genome annotation databases

EnsemblBacteriaiABC65772; ABC65772; AYWB_655.
KEGGiayw:AYWB_655.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiKGUA_AYWBP
AccessioniPrimary (citable) accession number: Q2NIH1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: February 7, 2006
Last modified: June 7, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families