Q2NI71 (Q2NI71_METST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Name:	purM EMBL ABC56690.1
Ordered Locus Names:	Msp_0280

Organism

Methanosphaera stadtmanae (strain DSM 3091) [Complete proteome] [HAMAP]

Taxonomic identifier

339860 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanosphaera

Protein attributes

Sequence length	342 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL ABC56690.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2NI71 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 6A57FD4F83FCA51F	FASTA	342	36,968
	10 20 30 40 50 60 MVTYSEAGVD ISLEEQTVRA LTGELSETLD YRNIIKNKGH FAALVDFGSR AIAMSTDGVG 70 80 90 100 110 120 SKILIANLMN KFDTVGIDCI AMVVNDILCV GAEPIAMVDY LAVEHPDPEV ASQIGKGLKV 130 140 150 160 170 180 GCQQAKIAMI GGETASLPKI IKDFDLAGTG IGTVDKEDII TGTQIKDGDI IIGIESSGVH 190 200 210 220 230 240 SNGLSLARKA LLEIANFNVD DKLPTDNSTT VGEALLEPTI IYVDAIMDLL NSDIEVHGLG 250 260 270 280 290 300 HITGGGFSNL KRLNHDMTYI INNLPETLPI FKAIQATGIE DKEMYHVFNM GIGFAVILDG 310 320 330 340 KYQDEALEIL NKYHKSYVIG EIKEDSDNRV LITTNENKKI EL

References

[1]

"The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis." Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R., Gottschalk G., Thauer R.K. J. Bacteriol. 188:642-658(2006) [PubMed: 16385054] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000102 Genomic DNA. Translation: ABC56690.1.
RefSeq	YP_447333.1. NC_007681.1.
3D structure databases
ProteinModelPortal	Q2NI71.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2NI71.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3855428.
GenomeReviews	Gene locus Msp_0280 in contig CP000102_GR.
KEGG	mst:Msp_0280.
NMPDR	fig|339860.6.peg.271.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04189.
HOGENOM	HBG531222.
OMA	GIDMIAM.
PhylomeDB	Q2NI71.
ProtClustDB	PRK05385.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q2NI71_METST

Accession

Primary (citable) accession number: Q2NI71

Entry history

Integrated into UniProtKB/TrEMBL:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)