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Protein

TATA-box-binding protein

Gene

tbp

Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-box-binding proteinUniRule annotation
Alternative name(s):
Box A-binding proteinUniRule annotation
Short name:
BAPUniRule annotation
TATA sequence-binding proteinUniRule annotation
Short name:
TBPUniRule annotation
TATA-box factorUniRule annotation
Gene namesi
Name:tbpUniRule annotation
Ordered Locus Names:Msp_1097
OrganismiMethanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Taxonomic identifieri339860 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanosphaera
Proteomesi
  • UP000001931 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000498821 – 183TATA-box-binding proteinAdd BLAST183

Interactioni

Protein-protein interaction databases

STRINGi339860.Msp_1097.

Structurei

3D structure databases

ProteinModelPortaliQ2NFC3.
SMRiQ2NFC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati8 – 841Add BLAST77
Repeati99 – 1752Add BLAST77

Sequence similaritiesi

Belongs to the TBP family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
KOiK03120.
OMAiMESTINI.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q2NFC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDVEIKVEN IVASATLGKS LELPKIAPAL ENVEYNLEQF PGLVFKLKDP
60 70 80 90 100
KTAALIFGSG KLVCTGAKCI EDSIKAIHMT VDKIRELDTE IPEEFEIKIQ
110 120 130 140 150
NIVASANLGK VLNLEAVALD LENTEYEPEQ FPGLVYRLSD PKVVLLLFGS
160 170 180
GKVVCTGAKT ADQALLGVQK TKERLIELYL IEE
Length:183
Mass (Da):20,058
Last modified:February 7, 2006 - v1
Checksum:i756E1C4E8C8772EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000102 Genomic DNA. Translation: ABC57480.1.
RefSeqiWP_011406679.1. NC_007681.1.

Genome annotation databases

EnsemblBacteriaiABC57480; ABC57480; Msp_1097.
GeneIDi3856088.
KEGGimst:Msp_1097.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000102 Genomic DNA. Translation: ABC57480.1.
RefSeqiWP_011406679.1. NC_007681.1.

3D structure databases

ProteinModelPortaliQ2NFC3.
SMRiQ2NFC3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi339860.Msp_1097.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC57480; ABC57480; Msp_1097.
GeneIDi3856088.
KEGGimst:Msp_1097.

Phylogenomic databases

eggNOGiarCOG01764. Archaea.
COG2101. LUCA.
HOGENOMiHOG000105163.
KOiK03120.
OMAiMESTINI.

Family and domain databases

CDDicd04518. TBP_archaea. 1 hit.
Gene3Di3.30.310.10. 2 hits.
HAMAPiMF_00408. TATA_bind_prot_arch. 1 hit.
InterProiIPR012295. Beta2_adaptin/TBP_C_dom.
IPR000814. TBP.
IPR033711. TBP_archaea.
IPR030491. TBP_CS.
[Graphical view]
PANTHERiPTHR10126. PTHR10126. 1 hit.
PfamiPF00352. TBP. 2 hits.
[Graphical view]
PRINTSiPR00686. TIFACTORIID.
PROSITEiPS00351. TFIID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBP_METST
AccessioniPrimary (citable) accession number: Q2NFC3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 7, 2006
Last modified: November 2, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.