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Q2NF93 (Q2NF93_METST) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
5,10-methylenetetrahydromethanopterin reductase HAMAP MF_01091
EC=1.5.99.11 HAMAP MF_01091
Alternative name(s):
Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase HAMAP MF_01091
Methylene-H(4)MPT reductase HAMAP MF_01091
Gene names
Name:mer HAMAP MF_01091 EMBL ABC57510.1
Ordered Locus Names:Msp_1128
OrganismMethanosphaera stadtmanae (strain DSM 3091) [Complete proteome] [HAMAP]
Taxonomic identifier339860 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanosphaera

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidation of methyl-H4MPT to methylene-H4MPT By similarity. HAMAP MF_01091

Catalytic activity

5-methyltetrahydromethanopterin + coenzyme F420 = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. HAMAP MF_01091

Subcellular location

Cytoplasm By similarity HAMAP MF_01091.

Sequence similarities

Belongs to the mer family. HAMAP MF_01091

Sequences

Sequence LengthMass (Da)Tools
Q2NF93 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 2B345A6CD0754EBC

FASTA32235,010
        10         20         30         40         50         60 
MKFSLELLPN EPIKDILELI KLAENIGFEN VWITDHYNNR DVFEVLSIAA YETSTIKMGS 

        70         80         90        100        110        120 
GVSNPYVRNP VTIAAASTTL DEISNGRALL GVGPGDKATM ETLNLKWNKP LKTVKEAIQS 

       130        140        150        160        170        180 
IRLLTNGGKI EHGACLNGTS KIQDSIPIYM AAQGPKMLEA SGEVADGTLI NASNPKDFEI 

       190        200        210        220        230        240 
AIPLINKGLS KSSISQSKFN YAAYTSCSID NNIQQAYSQS KIVVAFIIGG APDIVLNRHN 

       250        260        270        280        290        300 
IPIEAAHKIR SCLGKYDFKG ASNLITEDMI HAFCVCGTPE DITNKIELLQ NIGVNEFVVG 

       310        320 
SPIGKDRIKS LKLLKDIINS FN

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References

[1]"The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis."
Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R., Gottschalk G., Thauer R.K.
J. Bacteriol. 188:642-658(2006) [PubMed: 16385054] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000102 Genomic DNA. Translation: ABC57510.1.
RefSeqYP_448153.1. NC_007681.1.

3D structure databases

ProteinModelPortalQ2NF93.
SMRQ2NF93. Positions 1-321.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2NF93.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3855523.
GenomeReviewsGene locus Msp_1128 in contig CP000102_GR.
KEGGmst:Msp_1128.
NMPDRfig|339860.6.peg.1081.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04928.
HOGENOMHBG497169.
OMAGIEFVPG.
ProtClustDBPRK02271.

Family and domain databases

HAMAPMF_01091. F420_mer.
[Tree]
InterProIPR011251. Luciferase-like_dom.
IPR019946. MeH4methanopterin_reductase.
[Graphical view]
Gene3DG3DSA:3.20.20.30. Luciferase_like. 1 hit.
KOK00320.
PfamPF00296. Bac_luciferase. 1 hit.
[Graphical view]
SUPFAMSSF51679. Luciferase_like. 1 hit.
TIGRFAMsTIGR03555. F420_mer. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2NF93_METST
AccessionPrimary (citable) accession number: Q2NF93
Entry history
Integrated into UniProtKB/TrEMBL: February 7, 2006
Last sequence update: February 7, 2006
Last modified: November 16, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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