Q2NES4 (Q2NES4_METST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
FrhA EMBL ABC57679.1
EC=1.12.98.1 EMBL ABC57679.1

Gene names

Name:	frhA EMBL ABC57679.1
Ordered Locus Names:	Msp_1302

Organism

Methanosphaera stadtmanae (strain DSM 3091) [Complete proteome] [HAMAP]

Taxonomic identifier

339860 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanosphaera

Protein attributes

Sequence length	406 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. RuleBase RU003896

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003896 Nickel RuleBase RU003896
Molecular function	Oxidoreductase RuleBase RU003896 EMBL ABC57679.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	coenzyme F420 hydrogenase activity Inferred from electronic annotation. Source: EC ferredoxin hydrogenase activity Inferred from electronic annotation. Source: InterPro flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro iron-sulfur cluster binding Inferred from electronic annotation. Source: InterPro nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q2NES4 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 1A231969814038D9	FASTA	406	44,981
	10 20 30 40 50 60 MSETIVISPT SRQEGHAELS MEVDENGIVT TGRYFSITPV RGIEKMVIGK RPETAPVLVQ 70 80 90 100 110 120 RICGVCPVTH TLASVEAIDD SLKIEVPQAG RILREMCLNA HMINSHAIHH FLVAPDFVPD 130 140 150 160 170 180 NQYKEVVKNI STIRKNAQYV EDTVGGEGIH PSDIRIGGMA HNITKNTKNK IKTRISGMMK 190 200 210 220 230 240 LLEEHVETMA GLIEDKDFPD KLGAHNQPVF ASDNTYGSKN NLSINEIEEI LPSSWYDLPD 250 260 270 280 290 300 IGERACSQIP LYKGNVVETG PRARASKFRK FKEVGVKAQH LARAQEMINS AEKILELVDK 310 320 330 340 350 360 LDTSAQVMAD YTLEGTNRLG VGVIEGPRGT NIHSAKISPE GYISYYNAIV PTTWNIPTMG 370 380 390 400 LATEGFHHEY APHVIRAYDP CLSCATHMIV KDDETKEVLK DDMVQL

References

[1]

"The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis." Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R., Gottschalk G., Thauer R.K. J. Bacteriol. 188:642-658(2006) [PubMed: 16385054] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000102 Genomic DNA. Translation: ABC57679.1.
RefSeq	YP_448322.1. NC_007681.1.
3D structure databases
ProteinModelPortal	Q2NES4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2NES4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3856135.
GenomeReviews	Gene locus Msp_1302 in contig CP000102_GR.
KEGG	mst:Msp_1302.
NMPDR	fig|339860.6.peg.1249.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04841.
HOGENOM	HBG287963.
OMA	DIXASCA.
PhylomeDB	Q2NES4.
ProtClustDB	CLSK2392607.
Family and domain databases
InterPro	IPR017682. Coenz_F420_hydrogenase_asu. IPR001501. Ni-dep_hyd_lsu. IPR018194. Ni-dep_hyd_lsu_Ni_BS. [Graphical view]
KO	K00440.
Pfam	PF00374. NiFeSe_Hases. 2 hits. [Graphical view]
TIGRFAMs	TIGR03295. FrhA. 1 hit.
PROSITE	PS00507. NI_HGENASE_L_1. 1 hit. PS00508. NI_HGENASE_L_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2NES4_METST

Accession

Primary (citable) accession number: Q2NES4

Entry history

Integrated into UniProtKB/TrEMBL:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	November 16, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)