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Protein

Adenine deaminase

Gene

ade

Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciMSTA339860:GJEZ-1309-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Msp_1308
OrganismiMethanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Taxonomic identifieri339860 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanosphaera
Proteomesi
  • UP000001931 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 542542Adenine deaminasePRO_0000292405Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi339860.Msp_1308.

Structurei

3D structure databases

ProteinModelPortaliQ2NER8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00693. Archaea.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NER8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIKGNILNV FTDEIYPGEI KIEHGIIESI KEVNADFNDI IVPGFIDAHI
60 70 80 90 100
HIESSMLTPS RFAEIALRHG TTSVIADPHE IANVMGMDGI DYMIDDAKKT
110 120 130 140 150
PLKYYFTAPS CVPATKFEKS GATISPNIID NLLSRPEFVA LGEVMDYNAV
160 170 180 190 200
ISNEKSILEK IKIAKKYHKP IDGHAPLLSG KNLQKYVKHG VITDHESTTK
210 220 230 240 250
KEVAEKKRMG MKIMIREGSE SKMLEKLIYS NCDFIVSDDL KPEDLINGHL
260 270 280 290 300
DKCLRKAVDY GMDPYEAIKL VTINPAEHYN LNAGSISPGK SADLVFIDNL
310 320 330 340 350
RDFTVKRVVI NGNTIFKKQK LLFRANPRPI DTTLHVSLTK PEDFDLKAQN
360 370 380 390 400
PAHKSATVNL INVSDNTIIT KQSSAKLSIQ KKTIIPSVFE DILKISVVDR
410 420 430 440 450
YGGNTISNGF VKGFGIKNGA IASSVSHDSH NIIVVGTNSE YMSRATNHLI
460 470 480 490 500
ENKGGLAAIS NQAKLDVTLP IAGLMSDKPA KVVANNSAKL NELVSNMGCE
510 520 530 540
LSSPFTSLSF MALPVVPEVK MTTNGLFNVN THQFIDIIKE EK
Length:542
Mass (Da):59,673
Last modified:February 7, 2006 - v1
Checksum:i0D7DD1B4B636449B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000102 Genomic DNA. Translation: ABC57685.1.
RefSeqiWP_011406884.1. NC_007681.1.

Genome annotation databases

EnsemblBacteriaiABC57685; ABC57685; Msp_1308.
GeneIDi3855936.
KEGGimst:Msp_1308.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000102 Genomic DNA. Translation: ABC57685.1.
RefSeqiWP_011406884.1. NC_007681.1.

3D structure databases

ProteinModelPortaliQ2NER8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi339860.Msp_1308.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC57685; ABC57685; Msp_1308.
GeneIDi3855936.
KEGGimst:Msp_1308.

Phylogenomic databases

eggNOGiarCOG00693. Archaea.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.

Enzyme and pathway databases

BioCyciMSTA339860:GJEZ-1309-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC_METST
AccessioniPrimary (citable) accession number: Q2NER8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: February 7, 2006
Last modified: November 11, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.