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Protein

DNA-directed RNA polymerase subunit H

Gene

rpoH

Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciMSTA339860:GJEZ-1377-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit HUniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoHUniRule annotation
Ordered Locus Names:Msp_1376
OrganismiMethanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Taxonomic identifieri339860 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanosphaera
Proteomesi
  • UP000001931 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7777DNA-directed RNA polymerase subunit HPRO_1000074386Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi339860.Msp_1376.

Structurei

3D structure databases

ProteinModelPortaliQ2NEK1.
SMRiQ2NEK1. Positions 1-77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04258. Archaea.
COG2012. LUCA.
HOGENOMiHOG000109413.
KOiK03053.
OMAiEHELVPK.

Family and domain databases

Gene3Di3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5.
InterProiIPR000783. RNA_pol_subH/Rpb5_C.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55287. SSF55287. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NEK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKADILQHKL VPEHTILSEE EAQKVLDDLN VRLDQIPKIL PTDPVVKAID
60 70
AKVGDILKIT RKSETAGIFV AYRVVRD
Length:77
Mass (Da):8,659
Last modified:February 7, 2006 - v1
Checksum:i6FD1B582E6403CCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000102 Genomic DNA. Translation: ABC57752.1.

Genome annotation databases

EnsemblBacteriaiABC57752; ABC57752; Msp_1376.
KEGGimst:Msp_1376.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000102 Genomic DNA. Translation: ABC57752.1.

3D structure databases

ProteinModelPortaliQ2NEK1.
SMRiQ2NEK1. Positions 1-77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi339860.Msp_1376.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABC57752; ABC57752; Msp_1376.
KEGGimst:Msp_1376.

Phylogenomic databases

eggNOGiarCOG04258. Archaea.
COG2012. LUCA.
HOGENOMiHOG000109413.
KOiK03053.
OMAiEHELVPK.

Enzyme and pathway databases

BioCyciMSTA339860:GJEZ-1377-MONOMER.

Family and domain databases

Gene3Di3.90.940.20. 1 hit.
HAMAPiMF_00025. RNApol_RpoH_RPB5.
InterProiIPR000783. RNA_pol_subH/Rpb5_C.
IPR020609. RpoH/RPB5.
[Graphical view]
PfamiPF01191. RNA_pol_Rpb5_C. 1 hit.
[Graphical view]
ProDomiPD005155. RNA_pol_subH/Rpb5_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF55287. SSF55287. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis."
    Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R., Gottschalk G., Thauer R.K.
    J. Bacteriol. 188:642-658(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3.

Entry informationi

Entry nameiRPOH_METST
AccessioniPrimary (citable) accession number: Q2NEK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 7, 2006
Last modified: November 11, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.