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Q2NE08 (Q2NE08_METST) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase HAMAP MF_00197
Short name=DAP epimerase HAMAP MF_00197
EC=5.1.1.7 HAMAP MF_00197
Gene names
Name:dapF HAMAP MF_00197 EMBL ABC57945.1
Ordered Locus Names:Msp_1579
OrganismMethanosphaera stadtmanae (strain DSM 3091) [Complete proteome] [HAMAP]
Taxonomic identifier339860 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanosphaera

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family. HAMAP MF_00197

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis HAMAP MF_00197
   Cellular componentCytoplasm HAMAP MF_00197
   Molecular functionIsomerase HAMAP MF_00197 EMBL ABC57945.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site781 By similarity HAMAP MF_00197
Active site2311 By similarity HAMAP MF_00197

Sequences

Sequence LengthMass (Da)Tools
Q2NE08 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: F4F4A0AC3810EDC8

FASTA29232,345
        10         20         30         40         50         60 
MIKEIEFTKM HALGNDYIVI NETETEVIPE EAKNKLSNDI CTRRFSVGSD GVIFACKSDK 

        70         80         90        100        110        120 
SDVRFRIFNS DGSEAEMCGN GIRCLAKYVY DNDIVKKQTM QIETMEDIKE ARLTVEDDVV 

       130        140        150        160        170        180 
KSIAIDMGKG FFKPEEIPAI APSGNTDEFI DEEIDVDGEK IIMSSVSVGN PHAVSFTDIN 

       190        200        210        220        230        240 
IDDIDLDYYG PRIENHKAFP EKVNVHFVNI VSPGEINILT WERGAGFTFA CGTGTTSCVL 

       250        260        270        280        290 
LGYKMGLLNE KVHAHLSGGD LDITVSDHNE YLTATMEGKA VTVYKAQMTV DI

« Hide

References

[1]"The genome sequence of Methanosphaera stadtmanae reveals why this human intestinal archaeon is restricted to methanol and H2 for methane formation and ATP synthesis."
Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R., Gottschalk G., Thauer R.K.
J. Bacteriol. 188:642-658(2006) [PubMed: 16385054] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000102 Genomic DNA. Translation: ABC57945.1.
RefSeqYP_448588.1. NC_007681.1.

3D structure databases

ProteinModelPortalQ2NE08.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ2NE08.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3855805.
GenomeReviewsGene locus Msp_1579 in contig CP000102_GR.
KEGGmst:Msp_1579.
NMPDRfig|339860.6.peg.1512.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG07445.
HOGENOMHBG399442.
OMAFMTGPAT.
PhylomeDBQ2NE08.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2NE08_METST
AccessionPrimary (citable) accession number: Q2NE08
Entry history
Integrated into UniProtKB/TrEMBL: February 7, 2006
Last sequence update: February 7, 2006
Last modified: November 16, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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