Q2ND35 (Q2ND35_ERYLH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP MF_00123
EC=6.1.1.19 HAMAP MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP MF_00123

Gene names

Name:	argS HAMAP MF_00123
Ordered Locus Names:	ELI_01570

Organism

Erythrobacter litoralis (strain HTCC2594) [Complete proteome] [HAMAP]

Taxonomic identifier

314225 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter

Protein attributes

Sequence length	581 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm By similarity HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00123 RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00123 RuleBase RU003489
Cellular component	Cytoplasm HAMAP MF_00123
Ligand	ATP-binding HAMAP MF_00123 RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP MF_00123 RuleBase RU003489 EMBL ABC62406.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	135 – 145	11	"HIGH" region By similarity HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q2ND35 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 6BC2DF81B1F6460B	FASTA	581	63,504
	10 20 30 40 50 60 MSELNTIHAA FAAKVDAVLS ALEAEGTLPA GVERRNVTVE PPRDPSHGDL ATNAAMVLAK 70 80 90 100 110 120 QAATNPRALA EKIVEHLERD PDITETAIAG PGFINLRLAD RAWLGELEAI AALGEGYGRS 130 140 150 160 170 180 QMGEGKRVNV EYVSANPTGP MHMGHCRGAV VGDALAALLE YAGHEVTREY YVNDAGGQVD 190 200 210 220 230 240 TLARSAHLRY REALGEDIGA IPGGLYPGDY LKPVGEYLAQ ELGDRFKDAP EDEWLPIFRA 250 260 270 280 290 300 EAVEKMMDVI RADLALLGIH HDLFSSEAAL QAAGKPEQAE AWLREHGLVY DGVLEQPKGK 310 320 330 340 350 360 VIEDWEPVEL PLFRSTKFGD DQDRPIRKSD GKWTYFGADL AYHMQKAEEA DALIDIWGAD 370 380 390 400 410 420 HAGTVKRIKA AVAALSEGQG KPIPFDVKLV QMVQLMRAGE PVKMSKRSGN FITIADMVEE 430 440 450 460 470 480 VGKDVVRFTM LTRKPEAQMD FDFAKVVEAS KDNPVFYVQY AHARIHSTLR KARAEGIEPS 490 500 510 520 530 540 TEAIAQLGEE ELGLIKQAAQ FPRIVEAAAA AREPHRIAFF LYDLASAFHS FYNLGNDNPS 550 560 570 580 KRVILAQDPA LSAARLFLID TIGQVIRNGL TLLGVEAVEE M

References

[1]	"Complete genome sequence of Erythrobacter litoralis HTCC2594." Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C. J. Bacteriol. 191:2419-2420(2009) [PubMed: 19168610] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000157 Genomic DNA. Translation: ABC62406.1.
RefSeq	YP_457203.1. NC_007722.1.
3D structure databases
ProteinModelPortal	Q2ND35.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2ND35.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3871874.
GenomeReviews	Gene locus ELI_01570 in contig CP000157_GR.
KEGG	eli:ELI_01570.
NMPDR	fig|314225.3.peg.2775.
PATRIC	21857738. VBIEryLit102657_0315.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0018.
HOGENOM	HBG695395.
OMA	ETIRGCL.
PhylomeDB	Q2ND35.
ProtClustDB	PRK01611.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01887.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. ArgS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q2ND35_ERYLH

Accession

Primary (citable) accession number: Q2ND35

Entry history

Integrated into UniProtKB/TrEMBL:	February 7, 2006
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)