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Q2NCW5 (Q2NCW5_ERYLH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:ELI_01920
OrganismErythrobacter litoralis (strain HTCC2594) [Complete proteome] [HAMAP]
Taxonomic identifier314225 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter

Protein attributes

Sequence length160 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818 SAAS SAAS016856

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818 SAAS SAAS016856

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818 SAAS SAAS016856

Subcellular location

Cytoplasm By similarity HAMAP MF_00818 SAAS SAAS016856.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
Q2NCW5 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: F8C27AC6338595C5

FASTA16017,469
        10         20         30         40         50         60 
MRGMSDTPTP AEGAPQFLGK QTALPASPED AVLDYVPNPR PGALYLVRFA APEFTSLCPV 

        70         80         90        100        110        120 
TGAPDFAHLV IDYAPGDTVV ESKSLKLFLG SFRNHNGFHE DVTVGIGQRL NEEMRPRWLR 

       130        140        150        160 
IGGYWYPRGG IPIDVFWQSG PSPEGLWVPD QGVAGYRGRG

« Hide

References

[1]"Complete genome sequence of Erythrobacter litoralis HTCC2594."
Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C.
J. Bacteriol. 191:2419-2420(2009) [PubMed: 19168610] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000157 Genomic DNA. Translation: ABC62476.1.
RefSeqYP_457273.1. NC_007722.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2NCW5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3869663.
GenomeReviewsGene locus ELI_01920 in contig CP000157_GR.
KEGGeli:ELI_01920.
NMPDRfig|314225.3.peg.2704.
PATRIC21857878. VBIEryLit102657_0385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0780.
HOGENOMHBG294103.
OMAHEDCTVA.
ProtClustDBPRK13258.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ2NCW5_ERYLH
AccessionPrimary (citable) accession number: Q2NCW5
Entry history
Integrated into UniProtKB/TrEMBL: February 7, 2006
Last sequence update: February 7, 2006
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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