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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Erythrobacter litoralis (strain HTCC2594)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:groEL1UniRule annotation
Ordered Locus Names:ELI_04155
OrganismiErythrobacter litoralis (strain HTCC2594)
Taxonomic identifieri314225 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesErythrobacteraceaeErythrobacter
Proteomesi
  • UP000008808 Componenti: Chromosome

Subcellular locationi

Q2NBL8:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003319971 – 53960 kDa chaperonin 1Add BLAST539

Proteomic databases

PRIDEiQ2NBL8.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi314225.ELI_04155.

Structurei

3D structure databases

ProteinModelPortaliQ2NBL8.
SMRiQ2NBL8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiVTNQDKM.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q2NBL8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKEVKFAS DARDRMLRGV DTLANAVKVT LGPKGRNVVI EKSFGAPRIT
60 70 80 90 100
KDGVTVAKEI ELKDKFENMG AQMLREVASK QNDKAGDGTT TATVLAQAIV
110 120 130 140 150
REGAKAVAAG MNPIDLKRGI DLAVGTVVKD LESHAKKVSA NSEIAQVATI
160 170 180 190 200
SANGDETVGR FLAEAMDKVG NEGVITVEEA KSLETELETV EGMQFDRGYL
210 220 230 240 250
SPYFVTNTEK LKVELEDPYI LIHEKKLSNL QALIPLLEQV VQSGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKVAAVKAPG FGDRRKAMLE DVAILTAGNV
310 320 330 340 350
VSEELGTKLE NVTIGMLGRA KKVIIDKDNT TIVDGAGNKA DIDARVSQIR
360 370 380 390 400
AQIETTTSDY DREKLQERVA KLAGGVAVIR VGGATEVEVK ERKDRVDDAL
410 420 430 440 450
HATRAAVEEG ILPGGGIALL RALKSLDGLK AANDDQQSGI DIVRRALRAP
460 470 480 490 500
ARQIAENAGE DGAYIVGKLL EGDDYNHGFN AATGEYEDLV KSGVIDPAKV
510 520 530
VRTALQDAAS VASLLITTEA LVAELPKEDT PAPMPAMDF
Length:539
Mass (Da):57,344
Last modified:February 7, 2006 - v1
Checksum:iF67C7DD4F43837BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000157 Genomic DNA. Translation: ABC62923.1.
RefSeqiWP_011413797.1. NC_007722.1.

Genome annotation databases

EnsemblBacteriaiABC62923; ABC62923; ELI_04155.
KEGGieli:ELI_04155.

Similar proteinsi

Entry informationi

Entry nameiCH601_ERYLH
AccessioniPrimary (citable) accession number: Q2NBL8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: February 7, 2006
Last modified: October 25, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families