Q2N9N2 (TRPF_ERYLH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	ELI_07585

Organism

Erythrobacter litoralis (strain HTCC2594) [Complete proteome] [HAMAP]

Taxonomic identifier

314225 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000018594

Sequences

	Sequence		Length	Mass (Da)
	Q2N9N2 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: 76122A1A646B25AB	FASTA	209	22,364
	10 20 30 40 50 60 MTMIKICGLS TPETIEAAVQ AGATHVGLVH FAKSPRHVEL EKAAELRALV PESVKAVLLL 70 80 90 100 110 120 VNEQPEETAR AIQIVKPDVV QFHGSETPQW TKAVRDQLGI EVWKALGVRE AATLEKSRRY 130 140 150 160 170 180 EGAVDRLLFD SPAKKLPGGN GVTFQWDVLA GFEHHTAWGL AGGLTPDNVG DAIRQTGAEL 190 200 VDASSGVESA PGVKDIAKIE AFCEAARNA

References

[1]	"Complete genome sequence of Erythrobacter litoralis HTCC2594." Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C. J. Bacteriol. 191:2419-2420(2009) [PubMed: 19168610] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTCC2594.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000157 Genomic DNA. Translation: ABC63609.1.
RefSeq	YP_458406.1. NC_007722.1.
3D structure databases
ProteinModelPortal	Q2N9N2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2N9N2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3871535.
GenomeReviews	Gene locus ELI_07585 in contig CP000157_GR.
KEGG	eli:ELI_07585.
NMPDR	fig|314225.3.peg.1525.
PATRIC	21860164. VBIEryLit102657_1507.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HBG554803.
OMA	TGEAFDW.
PhylomeDB	Q2N9N2.
ProtClustDB	CLSK753564.
Enzyme and pathway databases
BioCyc	ELIT314225:ELI_07585-MONOMER.
Family and domain databases
HAMAP	MF_00135. PRAI. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01817.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_ERYLH

Accession

Primary (citable) accession number: Q2N9N2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program