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Q2N7I6 (Q2N7I6_ERYLH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:ELI_11315
OrganismErythrobacter litoralis (strain HTCC2594) [Complete proteome] [HAMAP]
Taxonomic identifier314225 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1961Iron By similarity HAMAP MF_00323
Metal binding2811Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q2N7I6 [UniParc].

Last modified February 7, 2006. Version 1.
Checksum: 66222D5FB6F1122B

FASTA33036,247
        10         20         30         40         50         60 
MNSGKVGVLL VNLGTPAAPD TGSVRTYLAE FLSDKRVVEI PSLIWQPILR GIILNTRPKK 

        70         80         90        100        110        120 
SAAAYKKVWG EAGSPLAAIT ERQAKALQVR LGDAVQVDWA MRYGKPSIAE RMQAMMDAGC 

       130        140        150        160        170        180 
ERILFAPLYP QYSGATTATA VDKVADVLRA MRWQASLRTL PPYHDHPSYI DALAADTMRQ 

       190        200        210        220        230        240 
LDALDFVPEV LLLSFHGMPL RTLELGDPYH CHCHKTARLL GERLHASDKW RDLRLVTSFQ 

       250        260        270        280        290        300 
SRFGRAKWLE PATDETIEAE AHAGTKRMAV AMPGFSADCL ETLEEIAMEG RGTFLAAGGE 

       310        320        330 
HYAALACLND GATGMDMIEA LVRQELAGWV

« Hide

References

[1]"Complete genome sequence of Erythrobacter litoralis HTCC2594."
Oh H.M., Giovannoni S.J., Ferriera S., Johnson J., Cho J.C.
J. Bacteriol. 191:2419-2420(2009) [PubMed: 19168610] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000157 Genomic DNA. Translation: ABC64355.1.
RefSeqYP_459152.1. NC_007722.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ2N7I6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3871285.
GenomeReviewsGene locus ELI_11315 in contig CP000157_GR.
KEGGeli:ELI_11315.
NMPDRfig|314225.3.peg.759.
PATRIC21861661. VBIEryLit102657_2247.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBQ2N7I6.
ProtClustDBCLSK844073.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ2N7I6_ERYLH
AccessionPrimary (citable) accession number: Q2N7I6
Entry history
Integrated into UniProtKB/TrEMBL: February 7, 2006
Last sequence update: February 7, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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