Reviewed, UniProtKB/Swiss-Prot Q2N784 (GLND_ERYLH)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	ELI_11825

Organism

Erythrobacter litoralis (strain HTCC2594) [Complete proteome] [HAMAP]

Taxonomic identifier

314225 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Erythrobacteraceae › Erythrobacter

Protein attributes

Sequence length	919 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 919	919	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_1000022343

Sequences

	Sequence		Length	Mass (Da)
	Q2N784-1 [UniParc]. Last modified February 7, 2006. Version 1. Checksum: B532D60CE3188D12	FASTA	919	104,003
	10 20 30 40 50 60 MTDPKVPRQR RIIDRRKLAA AVEALAEQQG EKARPAVLKV LREALEKGRD ELSQRLLDRP 70 80 90 100 110 120 SAGHQITAGH AFLVDQLVRV IFDHVTTHLY PVANRSSSER IAVLAVGGYG RAEMAPQSDV 130 140 150 160 170 180 DIAFLHPSRR TPWCEQVTEA MLYFLWDLGF KVGQSSRTPE DMVRMAREDL TIRTALLEAR 190 200 210 220 230 240 FVWGDRELYD EARKRFWSEV VNGTERQFVA EKLAERDARH ERMGGTRYVV EPNVKEGKGG 250 260 270 280 290 300 LRDLQTLYWI GKYIHRARGA AELVDAGLLT ETEYHGFRRA EGFLLAVRCH LHEITGRPED 310 320 330 340 350 360 RLTFDFQKQI AERMRFAERR EKSAVERFMQ YYFLQVKRVG SLTGVFLAQM DQQFARKRAR 370 380 390 400 410 420 TGLLAGFNAK SRMLKGYTVF GGKIAAPGDN WFRDDPVRLI EIFQLAEANG LEIDPRSMRQ 430 440 450 460 470 480 ADRDSVLIKD QVRNDPRANA IFLDLLCGRN DPETALRWMN EAGVFGKFVP DFGRVNAQMQ 490 500 510 520 530 540 FNMYHHYTVD EHTIRAIGFL SKIEKGELAK EHPRSTREIH KVKSRRVAFV AALLHDIAKG 550 560 570 580 590 600 RGGDHSILGA EVAEELCPRF GLDEDETDLV AWLVLQHLLM SSTAQKRDLT DPKTIEDFVA 610 620 630 640 650 660 EVQSLERLRH LAILTSVDIR AVGPGTWNSW KGQLLGELYD AAHERLRLGH MKHHRSERVA 670 680 690 700 710 720 AKKEAVREAL GGKAALLEKH GRLLPDSYWI AEPENVISRN IVQYDVAREI SEDLSIHCEF 730 740 750 760 770 780 DEERGATLVT VIAADHPGLF YRIAGGIHLA GGNIIDARIH TTRNGWAIDN YLVQDPVGQP 790 800 810 820 830 840 FAEERQLARI EQAIADAIAN RGELVPKLAK RPLKQTRAGA FDVRPRVLFD NDASGRFTVI 850 860 870 880 890 900 EVNARDRAAL LNRLGRALFE NQVIVQSAHI TAYGERAADT FYVTDLTGAK ITDESRMDTI 910 RQALLDAASD ARQAELEPA

References

[1]	Giovannoni S.J., Cho J.-C., Ferriera S., Johnson J., Kravits S., Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000157 Genomic DNA. Translation: ABC64457.1.
RefSeq	YP_459254.1.
3D structure databases
SMR	Q2N784. Positions 65-341, 382-615.
ModBase	Search...
Protein-protein interaction databases
STRING	Q2N784.
Genome annotation databases
GeneID	3871505.
GenomeReviews	Gene locus ELI_11825 in contig CP000157_GR.
KEGG	eli:ELI_11825.
NMPDR	fig|314225.3.peg.660.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HBG687872.
OMA	MQHDLFH.
PhylomeDB	Q2N784.
Enzyme and pathway databases
BioCyc	ELIT314225:ELI_11825-MONOMER.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. [Tree]
InterPro	IPR005105. DUF294_Ntrans. IPR010043. GlnD_Uridyltrans. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF03445. DUF294. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_ERYLH

Accession

Primary (citable) accession number: Q2N784

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 7, 2006
Last modified:	February 9, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)